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- Caspase 3 inhibitor 半胱氨酸天冬氨酸蛋白酶3抑制剂
- Objective To investigate the expression of Caspase 3 in the hippocampus of acutely pentylenetetrazole-kindled rats. 目的 研究 Caspase- 3在戊四氮 (pentylenetetrazole,PTZ)急性点燃大鼠海马组织中的表达情况。
- The serum alanine transferase (ALT), hepatic Fas mRNA, caspase 3 activity and hepatocyte apoptosis were analyzed. 测定各组的血清谷丙转氨酶 (ALT)、肝组织Fas mRNA表达、caspase 3活性和肝细胞凋亡。
- The presence of single-stranded DNA, Caspase 3, and TNF further confirmed the occurrence of DRG cell apoptosis. 单链DNA、半胱天冬酶3以及TNF的表达更进一步证实了DRG细胞调亡的存在。
- In some renal biopsies, immunohistochemical staining for actiated caspase 3 was performed. 在一些肾脏活检标本中,免疫组化染色可检测到半胱天冬酶3的表达。
- Staining for actiated caspase 3 in selected biopsies confirmed the presence of apoptosis. 在选取肾活检的病例中活化半胱天冬酶3染色证实了凋亡的存在。
- Phosphodiesterase 3 inhibitor attenuates cough response in a sensitized guinea pig model. 中国病理生理杂志,第二,2007年,in press。
- The expression of Caspase 3 mRNA in the inflammation group was intensified compared with that of the pre treatment group. 炎症组的Caspase 3mRNA表达强于预处理组。
- Z DEVD AMC substrate cleavage and TBARS methods were used to measure the activity of caspase 3 and the content of lipid peroxide in right ventricular myocardium,respectively. 分别用Z DEVD AMC底物降解法和TBARS方法测定右心室caspase 3活性和MDA含量。 结果 CHD病人右心室心肌细胞凋亡数、caspase 3活性和MDA含量均明显高于ASD病人 (分别P =0 0 2 6,0 0 13和 0 0 0 2 ) ;
- ZDEVD AMC substrate cleavage and TBARS methods were used to examine the activity of caspase 3 and the content of lipid peroxide in right ventricular myocardium,respectively. 用Z DEVD AMC底物降解法和TBARS方法分别测定右心室心肌caspase 3酶活性和脂质过氧化物含量(MDA)。
- We determined the expression of caspase 3 and bcl 2 ,cell cycle and apoptotic rate in thymus,bursa of Fabricius and spleen from 30 day old AA chickens with flow cytometry. 用流式细胞法测定了 30日龄AA肉鸡的胸腺、法氏囊和脾脏细胞中半胱天冬酶 3(caspase 3)、Bcl 2蛋白的表达及细胞周期和细胞凋亡率。
- Caspase 3, glutathione S-transferase pi, SAFB, and Topisomerase-I were found to be over expressed in our data analysis, but HSP60, Cyclin B1, and NFKB2 were down regulated. 此外,长期暴露在三氧化二砷的环境中,也已被证实为导致乌脚病及其他癌症的危险因子。
- Apoptosis of keratinocytes was determined by the terminal deoxynucleotidyl transferase end-labeling(TUNEL)assay. The expression of Bax,Bcl-2 and Caspase 3 was evaluated by immunohistochemistry. 采用末端脱氧核苷酸转移酶介导的dUTP缺口末端标记技术(TUNEL)检测角质形成细胞的凋亡状况,同时采用免疫组化法检测角质形成细胞表达凋亡相关蛋白Bax、Bcl-2和Caspase 3的情况。
- HEK293 cell was chose to study the kidney damage of cadmium and to explore the significance of caspase 3,Bcl-2 and AIF(apoptosis inducing factor)in the apoptosis of cells in- duced by cadmium. 本课题研究了氯化镉(CdCl_2)诱导HEK293细胞(人胚胎肾细胞系)的凋亡,初步探讨了凋亡过程中Caspase-3、Bcl-2的变化和凋亡诱导因子(AIF)的转移以及它们的意义。
- Keywords sulfur mustard;lymphocyte;caspase 3;apoptosis; 硫芥;淋巴细胞;胱氨酸蛋白酶-3;凋亡;
- Keywords hypoxia ischemia;neonatal rat;caspase 3;DNA damage; 关键词缺血缺氧;新生大鼠;半胱天冬酶3;DNA损伤;
- Keywords cilostazol;cerebral ischemia;phosphodiesterase 3 inhibitor; 西洛他唑;脑缺血;磷酸二酯酶3抑制剂;
- Keywords intracerebral hemorrhage;apoptosis;Caspase 3;rat;collagenase; 脑出血;细胞凋亡;半胱氨酸蛋白酶;大鼠;胶原酶;
- Keywords Caspase 3 protein;cerebral ischemia reperfusion injury;cell apoptosis; 3蛋白;脑缺血再灌注损伤;细胞凋亡;
- Keywords Bilirubin;Lung injury;Caspase 3;Reactive oxygen species;Apoptosis; 胆红素;肺损伤;半胱氨酸天冬氨酸蛋白酶3;活性氧;细胞凋亡;