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- This is an example of c-myc positivity in a carcinoma.This oncogene acts via DNA transcriptional activation. 此癌基因通过使正常原癌基因数百次的复制产生一种能驱使细胞非调节性生长的蛋白。
- Objective:To assay the transcriptional activation effect of prohibitin in yeast two hybrid system. 目的:检测抗增殖蛋白在酵母双杂交系统中是否具有转录自激活作用。
- These variants change the conformation and stability of nucleosome to facilitate transcriptional activation or deactivation, DNA repairing, heterochromatin formation, and others. 这些变体通过改变核小体的空间构象和稳定性，决定基因转录的激活或沉默，DNA的修复，染色体的异染色化等。
- Acetylation of lysine residues of core histone N-terminal domains has been found correlatively associated with transcriptional activation in eukaryotes. 真核细胞组蛋白N端赖氨酸残基的乙酰化与基因的转录激活有关。
- Results The protein expressed by the plasmid which had a correct reading frame, had no transcriptional activation and could interact with a known coactivator PNRC. 结果该质粒有正确的阅读框,其表达蛋白不具有自主转录激活作用,与已知核受体辅活化子PNRC有明显的相互作用。
- The transcriptional activation activity of GR was evaluated through method of relative activity of luciferase. 相对荧光素酶活性法检测gr转录激活功能的变化。
- The transcriptional activation function of GR was evaluated through the detection of relative luciferase activity after dexamethasone treatment. 相对荧光素酶活性法检测地塞米松作用后gr转录激活功能的变化。
- H3-K79 methylation plays a role in DNA repair and transcriptional activation, and the extent and biological significance of histone demethylation will surely attract great attention. 组蛋白H3第79位赖氨酸的甲基化与防止基因失活和DNA修复有关。与此同时，组蛋白的去甲基化也受到更为广泛的关注。
- AML 1 gene abnormalities, including both chromosome translocation and mutation (point mutation, insertion, deletion mutation, et al), which lead to the lost of transcript activation, are general in acute leukemia. 在急性白血病中常见AML1基因结构异常，包括平衡易位及突变(如点突变、插入或缺失突变等)，导致AML1的转录活性丧失，提示此基因功能缺失在急性白血病的发生及发展中起着重要作用。
- AIM: To clone fibronectin (FN) promoter and identify its transcriptional activity combined with SV40 enhancer. 目的:克隆纤维连结蛋白(FN)启动子和检测其转录活性,并初步研究增加SV40增强子对其转录活性的影响。
- Ho, T.-Y., C.-Y.Hsiang and T.-J.Chang. 1996 DNA requirements for transcriptional activity of pseudorabies virus. 中华民国兽医学会暨台湾省畜牧兽医学会八十五年度联合学术论文发表会。
- We described the HSF structure and th e regulation of its transcriptional activity. 本文叙述了热激因子的结构及热激因子的活性调节方面的研究动态。
- Title： Cloning, expression and transcriptional activity of Bm-mof, an MYST histone acetyltransferase gene in the silkworm, Bombyx mori L. 关键词：家蚕;MYST组蛋白乙酰转移酶;克隆;序列分析;表达谱
- Covalent modifications of histone tails play a key role in the regulation of chromatin structure and control of transcriptional activity. 染色体组蛋白的共价修饰在调节染色体结构,控制基因的转录等方面发挥重要的作用。
- In addition, PCP-2 can not only maintain the dephosphorylation state of P-catenin but also antagonize p-catenin/T cell factor (TCP) dependent transcriptional activity. PCP一2下调野生型和组成激活型p一catenin转录活性，该作用依赖于 PCP一2磷酸
- The chromatin remodeling and histone acetylation were associated with transcription activation. 真核基因活化与染色质的重建及组蛋白的乙酰化相关。
- The ArJ-mediated enhancement is orientation-independent. In the 5th instar larvae, MH treatments enhance the transcriptional activity of the promoter combination. 在家蚕五龄蚕体内不同发育阶段BmHSC70-4/hr3启动子组合的转录活性有所波动，到熟蚕期达到最高，这与BmHSC70-4启动子一致，说明hr3只是增强转录活性，并不改变特性。
- The high transcriptional activity of hTERT gene promoter in MCF7 cell indicates its potential utility as a novel candidate for transcriptional targeting of breast cancer. hTERT启动子在乳腺癌MCF7细胞中具有很强的特异性,为进一步开发肿瘤的特异性基因治疗奠定实验基础。
- Transcriptionally active regions are replicated first. 转录活跃区域先复制。
- XU LZ,ZHOU XY,ZHU WP,et al.Detection of peripheral blood lymphocyte subtype and analysis of the rDNA transcriptional activity[J].China Oncology,1999,9(4):265-268. [5]许良中;周晓燕;朱伟萍;等.;外周血淋巴细胞亚群检测及其rDNA转录活性分析[J]
