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- Cytogenetically, Ph chromosome was seen in 25.5%( 13/51) of patients with BAL. 核型分析揭示BAL中Ph染色体较多见，占25.;5%25(13/51)；
- Objective:To investigate the value of detection of Ph chromosome and bcr/abl fusion gene in the diagnosis of CML. 目的 :观察Ph染色体 ,bcr/abl融合基因与慢性粒细胞白血病 (CML)的诊断指标。
- Chronic myelogeous leukemia (CML) is a clonal disorder of a pluripotent hematopietic stem cell associated in over 95%of cases with the Ph chromosome. 慢性粒细胞白血病(CML)是骨髓多能造血干细胞恶性增殖性疾病。
- Four in 485 CML cases (0. 9%) were not detected with typical Ph chromosome by G-banding, but with Ph-masked variant translocation by FISH. 485例CML患者中4例经常规G显带技术未见典型Ph染色体;FISH检出具有隐匿型Ph染色体(0.;9%25)。
- Method:Bcr/abl fusion gene and Ph chromosome were assayed by RT-nest-PCR and routine cytogenetic analysis, respectively. 方法:分别采用RT-nest-PCR法和常规细胞遗传学方法检测bcr/abl融合基因和Ph染色体。
- Methods:To detect mRNA levels of bcr-abl fusion gene of 36 patients with CML by RQ -PCR and nested RT-PCR ,Ph chromosome using cytogenetic study. 方法:采用实时定量逆转录聚合酶链反应(Real-time quantitative RT-PCR,RQ-PCR)及巢式RT-PCR方法检测36例CML患者bcr-abl mRNA; 并用细胞遗传学方法检测Ph染色体。
- The chimeric oncogene BCR/ABL and Ph chromosome,two hall marks of CML,were detected in CML derived MSCs,normal adult MSCs,CML derived hematopoietic cells and K562 cells. RT-PCR检测CML特异性表达的BCR/ABL基因; 对正常人、CML患者的骨髓间质干细胞进行染色体分析。
- Objective:To investigate the value of the detection of Ph chromosome and bcr/abl fusion gene in the diagnosis? treatment and prognosis in chronic myelogenous leukemia (CML). 目的 :观察 Ph染色体、bcr/ abl融合基因与慢性粒细胞白血病 (CML)诊断、疗效、预后的关系。
- Methods:Bone marrow mononuclear cells(MNCs) from 10 newly diagnosed Ph chromosome positive CML patients in chronic phase were separated and cultured in vitro for 10 days. 方法 :分离 10例初诊的慢性期Ph+ CML患者骨髓单个核细胞 (MNC) ,体外培养 10天 ,利用染色体分析法检测培养前后Ph+ 中期细胞比例 ;
- Philadelphia chromosome(Ph chromosome) 费城染色体, Ph染色体
- Ph chromosome, a specific marker of CML, was assayed by conventional chromosomal analysis and fluorescence in situ hybridization, bcr/abl fusion gene was detected by reverse transcription-polymerase chain reaction. RT-PCR检测bcr/abl融合基因; 常规染色体核型分析及FISH检测细胞遗传学变化。
- That word is spelt with a PH, not an F. 那个字里的f音拼作PH而不是F。
- Two Ph chromosome positive chronic myelogenous leukemia patients with rare bcr/abl fusion gene 两例Ph染色体阳性慢性粒细胞白血病患者具有少见型bcr/abl融合基因
- Analysis of factors associated with prognosis in patients with Ph chromosome positive adult acute lymphoblastic leukemia Ph染色体阳性成人急性淋巴细胞白血病患者预后相关因素分析
- The position that a given gene occupies on a chromosome. 基因座在一条染色体上某种给定基因所占的位置
- A chromosome composed primarily of heterochromatin. 异染色体主要由异染色质组成的染色体
- These are likely for use in the al-Samud II (ph). 这些发动机用于生产al-SamudII导弹。
- A buffer system resists a change in pH. 缓冲系统对pH的变化是有耐受能力的。
- Chromosome 5 is distinguished by a proximal knob. 第5染色体的特点是有一个近侧的节结。
- Several copies of specific chromosome are present. 特殊染色体存在着几个拷贝。
