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- Keywords minichromosome maintenance protein;replication;replicative helicase; 微小染色体维持蛋白;复制;复制解螺旋酶;
- replicative helicase 复制解旋酶
- Is that picture original one or replicative one? 那幅画是原作还是复制品？
- Helicase Any of a group of enzymes that catalyze the unwinding of double-stranded nucleic acids such as DNA, using energy from ATP. 解螺旋酶（蜗牛酶）：一组可以催化象DNA这样双链核酸解螺旋的酶，由ATP提供能量。
- The vasa gene is an important member in DEAD-box protein family, the Vasa protein is an ATP-dependent RNA helicase. vasa基因是DEAD-box家族的重要成员,其蛋白具有依赖ATP的RNA解旋酶活性。
- Step 2: The intervening single strand DNA of 28 nts is then removed after DNA helicase unwinds the DNA. 步骤1：核苷酸切除修复复合体识别损伤，然后在3’端距离损伤位点5个核苷酸处形成一个切口；在5’端距离损伤位点23个核苷酸处形成另一个切口；
- For example, helicase and telomerase, are drug targets for controlling virus replication and cancer cell survival. 我们期待综合蛋白质结构与动态的资讯将有助了解基本生化过程的机制及设计酵素抑制剂.
- The inhibitory action of A 6 and ACV on HSV 1 revealed mainly at the replicative stage of viral proliferation cycle. 结果还表明A6 和ACV对HSV1 的抑制作用主要表现在病毒增殖周期的复制阶段。
- A second \'deliberate\' mechanism is called replicative senescence or cellular senescence. 第二个\\'故意\\'的机制被称为复制性衰老或细胞衰老。
- But this hypothesis fails because replicative senescence is far older than cancer. 但这一假说失败了，因为复制衰老比癌老得多。
- Many invertebrates experience replicative senescence, though they never die of cancer. 许多无脊椎动物经历复制衰老，虽然它们从来没有死于癌症。
- An unresolved problem of the clamp loader was that it had to "flip up" when it loads the ssDNA emerging from the helicase with a clamp. 一个与夹子装载系统有关的不确定问题，是当其装载单链DNA时，会将其连同一个夹子“上抛”。
- One of its jobs is to pry apart the two strands of DNA (via helicase action) to allow the RNA polymerase to get access to the DNA bases. 它的其中一个工作，是探查两条分开的DNA链（通过螺旋运动方式），以使RNA聚合酶可以与DNA碱基相接触。
- The measurement of telomere length can give an insight into the replicative history of the cells in question. 端粒酶长度的测量技术给正在研究中的细胞的复制史提供了一个新角度。
- The museum made some replicative bronze wares according to its collection and displayed them to public recently. 据悉，安徽省博物馆根据自己的馆藏，成功仿制出一批高仿真青铜器，并对外展出。
- Strand displacement of this intermediate by a DNA helicase channels the reaction towards synthesis-dependent strand annealing (SDSA). DNA链通过DNA解旋酶通路反应置换这个中间体，对合成依赖链退火（SDSA）。
- The helicase genes of Infectious spleen and kidney necrosis virus (ISKNV) and TFV were characterized, sequence analysed. 应用生物信息学软件对鳜鱼传染性脾肾坏死病毒（ISKNV）和虎纹蛙病毒（TFV）的解旋酶（helicase）基因进行了序列结构分析，并探讨了该基因的功能结构域。
- Among these viruses, the most effective one is the Elb-55Kda deficiented replicative virus(ONYX-015) developed by the American ONYX Pharmacy Company. 其中最引人注目的肿瘤特异性增殖型病毒是美国ONYX药物公司研究的E1b55Kda缺陷的增殖型腺病毒（ONYX－015）。
- The study of the relationship between telomere-related factors and cell replicative senescence contributes to elucidate the mechanism of aging. 近年来的研究发现,端粒长度的缩短是造成细胞复制性衰老的原因,而端粒的长度受端粒相关因子的调节。
- However, CNHK300 exhibited attenuated replicative ability and killing effect in normal fibroblast cell line than wtAd5 did. CNHK300病毒和紫杉醇联合应用，较同样剂量的两者单独应用,细胞存活率明显下降。
