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- The M receptor agonist pilocarpine was similar to the effects of ACh. M受体激动剂毛果芸香碱能产生与ACh相似的效应。
- Objective To investigate the effect of doparnine receptor agonist piribedil on dopamine transporter. 目的研究常用抗帕金森药多巴胺受体激动剂吡贝地尔(舒达)脑多巴胺转运体的影响。
- Clinical treatment of PD includes dopamine replacement such as L-DOPA and D_2 dopamine receptor agonist. 目前临床仍以替代治疗为主,左旋多巴和D_2受体激动剂能改善PD症状,但不能阻制疾病发展,这使人们对PD治疗的认识由单纯替代疗法逐渐转向保护中脑DA能神经元。
- Rotigotine is a non-ergolinic dopamine receptor agonist available as a patch for once-daily use. 罗替戈汀是现有非二氢麦角碱多巴胺受体激动剂中可作为每日一次使用的辅助药物。
- Rotigotine is a non-ergolinic dopamine receptor agonist aailable as a patch for once-daily use. 罗替戈汀是现有非二氢麦角碱多巴胺受体激动剂中可作为每日一次使用的辅助药物。
- The citrated whole blood is tested at the basal and TRAP (Thrombin Receptor Agonist Peptide) activated states. 柠檬酸化的健康的血被测试在基础并且捕捉(凝血酶感受器官收缩筋肽)被激活的状态。
- A brief discussion is also given about the pr ospects of nicotinic receptor agonist used as non-opiate analgesics. 从地棘蛙素全合成研究、类似物制备、药理学行为和构效关系等几方面介绍了国际上研究的热点,并对今后的研究动向进行了讨论。
- The effects of receptor agonist and antagonist on hypnotic activity of melatonin were studied in the paper. 观察不同受体激动剂或拮抗剂对褪黑素催眠作用的影响。
- Objective: To study the protecting effect of delayed preconditioning with A1 selective adenosine receptor agonist in donor heart preservation. 目的:探讨腺苷A1受体激动剂延迟预处理对大鼠心脏的保护效果。
- The competition curves of inverse BDZ receptor agonist DMCM was illustrated in a biphasic way by a computer model of two sites. 反相激动剂DMCM竞争结合曲线亦具有双位点结合特性。
- Endorphins, a known substances produced in brains is an opioid receptor agonist which the brain produce in the presence of pain stimulus. 如果你一连几天、一天几次进行实验:诱发某人身感疼痛,再用吗啡为他止疼,到最后一天,悄悄用盐水取代吗啡,你会发现,此时盐水也能止痛。
- As a high-selective 5-HT1D receptor agonist, sumatriptan is mainly used as an emergency medicine in the treatment of migraine and cluster headache. 舒马曲坦为具有高度选择性的5-HT1D受体激动剂,主要用作偏头痛和丛集性头痛发作的急救药。
- Our results demonstrated for the first time that Spd, the dopamine D1 receptor agonist -D2 receptor antagonist, decreased the reinforcing efficacy of cocaine. 我们的研究首次发现,多巴胺D1受体激动- D2受体拮抗剂左旋千金藤啶碱降低可卡因的奖赏效应;
- Effect of 5-HT 1A receptor agonist buspirone (Bus) on the anxiolytic action of BDZ receptor agonist diazepam (DZP) was examined in two different animal anxiety models: Vogel's drinking conflict test (VT) and social interaction (SI) test. 应用大鼠 Vogel冲突饮水实验和群居接触焦虑模型 ;观察丁螺环酮 (Bus)对地西泮抗焦虑作用的影响 .
- Effects of selective dopamine 1 (DA 1) receptor agonist fenoldopam and dopamine 2 (DA 2) receptor agonist propy1 butyl dopamine (PBDA) on the cAMP generation system in renal, pulmonary, mesenteric and femoral arteries of rabbits were studied. 实验观察了选择性多巴胺 (DA)DA1受体激动剂fenoldopam与DA2 受体激动剂propy1 butyl dopamine (PB DA)对兔肾动脉 ,肺、肠系膜动脉和股动脉环磷酸腺苷 (cAMP)产生系统的影响。
- Methods In vitro transfered and cultured renal tubular cells AT2 receptor agonist CGP - 42112A in different doses were diffused, then cell apoptosis was analyzed by TUNEL and flow cytometry. 方法 通过取新生大鼠肾小管上皮细胞体外培养,传代后加入不同浓度AT_2受体兴奋剂CGP-42112A,在不同时间用流式细胞仪测定凋亡细胞比值,并结合TUNEL分析。
- Results:A microinjection of dopamine or apomorphinc, a dopamine receptor agonist, resulted in an evident increase in blood pressure and heart rate, but haloperidol (halo) can reduced them mildly. 注射多巴胺受体拮抗剂氟哌啶醇则引起血压和心率的降低。
- P2X receptor agonist activated currents of SCG neurons were greatly potentiated after myocardial ischemia; A-317491 could inhibit the currents activated by P2X receptors agonist. 心肌缺血后P2X受体激动剂在SCG神经元激活电流增大,P2X3受体特异性拮抗剂A-317491可抑制P2X受体激动剂激活的电流。
- nicotinic acetylcholine receptor agonist 烟碱型乙酰胆碱受体激动剂
- Background Ergot-derived dopamine receptor agonists, often used in the treatment of Parkinson's disease, have been associated with an increased risk of valvular heart disease. 背景:有发现表明常用于治疗帕金森病的麦角洐生的多巴胺受体激动剂可增加发生瓣膜性心脏病的风险。
