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- There is often more hypomethylation than hypermethylation of DNA during tumorigenesis and tumor progression. 在肿瘤的发生、发展过程中,DNA低甲基化比高甲基化更为常见。
- These processes are observed during ontogenesis, tumor progression, ischemic disease or physical training. 这些过程可在个体发育，肿瘤进展，局部缺血性疾病或体检中发现。
- These processes are obsered during ontogenesis, tumor progression, ischemic disease or physical training. 这些过程可在个体发育，肿瘤进展，局部缺血性疾病或体检中发现。
- Overexpressions of p 53 and C erbB 2,C ras,C myc have some effects on carcinogenesis,tumor progression and prognosis of patients with GCT. p53及C－erbB2、C－ras、C－myc的表达对卵巢粒层细胞瘤的发生、发展及患者预后有一定的影响。
- With regard to tumor progression, BCG was also statistically superior to epirubicin (Peto OR=1.70, 95%CI=[1.16, 2.49], P=0.006). 在预防疾病进展方面;卡介苗同样优于表柔比星(PetoOR=1.;70;95%25CI=[1
- Aim:To investigate the plasma and tumor tissue neuropeptide Y (NPY) concentration in patients with pituitary adenoma in relation to tumor progression. 目的:研究垂体腺瘤患者血浆和肿瘤组织中的神经肽Y(NPY)浓度与垂体腺瘤的关系。
- DNA hypomethylation plays an important role in tumorigenesis and tumor progression mainly through influences chromosome stability. 在肿瘤的发生、发展过程中,DNA低甲基化比高甲基化更为常见。
- Staveley O,Carroll K,Sotomayor B,et al.Induction of antigene specific T cell anergy:an early event in the course of tumor progression[J].Proc Nati Acad Sci USA,1998,95 (3):1178. 蒋朱明;王秀荣;韦军民;等.;低氮低热量肠外营养与传统氮热量肠外营养对术后病人血糖、感染相关并发症、住院时间、费用等影响的比较[J]
- To identify differentially expressed genes is an important step to better understand the molecular mechanisms in the tumorigenesis and tumor progression of HCC. 为了更进一步瞭解肝细胞癌肿瘤发生与肿瘤进行过程的分子机制，分析并且辨别差异性表现的基因是非常重要的步骤。
- During the waiting time, 14 patients experienced minimal change, which did not fulfill the definition of tumor progression according to official oncological criteria. 在等待移植的阶段，14例患者有细微改变，但未打到官方肿瘤学对于肿瘤发展的标准。
- The primary endpoint was objective response rate(ORR), and the second endpoints were the durative time of remission(DTR), time of tumor progression(TTP), time of treatment failure(TTF), safety assessment and adverse events. 主要终点指标是客观 肿瘤缓解率(ORR),次要终点指标是肿瘤缓解持续时间(DTR)、肿瘤进展时间(TTP)、肿瘤治疗失败时间(TTF)、安全性评估 和毒副反应。
- Objective: To investigate the expression and distribution of matrix metalloproteinase 9(MMP 9) in gastric mucosa with different morphology and to elucidate its association with tumor progression. 目的 :检测基质金属蛋白酶（ matrix metalloproteinase 9,MMP－ 9）在各类人胃粘膜中的表达频率，并观察其分布特点及其与胃癌发生和发展的关系。
- BACKGROUND & OBJECTIVE: Peptidyl-prolyl cis/trans isomerase Pin1 is prevalently overexpressed in human cancers. Up-regulation of Pin1 elevates the expression of Cyclin D1, and plays an important role in tumorigenesis and tumor progression. 背景与目的:肽基脯氨酰顺反异构酶Pin1在人类多种肿瘤中过表达,Pin1过表达可增强CyclinD1表达,在肿瘤发生发展中起重要作用。
- Though 30 base pair deletion of Epstein-Barr virus LMP1 may not be an important pathogenetic step in extranodal nasal type NK/T-cell lymphoma, it may play some role in tumor progression. 不能简单地将LMP1缺失型作为结外鼻型NK/T细胞淋巴瘤的致病因素,但也不能完全否定其促进该淋巴瘤演进的作用。
- Tumor progression occurred in four patients; of these four, one patient developed hydrocephalus requiring a ventriculoperitoneal shunt, two showed neurological deterioration, and one 4-year-old boy died of tumor progression. 4名患者肿瘤恶化；这4人中，1人出现需要进行脑室腹膜分流术的脑积水，2人出现神经方面的退化，1名4岁的儿童死于肿瘤恶化。
- Docetaxel, when combined with cisplatin and 5-FU(DCF), proved to be superior to the standard cisplatin plus 5-FU(CF) regimen in terms of response rate, time to tumor progression, and overall survival. 依据有效率，到肿瘤进展的时间，和总的生存时间，多希紫杉醇与顺铂和5-FU联合(DCF)方案已证明优于顺铂加5-FU标准(CF)方案.
- Our studies also show that MCM2 and CCNB1, which may be potential biomarkers involved in hepatocarcinogenesis and tumor progression, may serve as promising molecular targets for HCC therapy. 我们的研究同时表明，MCM2和CCNB1是与肝癌的发生发展相关的潜在的生物学标记物，它们有希望成为肝癌治疗的分子靶点。
- Objective:To analyze the relations between serum levels of TF and TAOP in patients with cancer, and investigate the function of TF and TAOP levels during the tumor progress. 分析癌症患者血清中转铁蛋白与总抗氧化状态的关系,以探索转铁蛋白与总抗氧化状态在肿瘤形成过程中可能的作用。
- As the tumor progresses, the numbers of H/RS cells increase, while the background cells decrease. 随着病变发展H/RS细胞的数量增加，而背景细胞数目减少；
