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- Xu: It will become a tumor antigen. 徐：它会变成一种肿瘤抗原，
- Methods:Human TSN,inactivated TSN and tumor antigen were prepared. 方法 :制备人肺腺癌A5 4 9细胞的TSN、灭活TSN和冻融抗原 ;
- Tumor antigen specific CTLs may prevent metastasis in the LCI-D20 model and prolong the survival time. 肿瘤抗原特异性CTL可以预防LCI-D20模型肝癌发生转移,延长动物存活时间。
- Objective To study the immune response of dendritic cells (DC) modified with tumor antigen and SEB to transplanted tumor in nude mice. 摘要目的研究结肠癌患者外周血树突状细胞(DC)体外诱导后在裸鼠体内的抗癌效应。
- Methods The tumor antigen peptides from 4T1 breast cancer cells were acquired by freeze thawing method and HSP70-4T1 peptides complex was reconstructed in vitro. 方法冻融法获取BALB/C小鼠4T1乳腺癌细胞抗原肽,体外重组HSP70-4T1抗原肽复合物。
- Objective To investigate antitumor effects induced by dendritic cells (DCs) pulsed with complex of tumor antigen from elemene-combo tumor cell vaccine-heat shock protein 70 of BCG (HTA-HSP70BCG). 目的观察体外构建的榄香烯复合瘤苗抗原-卡介苗热休克蛋白70复合物(HTA-HSP70BCG)诱导的树突状细胞疫苗的抗肿瘤效应。
- It will become a tumor antigen. 它会变成一种肿瘤抗原。
- METHODS: BMDCs were stimulated by CpG ODN in combination with tumor antigen (TAg). The expression of CD80 on BMDC surface was analyzed by FCAS. Level of IL-12 (p70) in supernatants of BMDC culture was detected by ELISA. 方法 :CpGODN联合肿瘤抗原 (TAg)体外刺激BMDC ,流式细胞术检测受刺激BMDC表达CD80的阳性率 ,ELISA检测受刺激BMDC分泌IL - 12 (p70 )的水平 ,MTT法检测活化BMDC刺激T细胞的增殖能力 ,联合CpGODN和TAg体内预激小鼠获得CTL ,检测CTL对肝癌细胞株Hca-F的特异性杀伤作用。
- Methods Tumor antigen peptides from elemene-combo Hca-F cell (HTA) combined with HSP70BCG into HTA-HSP70BCG in vitro. DCs were induced in medium with GM-CSF and IL-4 and pulsed with HTA-HSP70BCG, HTA and HSP70BCG, respectively. 方法来源于小鼠的肝癌Hca-F榄香烯复合疫苗的抗原(HTA)与卡介苗来源的HSP70(HSP70BCG)在体外构建成HTA-HSP70BCG复合物,用GM-CSF和IL-4诱导树突状细胞(DCs),分别用HTA-HSP70BCG、HTA和HSP70BCG对其冲激。
- The tumor specific CTL was generated form activated autologous T cell by DC vaccine loaded with tumor antigen, and the killing activity of CTL to CT26 cells was tested by the lactate dehydrogenase (LDH) release assay in vitro. 负载肿瘤抗原的DC疫苗激活同源T淋巴细胞产生细胞毒性T淋巴细胞(CTL),采用乳酸脱氢酶(LDH)4h释放法检测CTL在体外对CT26细胞的杀伤活性;
- It is critical in antitumor immune responses that the APCs (antigen presenting cells) present tumor antigens(Tags) to T cells to activate immune system to eradicate tumor cells. 抗肿瘤免疫应答中关键的一步是抗原递呈细胞(APC)将肿瘤抗原递呈给T细胞，激活机体的免疫系统来清除肿瘤细胞。 树突状细胞(DC)是目前认为功能最强的抗原递呈细胞，也是APC的一个独特的亚群。
- The adoptive transfer technique uses a small fragment of each patient's melanoma to grow T-cells in vitro targeting specific tumor antigens. 采用转移技术利用每个患者黑色素瘤中的极少部分，体外培养特异肿瘤抗原T细胞。
- Recent researches have demonstrated that the ATPase domain of HSP70 and the tumor antigenic peptide that binds to Hsp70 were the crucial parts eliciting tumor-specific immunity. 最近的研究表明HSP70携带的小肽及其ATPase结构域是HSP70抽提物激活肿瘤特异性免疫反应的关键。
- Progress in identification and application of human tumor antigen 人类肿瘤抗原的鉴定及应用进展
- Keywords EBV;B lymphocyte;Tumor antigen;Antigen presenting; 淋巴细胞;肿瘤抗原;抗原提呈作用;
- Keywords tumor antigen;tumor immunotherapy;vaccines; 肿瘤抗原;肿瘤免疫治疗;疫苗;
- A malignant tumor originating in glandular tissue. 腺癌起源于腺性组织的恶性肿瘤
- The surgeon operated on her for a tumor. 医生为她的肿瘤开刀。
- The attraction between an antigen and an antibody. 化合力抗原和抗体之间的相互吸引
- The surgeon operated on him to remove the tumor. 外科医生给他做手术以切除肿瘤。
