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- uniparental inhcritance 单亲性状遗传
- This unambiguously proes that the transplanted uniparental cells could produce hematopoietic stem cells. 这毫无疑问的证明了移植单系干细胞可以生成造血干细胞。
- One issue in using uniparental ES cells for tissue transplants is their durability and safety. 使用单系胚胎干细胞进行组织移植中的问题便是其耐用性和安全性。
- In their current paper, Dr.McLaughlin and colleagues tested the functionality of uniparental ES cells in adult tissues. 在他们最近的文章中,McLaughlin博士和同事测试了单系胚胎干细胞在成熟个体组织中的功能性。
- Howeer, uniparental ES cell research faces the biological hurdle of genomic imprinting, in which specific gene expression patterns are dictated by the parental origin. 然而,单系胚胎干细胞研究面临着基因组印迹的生物学障碍,即特殊的基因表达模式受原始亲代的控制。
- Uniparental cells only hae the imprinting marks for one parental type (or "from one parent") with unknown consequences if harested and transplanted into adults. 单系细胞只有来自一个亲代的印迹标记类型(或来自一个亲代)并且在繁殖并移植到成年个体后可能带来未知的后果。
- K.John McLaughlin and colleagues report on their success in using uniparental embryonic stem cells to replace blood stem cells in mice. JohnMcLaughlin博士和同事报告了利用单系胚胎干细胞替换小鼠的血液干细胞取得了成功。
- The scientists found that uniparental ES cells, regardless of parent-of-origin, were able to functionally reconstitute the entire hematopoietic system of adult mice. 科学家发现单系胚胎干细胞,不管其亲代来源,可以在功能上重建成年小鼠的整个造血系统。
- They can, howeer, generate "uniparental" embryonic stem cell lines.Uniparental embryos with two maternal sets of chromosomes are known as parthenogenetic. 但是,他们可以产生“单系”胚胎干细胞系,带有母系的两组染色体的单系胚胎被称为单性生殖。
- Since uniparental ES cells are not deried from iable embryos, their haresting and use sidesteps many of the ethical concerns that plague traditional ES cell therapies. 既然单系胚胎干细胞不是从可繁育的胚胎中获得,它们的收集和使用可以避开许多困扰着传统胚胎干细胞治疗的伦理学关注。
- Furthermore, the scientists were also able to grow progenitor blood cells in culture from uniparental ES cells, and upon transplant into irradiated adult mice, show that these cells contribute, long-term, to the function of their hematopoietic system. 此外,科学家还能够利用单系胚胎干细胞在培养基中培育血液祖细胞,在移植入辐射照射的成年小鼠后,发现这些细胞对造血系统功能产生长期的作用。
- McLaughlin's group were able to maintain animals for oer 12 months with entirely uniparental blood and were able to rescue irradiated mice with bone marrow transplants from these animals. McLaughlin的小组能够使动物完全依赖单系血细胞存活12个月以上,并且通过骨髓移植挽救受辐射的小鼠。
- Uniparental Disomy and Genetic Diseases 单亲遗传与遗传病
- Maternal uniparental disomy for chromosome 7 母源第7号染色体单亲双体
- chironomous tentans uniparental inheritance 摇蚊单体遗传
- uniparental inheritance that prevents pollen transmission of foreign DNA; 母系遗传方式可防止基因扩散;
- Keywords Prader-Willi Syndrome;uniparental disomy;obesity;genomic imprinting;linkage analysis; 普拉德-威利综合征;单亲二体;肥胖;基因组印记;连锁分析;
- The researchers took a two-step approach: First they injected uniparental ES cells into wild-type blastocyts to generate chimeric animals; 研究人员采取了两步骤的方法:首先,他们将单系胚胎干细胞注入野生型的胚细胞培育嵌合体动物;
- uniparental 单性生殖的.
- uniparental embryo 单亲胚