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- 5-HT1受体亚5-HT1 receptor subtype
- 目的 观察柴地合方对慢性应激抑郁模型大鼠大脑皮层 5 HT1受体和 5 HT2 受体功能的影响 ,探讨其抗抑郁作用可能的机制。Objective To observe the effects of Chaidi Integrated Formula (CIF) on the functions of cerebral 5-HT_1 and 5-HT_2 receptors in the rat model of depression due to chronic stress and to investigate the possible anti-depressive mechanism of CIF.
- 方法 应用大鼠慢性应激模型慢性给药 ,取动物大脑皮层组织 ,采用放射配基结合法测定皮层 5 HT1受体和 5 HT2 受体的最大结合率 (Bmax)和平衡解离常数(Kd)。Method First,the rat model of depression due to chronic stress was chronically given CIF,and the cortices of the model rats were then separated for detecting the B_ max and K_d of 5-HT_1 and 5-HT_2 receptors by radioligand binding assay.
- AMPA受体亚单位GluR2在大鼠局灶性脑缺血不同时期表达及其机制研究Study on AMPA receptor gluR2 expression and mechanisms at various recirculation times following focal ischemia in rats
- 目的:研究三七总皂甙对脑出血大鼠前脑兴奋性氨基酸受体AMPA受体亚基GluR2表达的作用。Objective: To investigate the effects of Panax notoginseng saponins on expression of excitatory amino acid receptor GluR2 subunit of AMPA receptor in the rat forebrain after intracerebral hemorrhage(ICH).
- 宾夕法尼亚Pennsylvania
- 欧亚大陆Eurasia
- 柴地合方可以降低应激大鼠大脑皮层 5 HT1、5 HT2 受体的数目 ,这可能是其抗抑郁作用机理之一。CIF can decrease the numbers of 5-HT_1 and 5-HT_2 receptors in the cortices of the rats with depression due to chronic stress,which may be one of the anti-depressive mechanisms of CIF.
- 酰亚胺imide
- 宾夕法尼亚大学University of Pennsylvania
- 10是5的倍数。10 is a multiple of 5.
- 方法 :用原位杂交的方法测定AY 9944大鼠癫?模型在失神样?性发作时GABAB 受体亚单位GBR1amRNA在鼠脑的表达。Methods:AY 9944 absence seizure model is developed by abdomenal injection of a cholesterol biosynthesis inhibitor AY 9944 to neonatal Lon Evan hooded rats. In situ hybridization is applied to detect GABA B receptor subunit GBR1a mRNA in rat brain of absence seizure.
- 应用免疫组织化学技术观察了大鼠神经系统内 5 -羟色胺 1A受体亚型 ( 5 -HT1 AR)免疫阳性结构的分布。Immunocytochemical staining technique by using specific antibody against 5-HT 1A receptor subtype (5-HT 1A R) was used to observe the distribution of 5-HT 1A R immunoreactivity in the rat nervous system.
- 欧亚风情Eurasian flavor
- 5辆救火车仅过1小时就把火势控制住了。Five fire engines brought the blaze under control in just over an hour.
- 乔治亚州Georgia
- 5除10得2。5 goes into 10 twice.
- 二甲基亚砜DMSO
- 积雪达5英尺。Snow accumulated to a depth of five feet.
- 约书亚Joshua
