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- Keywords perchloroethylene;human epidermis keratinocytes;cytotoxicity; 四氯乙烯;角质形成细胞;细胞毒性作用;
- Methods: Human epidermal keratinocytes(cell line HaCaT) were cultured in vitro. After treated with certain concentration of arsenic,the expressions of CDK2,CDK4 and cyclin-E were measured by immunoblot test. 方法:以体外培养的角质形成细胞株为对象,一定浓度砷剂处理细胞后,用免疫印迹方法研究HaCaT细胞周期蛋白依赖激酶2(CDK2)、周期蛋白依赖激酶4(CDK4)和细胞周期蛋白E(Cyclin-E)的表达情况及砷剂对其表达的影响。
- Human epidermis keratinocytes 角质形成细胞
- Cytotoxicity of Perchloroethylene on Normal Human Epidermal Keratinocytes 四氯乙烯对人原代角质形成细胞的细胞毒性作用
- IntroductionNormal human epidermis is mainly composed of keratinocytes ( KC) , Langerhans cells ( LC ) , melanocytes, indeterminate dendritic cells, Merkel cells and lymphocytes. 表皮由角质形成细胞(keratinocytes,KC)、朗格汉斯细胞(Langerhans cells,LC)、黑色素细胞、未定型细胞、Merkel细胞、淋巴细胞等组成,其中KC占表皮细胞总数的95%25左右,LC约占表皮细胞总数的2%25-5%25。
- Objective To explore the phenotype changing of human epidermis transplanted to subcutaneous area of athymic mouse. 目的研究人表皮移植至裸鼠皮下后表皮细胞的表型变化。
- Objective To observe the expression and role of HSP70 in human epidermis and cutaneous neoplasms. 目的为研究Hsp70在人类表皮和表皮肿瘤疾病中的表达和作用。
- Richard Bruck, et al., “The effect of ultrasound on the in vitro penetration of ibuprofen through human epidermis,” Pharmaceutical Research, 1989, pp.411-420. 童华、胡晋红、范国荣,“低频超声导入法透皮给药研究进展”,第二军医大学附属长海医院药学部。
- Objective To establish the method for extracting the cytokeratin filament aggregating protein (filaggrin) from human epidermis,to detect the anti filaggrin antibody (AFA) in rheumatoid arthritis (RA) and to determine the diagnostic value of AFA in RA. 目的 建立从人表皮提取聚角蛋白微丝蛋白 (filaggrin)抗原的方法 ,检测抗filaggrin抗体 (AFA)在类风湿关节炎 (RA)中的分布 ,探讨AFA对早期RA诊断的价值。
- Strong immunoreactivty of TARC was observed in the epidermal keratinocytes of 11 cases of the lesional skin of patients with BP. TARC在大疙性类天疙疮皮损中表达明显上调,12例大疙性类天疙疮有n例表皮均有不同程度的表达(1+一2+);
- Epidermal keratinocytes produced angle, such as cattle, sheep skin sheath and rhinoceros skin Kok, dermal bone formation angle, such as the Antlers. 表皮产生角质角,如牛、羊的角质鞘及犀的表皮角,真皮形成骨质角,如鹿角。
- Human epidermal keratinocyte 角质形成细胞
- The apoptosis of epidermal keratinocytes plays an important role in maintaining the balance of skin development and refreshment, and closely relates with the propagation of these cells. 表皮细胞凋亡在皮肤发育及更新平衡稳定中起着重要的作用,与表皮细胞增殖密切相关。
- It's only human nature to want a comfortable life. 想过舒适的生活不过是普通人的本性。
- Objective To study the expression of CD44V6 in human epidermal tumours and malignant melanoma. 目的研究CD44V6在鳞状细胞癌、基底细胞癌和恶性黑素瘤的表达。
- Objective Try to provide the human epidermic cells for the treatment of burn or trauma. 摘要目的为提供烧伤、创伤大面积皮肤缺损修复时所需的表皮细胞。
- MYC in human epidermal stem cells can stimulate differentiation rather than uncontrolled proliferation. 人类上皮干细胞中的MYC可以刺激分化而非无法控制的增殖。
- Conclusion:Mixed culture of human epidermic cell can be a good way for those patients in serious burn injury. 结论:该方法简单易行,为缺乏皮源的烧伤病人提供了一个可用的方法。
- It will increase the water content of the stratum corneum, so as to reduce the extent of the epidermal keratinocyte. 提高角质层的水分含量,使表皮角质化的程度减弱。
- Purification and identification of the human epidermis filaggrin 人表皮丝集蛋白的纯化和鉴定