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- Secondly, they also directly targeted TG2 with a tiny molecule known as small interfering RNA tailored to shut down expression of the protein. 第二种方法是直接以TG2为靶点,用一种小分子作为裁剪过的小干扰RNA,阻断蛋白的表达。
- Purpose: To construct cellular model of depressed expression of CSB gene by small interfering RNA and investigate of depressing CSB expression on cell growth and radiosensitivity. 目的:研究RNAi(RNA interference)对CSB表达的抑制作用,构建CSB表达抑制的细胞模型及探讨CSB的生物学功能。
- Objective To investigate the suppression of MDR1 and P-glycoprotein induced by small interfering RNA and the restoration of sensitivity to chemotherapeutic drugs in multidrug-resistant hepatocellular carcinoma cell line Bel7402/5-Fu. 目的:研究小片段RNA干扰对肝癌耐药细胞系Bel7402/5-Fu中多药耐药基因(multidrugresistance1,MDR1)及其蛋白产物P-gp表达的抑制作用和逆转其耐药性的效果。
- Role of human leukocyte antigen-G small interference RNA in a choriocarcinoma cell line 小分子干扰RNA对绒毛膜癌细胞人类白细胞抗原G基因表达的影响
- Induction of murine colon carcinoma apoptosis by small interference RNA targeted to Survivin 核糖核酸干扰抑制生存素表达诱导小鼠结肠癌细胞凋亡
- Chemo-synthesized small interfering RNA 化学合成小分子干扰
- small interfering RNA targeting Racl Racl-siRNA
- Keywords recombinant Adeno-Associated Virus (rAAV);hypoxia inducible factor (HIF);small interference RNA (siRNA);ascorbate;proliferation;apoptosis; 重组腺相关病毒;缺氧诱导因子;小干扰RNA;抗坏血酸;增殖;凋亡;
- Does miRNA stimulation of translation raise a possible complication, and opportunity, in using miRNAs and small interfering RNAs as therapeutics? 把微小RNA和小RNA干涉用于治疗学中,微小RNA的翻译刺激可以带来一些困难或者可能性吗?
- The project identified about 21,000 genes and allowed commercial companies to produce "small interfering RNAs," which can selectively block the action of one gene at a time. 这个项目确定了21000个基因,而且允许商业公司生产小分子干扰RNA片段,可以选择性的一次阻止一个基因。
- small interference RNA 小干扰RNA
- !Small interference RNA 小干扰RNA
- Small interference RNA (siRNA) 小干扰RNA
- Small interference RNA(siRNA) 小分子干扰RNA
- Vector expression strategy and expression cassette of small interfering RNA in mammalian RNA interference 哺乳动物RNA干扰中小干扰RNA载体表达策略及其表达盒
- Effects of small interfering RNA specific for Her-2 gene on biological behavior of ovarian carcinoma cell 针对Her-2基因的小分子干扰RNA对卵巢上皮性癌细胞生物学行为影响的研究
- Silencing effect of amyloid precursor protein triggered by small interfering RNA 小干扰RNA对人淀粉样前体蛋白基因的沉默作用
- Interference RNA(iRNA) is not only a powerful tool for gene,but also a mehtod to relieve pathology by specific controlling gene. 干扰RNA不仅是基因功能研究的一种工具,同时也成为一种通过特异调控基因达到减轻病理的手段。
- Inhibition of ovarian cancer growth by small interfering RNA targeting X-linked inhibitor of apoptosis gene X染色体相关凋亡抑制蛋白的小分子干扰RNA对卵巢上皮性癌细胞生长的影响
- Knokdown of Survivin Expression by Small Interfering RNA Induce Apoptosis in Human Osteoscoma Cell Line U-2OS RNA干扰凋亡抑制基因survivin表达及对骨肉瘤细胞系U-2OS相关生物学特性的影响