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- Progenics has been testing a different type of entry inhibitor, a molecular decoy for CD4 whose job is to find, bind and lure HIV away from the real CD4 cells. 普罗基尼克斯制药公司一直在检测一种不同类型进入抑制剂C1)4的分子引诱物,这种分子引诱物的作用是发现井结合、引诱HIV与真正的CD4细胞分开。
- It belongs to a family of molecules known as entry inhibitors that, as the name suggests, prevent HIV's entry into healthy immune cells. 这种化合物属于人们所称的进入抑制剂的一类分子,顾名思义,它能防止hiv进入健康免疫细胞。
- Objective Plasmid of AAV vector with HIV 1 gag and gp 120 were constructed respectively. 目的 构建带有HIV 1gag或 gp12 0基因的重组腺病毒伴随病毒AAV HIV gag或AAV HIVgp12 0。
- The HIV 1 capsid protein(CA) plays an essential role in viral core assembly and maturation. 人类免疫缺陷病毒(HIV)的壳体蛋白(CA)在HIV病毒的组装和成熟过程中起着至关重要的作用。
- This Event error indicates that the Recipient Update Service could not be initialized because the %1 entry point could not be found in file %2. 此事件错误表示收件人更新服务无法初始化,因为在文件%252中找不到入口点“%251”。
- The discovery of HIV 1 corecptor and the role of the coreceptor CCR 5 in HIV 1 infection and disease progression are reviewed. 简述了HIV-1辅助受体的发现过程及辅助受体CCR-5在HIV-1感染及发病过程中的作用。
- The domain epidemic strains in the area were mainly from HIV 1 American European strain, B subtype of Thailand strain and their derivative strains. 这一结果提示,在进化上云南瑞丽HIV?1流行毒株间有非常密切的关系,在这一时期该地区的流行毒株以HIV?1美欧株、泰国株B亚群及其衍生株为主。
- The amino acid sequence in all of these 6 clones is the same,HYEFWAWNWEAN, which is hydrophobic as N terminal of C34.Conclusion This phage display peptide can mimic the epitope of HIV 1 gp41 CHR ,and bind with HIV 1 gp41 NHR. 上述 6个阳性克隆经DNA测序 ,氨基酸序列相同 :HYEFWAWNWEAN ,其明显的疏水性质类似于C34N末端 ,特异性鉴定显示这些克隆均能够与HIV 1gp4 1N多肽结合。 结论 该噬菌体克隆展示肽可模拟HIV 1gp4 1CHR多肽表位 ,并可与N多肽结合
- AIM: To construct the recombinant adenoviral vector carrying antisense RNA to chemokine receptors CCR5 and CXCR4 and to obtain recombinant adenovirus, which will be used to resist HIV 1 infection. 目的 :构建趋化因子受体CCR5 ;CXCR4双靶区反义RNA重组载体并获取重组腺病毒以用于抗HIV 1基因治疗的研究 .
- Methods 24 HIV 1 infected patients and 13 normal controls were tested and a three color flow cytometry was used to detect the activation marker HLA DR and the coreceptor CCR5, CXCR4 expressions in blood samples taken from the patients and the controls. 方法 用三色标记法流式细胞术检测 2 4例HIV 1感染者及 13例健康对照的抗凝血标本 ,分析活化标志物HLA DR及第二受体CCR5、CXCR4的表达等指标。
- Keywords HIV 1 infection;Viral load;NASBA; 关键词HIV-1感染;病毒载量;等温核酸序列扩增技术(NASBA);
- Keywords HIV 1;capsid;virus like particle;vaccine; 壳体蛋白;病毒样颗粒;疫苗;
- This city has a population of more than 1,000,000. 这个城市人口超过一百万。
- Keywords HIV entry inhibitors;cell fusion;syncytium formation;high content screening; 关键词HIV进入抑制剂;细胞融合;合胞体形成;高内涵药物筛选;
- These socks retail at 1 dollar a pair. 这些袜子零卖一美圆一双。
- This mountain is 1,400 meters above sea level. 这座山海拔1,400米。
- These socks are going at 1 a pair. 这些短袜每双卖1英镑。
- Sifuvirtide, an HIV fusion inhibitor, is the leading drug candidate of FusoGen. 其中抗艾滋病新药西夫韦肽,为公司发展的最为快速的产品。
- The ratios of 1 to 5 and 20 to 100 are the same. 1与5之比和20与100之比相同。
- The thieves stole 1 million worth of jewellery. 窃贼偷走了价值100万英镑的珠宝。