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- The DNA repair capacity, as measured by UV-induced unscheduled DNA synthesis (UDS) of splenic lymphocytes from inbred BALB/c male mice, was observed after injection of different doses of 235UO2F2 into the caudal vein. 应用紫外线诱导的非程序DNA合成 (UDS) 检测,观察浓缩铀(235UO2F2)内污染对小鼠脾淋巴细胞DNA损伤修复的影响。
- unscheduled DNA repair 程序外DNA修复
- The effect of concentrated H. pylori culture supernatant (CHCS) on unscheduled DNA synthesis (UDS) in human gastric mucosal cells was studied. 本实验以布氏肉汤旋转培养法制备幽门螺杆菌提取液,观察其对胃粘膜细胞非程序DNA合成的影响。 结果表明幽门螺杆菌提取液可诱导胃粘膜细胞的UDS。
- The study was to assay the unscheduled DNA synthesis (UDS) of human lymphocytes in 21 male workers occupationally exposed to lead. 本文以人外周血淋巴细胞非程序DNA合成(UDS)为观察指标,对职业接触铅的21名男工进行了测试。
- It also indicates that TBA-DNA adducts can be partly eliminated by DNA repair. 这表明,TBA与小鼠肝/肺DNA加合物在小鼠体内能得到一定的修复。
- Methods:Sperm abnormality test, sister chromatid exchange(SCE) test in mouse spermatogonia and unscheduled DNA synthesis(UDS) test in mouse sperms were used. 方法:采用小鼠精子畸形试验、精原细胞姐妹染色单体互换试验和小鼠精子非程序DNA合成试验。
- The damaging effect of four cigarette smoke cundensates(CSC)on freshly isolated lung cells fromrats was studied with the unscheduled DNA synthesis test (UDS). 用程序外DNA合成试验(Unscheduled DNA Synthesis,UDS)研究了四种市售香烟的烟雾冷凝物(Cigarette Smoke Condeinsate,CSC)对新鲜分离的大鼠肺细胞的DNA损伤作用。
- AIMS To assess the effect of concentrated Helicobacter pylori culture supernatant (CHCS) on cell kinetics and unscheduled DNA synthesis (UDS) in rat gastric mucosa. 目的 观察Hp代谢物对大鼠胃粘膜细胞动力学和非程序DNA合成的影响。
- Methods Sperm abnormality test, Chromosome aberration of spermatogonia and unscheduled DNA synthesis (UDS) test in male mouse reproductive cells were used in the study. 方法采用小鼠精子畸形试验、精原细胞染色体畸变试验和小鼠精子非程序DNA合成(UDS)试验。
- AIM To study the stimulatory effect on DNA synthesis and unscheduled DNA synthesis (UDS) in splenic lymphocytes induced by low dose enriched uranium 235 U. 目的:研究了低剂量浓缩铀对脾淋巴细胞DNA合成和UDS的刺激效应。
- Cancer genetics, somatic mutagenesis, DNA repair, genomics and molecular medicine. 肿瘤发生的遗传机制;体细胞突变的发生机制;DNA修复,基因组学与分子医学。
- It is caused by an inherited weakness in one gene that controls DNA repair in other genes. 这是因为某种基因比较脆弱,使得DNA无法修复其他基因。
- AIM To study if there are different effects of 9 enantiomers of clausenamides on aflatoxin B_1(AFB_1)-induced unscheduled DNA synthesis(UDS) injury and glutamic-pyruvic transferase(GPT) release of isolated rat hepatocytes in vitro. 目的研究9种光学活性黄皮酰胺类化合物体外对黄曲霉毒素B1(AFB1)引起大鼠肝细胞非程序性DNA合成(UDS)损伤和谷丙转氨酶(GPT)释放的保护作用有无差异。
- At the same time, cerebral ischemia can activate a complex network of DNA repair tocounteract neuronal DNA damage. 然而缺血在导致DNA损伤的同时,还激活自身的DNA修复系统。
- We calculated lymphocyte post irradiation viability ratio to detect the defection of DNA repair after DN... 即基因修复缺陷可能是帕金森病发病机制的重要环节。
- Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. 聚(ADP -核糖)依赖的DNA修复调节的染色质重塑酶ALC1。
- DNA repair pathways can enable tumor cells to survive DNA damage induced by anti-tumor drugs such as alkylating agents. DNA损伤修复能够使肿瘤细胞耐受化疗药物造成的DNA损伤而存活,因此,调节某种特殊的DNA修复路径可以增强化疗药物的疗效。
- P63 may also co-ordinate DNA repair in eggs with fewer than three breaks, says Dr McKeon. P63可能在卵细胞三次分裂以前对DNA的修复起到协调作用,McKeon称。
- The activity of DNA repair enzyme reduction may involve the mechanism of apoptotic neuron death after ischemia/reperfusion. (2)大鼠脑缺血/再灌注后缺血区神经元凋亡与神经元DNA修复酶活性下降有关。
- PCNA also plays an important role in the DNA repair of neuron,gliocyte proliferation,and cell apoptosis after cerebral ischemia. 脑缺血后出现神经元细胞DNA修复、胶质细胞增生以及细胞凋亡等,PCNA在其中发挥了重要作用,因此受到人们的广泛关注。