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- AIM To study the preparation and stability of sinomenine liposomes. 目的:优选青藤碱脂质体的制备方法,并研究其稳定性。
- Objective: To establish an HPLC method for the determination of entrapment efficiency of sinomenine liposomes. 目的:建立青藤碱脂质体包封率的测定方法。
- Objective: To investigate the activities of transdermal penetration of sinomenine liposome patch. 摘要 目的:研究青藤碱脂质体贴剂的经皮渗透行为。
- Methods: The sinomenine liposome patches and the same patches without liposome were used as model drugs.The transdermal penetration of the two patches was respectively tested in vitro and in vivo. 方法:以青藤碱脂质体贴剂与不含脂质体的普通贴剂为模型药物,分别采用离体和在体经皮渗透试验进行比较研究。
- Keywords sinomenine liposomes;entrapment efficiency;sephadex filtration;mini-column centrifugation;dialysis; 青藤碱脂质体;包封率;凝胶过滤法;微柱离心法;透析法;
- sinomenine liposomes 青藤碱脂质体
- Keywords Penetration enhancers;Sinomenine liposomes;Liposome patch;Transdermal penetration; 促渗剂;青藤碱脂质体;透皮贴剂;经皮渗透;
- Methods The C ring in sinomenine was modified. 方法以青藤碱为先导物,对C环进行结构改造。
- Impact of rat skin stratum corneum on transdermal absorption characteristic of Sinomenine Liposome Patch 大鼠皮肤角质层对青藤碱脂质体贴剂透皮吸收的影响
- Keywords sinomenine liposome patch;transdermal absorption;ambiexponent equation; 青藤碱脂质体贴剂;透皮吸收;双指数方程;
- Keywords Sinomenine Liposome Patch;tape stripping;stratum corneum (SC);transdermal absorption; 青藤碱脂质体贴剂;胶带剥离;角质层;透皮吸收;
- Objective To optimize the prescription of tea tree oil liposomes. 目的优化制备茶树油纳米脂质体的处方。
- Objective To prepare and optimize formulation of ATRA liposomes. 目的通过制备不同配方全反式维甲酸脂质体,对处方进行优化。
- sinomenine liposome patch 青藤碱脂质体贴剂
- Aim To provide basic data for the synthesis of new sinomenine derivatives. 目的为定向设计合成高效低毒的新一代青藤碱类药物提供线索。
- Objective: To prepare sinomenine gel and study its skin penetration in vitro. 目的:制备青藤碱凝胶剂,研究其透皮渗透性能。
- Results Sinomenine could induce apoptosis o f synoviocytes in CIA rats. 结果青藤碱组CIA大鼠滑膜细胞的凋亡数明显增加。
- Aim Io provide basic data for the synthesis of new sinomenine derivatives. 摘要目的为定向设计合成高效低毒的新一代青藤碱类药物提供线索。
- Hydrostatic Pressure Effects on Transport in Liposomes and Red Cells. 静水压力对脂质体、红细胞运输的影响。
- OBJECTIVE To determine the trap efficiency of liposomes using Sephadex. 目的考察用葡聚糖凝胶法测定脂质体包封率的影响因素。
