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- Orthogonal project with multiple linear regression was employed to establish the relation between the amount of HPMC, Carbomer and the dissolution rate in vitro . 采用正交设计结合多元线性回归的方法,确定生物粘附材料羟丙甲纤维素、卡波姆的用量及配比与制剂体外释放度的关系。
- METHODS:Artificial gastric juice was used as the dissolution medium ,the tinidazole was determined by UV and the dissolution rate in vitro of four tinidazole solid preparations was estimated. 方法:选用人工胃液为溶出介质,以紫外分光光度法测定替硝唑的含量和各制剂的体外溶出度,用单指数模型法,威布尔分布模型法,以及希古契方程拟合。
- The dissolution rates in vitro of ursolic acid solid dispersion were obviously raised, and PVP-k30 was a better carrier in increasing the dissolution rate than Poloxamer 188. 以聚乙烯吡咯烷酮为载体制备的固体分散体溶出速度快于泊洛沙姆。
- accumulative dissolution rate in vitro 体外累积释放度
- Results: The dissolution rates in vitro of the active components of extraction of Radix Arnebiae seu Lithospermi solid dispersion were obviously raised and stable, and the... 结果:制备的固体分散物紫草浸膏的有效成分体外溶出速度有明显增加且稳定,无老化现象。
- Objective: To improve the dissolution rate of nifedipin tablets in vitro. 目的:提高硝苯地平片的体外溶出速率。
- Dissolution rate in vitro 体外溶出
- Objective:To compare dissolution rate of first-researching and imitating Ebastine tablets in vitro. 目的:比较原研和仿制药厂生产的依巴斯汀片的体外溶出度特性。
- Objective To study the behavior of Phentolamine Mesylate Tablets in vitro, and determinate the condition of its dissolution rate. 目的考察甲磺酸酚妥拉明片的体外释放行为,制订合理的溶出度测定条件。
- Cyclodextrin inclusion technique can remarkably improve the solubility of itraconazole in water and the dissolution rate of itraconazole in vitro. 体外溶出结果表明，固体分散物能显著提高药物在人工胃液中的溶出度。
- Keywords isosorbide dinitrate（ISDN）;solid dispersion;solution;dissolution rates in vitro; 硝酸异山梨酯;固体分散体;溶解度;溶出速率;
- Xu0 (mEq): 27.78 and 27.06. The correlations between in vivo input rate and in vitro dissolution rate of TT and RT were: rrr=0.9471 (p=0.217) and rRT=0.9617 (p=0.177). 体内累积吸收率和体外累积释放率的相关性分别为：r_(TT)=0.;9471(p=0
- Objective To prepare Mosaperide Citrate Dispersed Tablets(MCDT), study the character of its dissolubility and study the possible influencing factors of in vitro dissolution rate. 目的制备枸橼酸莫沙必利分散片,考察其体外溶出特性,并对影响其体外溶出度的影响因素进行考察。
- Methods The dissolution rate of ultra-fine ERMIAO PILL with different granule diameters in vitro was measured and compared with the index of berberine by UV spectro-photometry. 方法采用分光光度法,以盐酸小檗碱为指标成分,考察普通粉与超细粉二妙丸及不同粒径的超细粉二妙丸微丸的体外溶出度。
- The basal properties,application in food industry of neotame and methods to improve the solubility and dissolution rate in water of neotame are detailed in this paper. 全面介绍了纽甜的基本性质、在食品工业中的应用以及提高纽甜在水中的溶解度和溶解速率的方法。
- Objective:To prepare the microcapsules of dirithromycin and to study its release rate in vitro. 目的:制备地红霉素微囊并考察其体外释放度。
- The birth rate in this city is almost constant. 这城市的出生率几乎是不变的。
- AIM: To study the correlation between the release rate in vitro and the absorption in vivo of Shenshen sustained-release Capsule(SSRC phenylethanoid glycosides). 目的:考察肾参缓释胶囊(苯乙醇苷)的体外释放度与体内吸收的相关性。
- A simple,rapid and accurate method for the release rate in vitro of adriamycin in adriamycin gelatin microspheres was founded. 该方法简便、快速、准确,可作为阿霉素微球体外释放度的测定方法。
- Objective:To prepare nicardipine hydrochloride sustained-release pellets,and to research factors affecting the release rate in vitro. 目的:制备盐酸尼卡地平缓释微丸,并考察影响其溶出度的因素。
