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- Roles of receptor tyrosine kinases, integrins, and Shc. 外文期刊 Mechanotransduction in response to shear stress.
- The epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases have close connection with the initiation, progression and progn osis of various malignancies. 表皮生长因子受体(EGFR)家族的受体酪氨酸激酶与多种恶性肿瘤的发生、发展及预后等密切相关。
- Moreover, non-cytotoxic agents such as small molecules targeting receptor tyrosine kinases and intracellular signaling pathways have been used in the clinical field. 替莫唑胺及亚硝基脲类药物耐药性得到了部分解决以及非细胞毒性药物如酪氨酸激酶抑制剂及细胞间信号传导通路抑制剂在临床中的应用。
- Sorafenib, a novel, oral multi-kinase inhibitor, targets on serine/threonine and receptor tyrosine kinases of the tumor cells and vasculature; blocks the signal transconduction and inhibits tumor growth. 摘要索拉非尼是首个口服多激酶抑制药，靶向作用于肿瘤细胞和肿瘤血管上的丝氨酸和（或）苏氨酸及受体酪氨酸激酶，阻断信号传导，抑制肿瘤生长。
- The inhibitor of VEGF receptor tyrosine kinase was introduced in detail. 详细介绍了VEGF受体酪氨酸激酶抑制剂的研究进展。
- Sunitinb is a novel multitargeted receptor tyrosine kinase inhibitor. 苏尼替尼是一种新型的多靶点酪氨酸激酶抑制剂。
- Objective:To explore the mutation of receptor tyrosine kinase ( RET ) gene in sporadic medullary thyroid carcinoma. 目的:研究散发型甲状腺髓样癌酪氨酸激酶受体基因(RET)的突变情况。
- Angiopoietin acts on Tie-2,which is a receptor tyrosine kinase specifically expressed on endothelial cells. 作用于内皮特异受体酪氨酸激酶酪氨酸激酶受体2。
- We are interested in the identification of novel components in Drosophila EGF receptor tyrosine kinase (RTK) signal transduction pathway. 我们主要的兴趣在于用遗传学及分子生物学的方法来研究果蝇的胚胎发育过程。
- All these actions of VEGF are mediated by receptor tyrosine kinase, vascular endothelial growth factor receptor (VEGFR). 所有这些作用都是通过血管内皮生长因子受体信号转导通路实现的。
- Receptor tyrosine kinase (RTK), a membrane receptor superfamily with intrinsic protein tyrosine kinase activity, has many members and complicated signal transduction pathways. 摘要受体酪氨酸激酶是一个具有内在酪氨酸蛋白激酶活性的膜受体超家族，成员众多，信号转导通路复杂多样。
- Objective To construct the antisense nucleic acid eukaryotic expressing vector of the cDNA sequence encoding the transmembrane domain of receptor tyrosine kinase RON (RON-RTK) gene (RONm). 目的构建RON基因跨膜区段(RONm)的反义核酸真核表达载体。
- In addition, the invention also relates to a method which adopts the compound and the drug combination and can prevent, control and treat cancer by inhibiting EGFR receptor tyrosine kinase. 此外，本发明还涉及了应用这类化合物、药物组合物以及通过抑制EGFR受体酪氨酸激酶来预防、控制和治疗癌症的方法。
- Abstract： Brain-derived neurotrophic factor （BDNF） can increase the excitability of hippocampus by activating its receptor tyrosine kinase B and then result in temporal epilepsy. 摘要： 脑源性神经营养因子（BDNF）激活其受体酪氨酸受体激酶B，使海马兴奋性增高，从而促使颞叶癫痫产生。
- Keywords receptor tyrosine kinases;signal transduction;potassium channels;modulation; 受体酪氨酸激酶;信号转导;钾通道;调节;
- Sorafenib,a novel,oral multi-kinase inhibitor,targets on serine/threonine and receptor tyrosine kinases of the tumor cells and vasculature; 索拉非尼是首个口服多激酶抑制药,靶向作用于肿瘤细胞和肿瘤血管上的丝氨酸和(或)苏氨酸及受体酪氨酸激酶,阻断信号传导,抑制肿瘤生长。
- Receptor tyrosine kinase inhibitor 受体酪氨酸激酶抑制剂
- Tyrosine kinases are involved in the pathogenesis of most cancers. 酪氨酸激酶参与了大部分肿瘤的发病。
- receptor tyrosine kinases 受体酪氨酸激酶
- Sunitinib: a novel multitargeted receptor tyrosine kinase inhibitor 新型多靶点酪氨酸激酶抑制剂苏尼替尼的研究进展
