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- Whooping cough is a serious respiratory disease caused by Bordetella pertussis. 百日咳是一种由百日咳杆菌引起的严重的呼吸系统传染病，百日咳疫苗是预防百日咳最有效和最经济的手段。
- Whooping cough is a highly infective acute disease on upper respiratory tract caused by Bordetella pertussis. 急性上呼吸道传染病-百日咳，系由百日咳菌所传播的。
- Each SJL mouse was injected s. c. in the abdominal wall with PLP139-151, Mycobacteria H37RA and CFA, and Bordetella pertussis bacilli. 材料和方法:1、应用PLP139-151抗原、福氏佐剂和结核杆菌腹部皮下注射雌性SJL/J小鼠,并且尾静脉注射百日咳杆菌,诱发EAE小鼠动物模型,在免疫后观察60天,每天进行称重和行为学评分。
- Methods An IBI model was induced by injection of bordetella pertussis suspension (BPS) via the left internal carotid arteries of the rats. 方法向大鼠左颈内动脉注射百日咳杆菌悬浮液（0.;2ml/kg体重），诱发感染性脑损伤模型。
- Pertussis toxin (PTX) is an exotoxin produced by Bordetella pertussis, known tohave adjuvant properties that induce Th1 responses. 百日咳毒素具有提升Th1细胞免疫反应的生物学作用,使疾病的低敏感动物品系转变为疾病的敏感型。
- The rats in group A were sensitized by injection of ovalbumin (OA) together with aluminum hydroxide and Bordetella pertussis as adjuvants. A组大鼠用卵蛋白(OA)辅以百日咳杆菌菌苗和氢氧化铝为佐剂注射致敏。
- In adults who have had previous infection with Bordetella pertussis or immunization against it, a persistent cough may be the only symptom. 以前有过百日咳杆菌感染或免疫接种的成人，持续性咳嗽可能是仅有的症状。
- Beside Group A,egg albumin was injected into the abdominal cavity plus the method to kill Bordetella pertussis,to create asthma model in the rats. 除A组外 ,采用腹腔注射卵白蛋白和灭活百日咳杆菌的方法 ,制成大鼠哮喘模型。
- Bordetella pertussis toxin S1 mutant was successfully expressed and purified,which laid a molecular immunological foundation of developing candidate antigen of pertussis vaccine. 成功表达并纯化了百日咳毒素S1亚单位突变体,为研制百日咳疫苗候补抗原的相关分子免疫学研究奠定了基础。
- Pertussis is an acute infectious disease of the respiratory system,which is mainly caused by Bordetella pertussis and found in non-immunised children of developing countries. 百日咳是主要由百日咳杆菌引起的一种传染性强的急性呼吸系统疾病,主要见于发展中国家未接种相应疫苗的儿童。
- Objective:To understand the antibody level of immunization against Bordetella pertussis in healthy population and in puerperal, and provide a timely scientific basis for immunization strategy. 目的:了解乌鲁木齐市健康人群及产妇针对百日咳的血清特异性IgG抗体水平,为制定免疫策略和防治措施提供科学的依据。
- Methods Full length of S1 and Prn genes of three vaccine strains were amplified by PCR. The PCR amplicons were sequenced after being cloned into PGEM-T easy vector and the results were compared with those of Bordetella pertussis strains in GenBank. 方法分别克隆疫苗株的S1和Prn基因至PGEM-Teasy载体、进行测序,并与GenBank中收录的百日咳杆菌S1和Prn蛋白基因序列进行比较、分析。
- Methods Ovalbumin (OVA) together with aluminum hydroxide and Bordetella Pertussis was injected intraperitoneally to immunize SD rats and two weeks later 1% OVA was inhaled to challenge them for consecutive 7 days to mimic allergic airway inflammation. 方法 用鸡卵清白蛋白 (OVA)腹腔注射一次致敏SD雄性大鼠,同时佐以氢氧化铝和百日咳杆菌, 2周后雾化吸入 1%25的OVA进行激发,连续激发 7天,成功制作大鼠过敏性气道炎症模型。
- The ratsingroup A were sensitized by injection of ovalbumin (OA) together with aluminum hydroxide and Bordetella pertussis as adjuvants, followed by aerosolized OA challengetwo weeks later. 组大鼠用卵白蛋白辅以百日咳杆菌菌苗和氢氧化铝为佐剂注射致敏,2周后雾化吸入卵蛋白激发哮喘;
- Infection due to Bordetella pertussis 百日咳博代菌感染
- Fermental cultivation of Bordetella pertussis immunogens 百日咳杆菌有效免疫原的发酵培养
- Keywords Bordetella pertussis toxin;S1 subunit;mutants;vaccine; 关键词百日咳杆菌毒素;S1亚单位;突变体;疫苗;
- Keywords Bordetella pertussis;Pertussis toxin S1 subunit;Immuno protection; 百日咳杆菌;百日咳毒素S1亚单位;免疫保护;
- "Caused by the Bacterium Bordetella pertussis, it initially resembles a cold with a short dry cough. " 致病菌为百日咳博尔德氏杆菌,潜伏期一周,类似普通感冒,伴有短促的干咳。
- Studies on Isolation,Purification and Biological Properties of the 69KDa outer Membrane Protein of Bordetella Pertussis 百日咳杆菌69KDa外膜蛋白的分离纯化及生物学特性研究
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