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Inhibitory effects of recombinant adnovirus carrying wild type PTEN gene on endometrial carcinoma cells: an in vitro study 携带野生型PTEN基因的重组腺病毒治疗子宫内膜癌的体外研究
Experimental Studies on Therapy for Endometrial Carcinoma with Recombinant Adenovirus Carrying Wild Type PTEN Gene(Ad-PTEN) 携带野生型PTEN基因的重组腺病毒（Ad-PTEN）治疗子宫内膜癌的实验研究
Treatment of endometrial carcinoma by recombinant adenovirus vector containing wild type PTEN cDNA: an in vivo study 携带野生型PTEN基因的重组腺病毒治疗子宫内膜癌的体内研究
It would show the same capacity as the wild type. 其能力与野生型相同。
Phenotypically wild type yeast may be produced. 有可能产生野生种表现型的酵母菌.
Methods:The plasmid pcDNA3 containing the wild type p16 gene and neo gene was used in the transfection experiment. 方法：采用pcDNA3质粒进行转染，该质粒含有野生型P16基因片段和新霉素抗性基因。
It would show much higher capacity compared to the wild type. 其能力较野生型高。
It would show much lower capacity compared to the wild type. 其能力较野生型低。
ObjectiveTo study the effects of wild-type PTEN gene on the invasion ability of glioma c ells. 目的观察转入野生型 PTEN基因的胶质瘤细胞体外侵袭力改变 ,探索 PTEN基因对胶质瘤细胞影响方式。
The mechanism is possibly that dysfunction of hMLH1 gene brig about the down regulation of PTEN gene expression. PTEN和hMLH1蛋白表达也会影响胃癌的部分生物学行为,其机制可能是hMLH1基因功能缺陷导致PTEN基因表达下调。
The constructed wild type p21 gene promoter driven luciferase repo rter plasmid is used to transfect ECV304 cells to express luciferase protein sta bly and reliably. 构建的野生型p21基因启动子驱动的荧光素酶报告基因载体,转染ECV304细胞后能够表达荧光素酶蛋白,具有稳定和可靠性能。
To investigate the mutation and methylation of PTEN gene in laryngeal squamous cell carcinoma (LSCC). 摘要目的研究喉鳞状细胞癌（简称鳞癌）蛋白酪氨酸磷酸酶(PTEN)基因突变和启动子甲基化状况。
We optimized the codon usage of wild type HPV 16 L1 gene according to the codon bias of mammalian,and synthesized the full-length optimized L1 gene,named mod. 首先按照哺乳动物密码子偏好对野生型HPV16 L1基因进行改造并合成优化基因;命名为mod.;HPV16L1。
Objective To detect the expression and point mutation of PTEN gene in bladder cancer. 目的检测抑癌基因PTEN在膀胱癌组织中的表达和突变情况。
PCR analysis showed that the CMO gene was transferred into tobacco. Relative electronic conductivity demonstrated less membrane damage in transgenic plants than in the wild type. PCR初步证明外源CMO基因已转入烟草中,转化烟草膜的相对电导率明显低于对照,说明盐胁迫下转基因烟草的膜结构所受损伤小于对照。
If there's more of the enzyme, the PTEN gene seems to do a shoddier job of keeping an eye on keeping cancer at bay. PTEN基因可通过阻止癌症相关细胞过度增殖和诱导肿瘤细胞死亡来抑制肿瘤。
The wild type and mutants SMI Cy/Pm,SMI Cy/+,and vg/vg were investigated. 我们对野生型和突变型SM_1Cy/Pm,SM_1Cy/+和+/Pm进行了研究。
PTEN gene as a apoptosis factorPTEN gene can restrain tumor occurrence by increase cell apoptosis rate except inducing the block of cell cycle. PTEN基因作为凋亡因子除了上述的细胞周期阻滞作用外，PTEN基因增加细胞的凋亡率亦起到抑癌作用。在缺失 PTEN基因的小鼠细胞中导入过表达的 PTEN基因能增加细胞对紫外照射、热休克、辐射诱导的凋亡的敏感性。
GTT, ITT and BMD showed no difference between wild type and mutant mice. BMD检测亦显示该小鼠在基础状态下无骨密度低下的现象。
Conclusion: PTEN gene transfection combined with L-OHP has obvious inhibitory effect on cholangiocarcinoma cell line in vitro. 结论：PTEN基因转染生物治疗联合奥沙利铂化疗对人胆管癌细胞生长具有显著的抑制作用。