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- The application and the safetyof the electroporation in transdermal drug delivery are also introduced. 电致孔可显著提高药物的经皮吸收,有望用于多肽和蛋白质类生物大分子药物的透皮给药。
- Conclusion:Transdermal drug delivery system has broad market and development perspective. 结论透皮给药系统具有广阔的市场和开发前景。
- The characteristic of an electroporation apparatus for transdermal drug delivery is discussed in the paper. 本文分析了一种经皮给药电穿孔仪的性能。
- Objective:To promote development of transdermal drug delivery system and present the internal and external advancement of recent years. 目的:介绍近年来国内外透皮给药的研究进展,以促进透皮给药系统的开发。
- The transdermal drug release performance was mainly investigated and the factors which affect mechanical properties were also evaluated. 对一些影响压敏胶贴剂力学性能的因素进行了考察,并重点研究了载药压敏胶贴剂经皮释放规律。
- Objective In order to study the tissue distribution of Praziquantel(PZQ) and the pharmacokinetics after transdermal drug delivery. 目的研究透皮给药后吡喹酮在小鼠体内的组织分布及药代动力学。
- With the development of transdermal drug delivery preparation, the development of TCM cataplasma takes peop1e attention. 摘要随着近年来经皮给药制剂的迅猛发展,中药巴布剂的发展也倍受关注。
- Base on the requirement of hydrophilic pressure-sensitive adhesives (PSA) in transdermal drug delivery systems (TDDs),a hydrophilic polyurethane PSA were prepared. 结果表明,该聚氨酯压敏胶贴剂具有良好的药物控释能力,适用于经皮给药系统。
- The results indicated that the hydrophilic polyurethane PSA prepared show good transdermal drug release properties, which suit for the TDDs application. 结果表明,该聚氨酯压敏胶贴剂具有良好的药物控释能力,适用于经皮给药系统。
- The cutaneous microdialysis and its application in transdermal drug delivery system, including pharmacokinetics, bioavailability and bioequivalence evaluation are reviewed. 离子透入法;;投药,皮肤;;微透析;;生物利用度;;综述;;治疗等效
- Aim To illustrate the non-equilibrium properties of drug permeation through stratum corneum (SC) to provide theory and method for transdermal drug delivery. 摘要目的阐述药物在经角质层渗透过程中的非平衡态特性,为经皮给药技术提供理论和力法。
- The aim of the present study was to establish a noninvasive technique of transdermal drug iontophoresis to assess cutaneous endothelial function in healthy volunteers. 目的内皮细胞功能障碍与高血压等多种疾病有关,本研究用激光多普勒-离子电渗透技术测定了健康人内皮细胞功能并对其方法学进行评价。
- Historically,developments in transdermal drug delivery have been incremental,The transdermal drug delivery(TDD) mainly depend on skin barrier its molecular size and hydrophilic/hydrophobic properties. 药物的透皮给药主要受到皮肤障碍、药物的分子量和亲水/油性等因素的影响。
- To observe the enhancement of the diffusion rate of capsaicin permeating through the skin by screening several complex accelerators for transdermal drug delivery system(TDS) containing capsaicin. 通过对辛香中药的研究筛选辣椒碱巴布剂的透皮吸收促进剂,提高辣椒碱的透皮扩散速率。
- Aim To prepare triamcinolone-acetonide-acetate (T AA)-loaded solid lipid nanoparticles (SLN) carbomer gel with tripalmitin glycer ide (TPG), and investigate their characteristics and transdermal drug delivery. 目的 以醋酸曲安奈德 (TAA)为模型药物 ,以三棕榈酸甘油酯为脂质材料制备醋酸曲安奈德固体脂质纳米粒(SLN)卡波姆凝胶 ,考察其特性以及药物经皮渗透性能。
- Themechanisms,experimental devices and the influence factors of electroporation are reviewed.The application and the safetyof the electroporation in transdermal drug delivery are also introduced. 本文对电致孔法的透皮促渗机制、影响因素以及安全性进行了讨论,并介绍了有关实验装置及其在透皮给药中的应用。
- Liposomes as carriers for external and transdermal drug delivery system and the interaction betweenliposomes and stratum corneum, experimental techniques, clinical applications are reviewed. 对脂质体作为外用透皮吸收药物的载体及其与角质层的相互作用、检测技术及临床应用等方面进行综述。
- By disrupting the stratum corneum structure and create pathways allowing transport of macromolecules, microneedles array can improve the transdermal drug delivery and increase the efficiency. 传统的被动式经皮给药严重受限于皮肤角质层的阻碍,利用微针阵列破坏角质层可改善皮肤对药物的渗透性,大大提高经皮给药效率。
- The nurse diluted the drug with saline water. 护士用生理盐水把药加以稀释。
- The druggist put in a full stock of drugs. 那位药商进了一大批药品。