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- Expression of mismatch repair gene hMSH2 in human adenocarcinoma of cervix and its clinical significance. 错配修复基因hMSH2在宫颈腺癌组织中的表达
- Mismatch repair gene defects are recently identified in hematopoietic malignancies, leukemia and lymphoma cell lines. 错配修复基因缺陷是最近在造血系统恶性肿瘤,白血病和淋巴瘤细胞株中被发现的。
- Objective To construct the pEGFP|C1|K vector,an eukaryotic expression plasmid of DNA double|strand break(DSB) repair gene hKu 70 antisense RNA and provide experimental material for the studies of hKu 70 gene function and toxicology. 目的 构建人DNA双链断裂 (DSB)修复基因hKu70反义RNA真核表达载体pEGFP C1 K ,为以后的hKu70基因功能和毒理学研究提供实验材料。
- Objective: The aim of this research was to obtain the distribution of genotypes frequencies and the allelic frequencies of DNA repair gene X-rag repair cross-complementing groups 3(XRCC3) Thr241Met of the Han population in Sichuan. 目的:研究DNA修复基因X线修复交叉互补基因3(XRCC3)Thr241Met位点多态性在四川汉族人群的分布,并与其它种族比较其分布特点。
- Conclusion The results suggest that antitumor effect of SarCNU in EMT positive tumor is satisfactory even though the tumor exhibits DNA repair gene expression, specifically MGMT and ERCC1-6. 肿瘤细胞的EMT和DNA修复基因MGMT以及ERCC1 6的表达均为阳性。 结论 在EMT阳性的肿瘤 ,即使具有DNA修复基因表达 ,SarCNU仍然具有良好的抗肿瘤作用
- O6-Methylguanine-DNA methyltransferase(MGMT)is an important DNA repair gene in human cells.It plays an important role in resisting cellular DNA damage induced by alkylating agents. O6甲基鸟嘌呤DNA甲基转移酶(MGMT)是细胞中一种重要的DNA损伤修复酶,它在抵御烷化剂所致的细胞突变和死亡中起重要作用。
- Emergence of cancer relates not only to activation of oncogene, inactivation of anti-oncogene and metabolic enzyme gene, but also to DNA repair gene which plays an important role in stability of DNA. 摘要癌症的发生不但与癌基因激活、抑癌基因失活、代谢酶基因异常有关,与修复酶基因可能也有关系,因而也日益受到关注。
- Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) methods were used to measure DNA damage repair gene XPC and folate metabolism enzyme gene MTHFR polymorphisms. 对照组选自同期居住在扬中境内的居民,与病例按性别和年龄组进行成组频数匹配,要求身体健康,无恶性肿瘤及胃和十二指肠溃疡病史,征得同意后采集静脉血并进行流行病学问卷调查。
- Emergence of cancer relates not only to activation of oncogene,inactivation of anti-oncogene and metabolic enzyme gene,but also to DNA repair gene which plays an important role in stability of DNA. 癌症的发生不但与癌基因激活、抑癌基因失活、代谢酶基因异常有关,与修复酶基因可能也有关系,因而也日益受到关注。
- Some DNA repair genes are irreversibly damaged by smoking, and smoking also switched off genes that help combat lung cancer development. 而吸烟将不可逆的破坏一些DNA修复基因,并关闭一些对抗肺癌的基因。
- Conclusion A certain number of HNPCC families can be benefited from the genetic screening for mutation of the mismatch repair genes. 结论错配修复基因的突变筛选可帮助、指导临床对HNPCC家系进行严密监控。
- Objective To explore germline mutation frequencies and features of mismatch repaired gene MSH6 in persons with different kinds of colorectal cancer. 摘要目的了解错配修复基因MSH6在不同形式大肠癌人群中的种系突变频率及特征,提供真正的突变热点。
- DNA Damage Repair Gene and Genetic Susceptibility DNA损伤修复基因与遗传易感性
- Human DNA mismatch repair gene (hMMR) 错配修复基因
- She turned the chair on its side to repair it. 她把椅子翻转过来修理。
- I have to wait in for the repair man. 我只得在家里等修理工。
- I'm all at sea; I've no idea how to repair cars. 我手足无措,不知道怎样修理汽车。
- John managed to repair his car by himself. 约翰设法独力修理自己的汽车。
- The lorry was damaged beyond hope of repair. 卡车严重损坏,已无修复的希望。
- Dust the repair to prevent adhesion to outer cover. 清整修补处以防与外胎粘连。