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- In this study, we investigated its metabolism by use of rat liver microsome in vitro. 利用大鼠肝微粒体对新农药多噻烷进行体外代谢研究。
- Antioxidant activities of extractions were determined by chemical methods to produce superoxide free radicals, hydroxide free radicals and lipid peroxide of rat liver microsome. 采用化学方法产生超氧阴离子自由基、羟自由基和小鼠肝匀浆液脂质过氧化体系对提取物进行抗氧化活性检测,研究其清除自由基和抑制脂质过氧化能力的差异。
- In vitro the experimental results showed that fluoride could significantly increase the content of lipid peroxide (LPO) of rat liver microsome, and the lipid peroxidation was antagonized by adding selenium to liver microsomal system simultaneously. 体外实验结果表明,加氟可使微粒体系统脂质过氧化物(LPO)含量显著增加; 同时加硒可结抗氟致微粒体系统的脂质过氧化作用。
- The correlation between peak area of a metabolite and original concentration of Nef in rat liver microsomes solution was significant( r =0.993). 温孵液中代谢产物生成的量与底物Nef的浓度具有良好的相关性(r=0.;993);
- Results and Conclusion : The result s both with and without S9 (rat liver microsomal enzymes) showed that all the samples had no mutagenicity. 结果与结论:经加和不加大鼠肝脏微粒体酶(S9) 两种试验,结果全部受试物均未发现致突变毒性;
- Study on the stereoselectivity of oxidation metabolism of mexiletine enantiomers in rat liver microsome 大鼠肝微粒体中美西律对映体氧化代谢的立体选择性研究
- The metabolism of diphenytriazol was investigated in five kinds of rat liver microsomal incubate pretreated with phenobarbital (PB), dexamethasone (Dex), p-naphthoflavone (BNF), diphenytriazol and control. 方法:l)用CYPIA、CYPZB的两种特征性底物乙氧基异吩恶吟与7一戊氧基异吩恶吟在经不同天数地非三吟处理的鼠肝微粒体中代谢,用荧光仪在激发波长(ex)565nm,发射波长(em)587nln下直接测定代谢物异吩恶吟的生成量。
- Keywords m-nisoldipine;HPLC;rat liver microsome;determination;enzymatic reaction kinetics; 间尼索地平;高效液相色谱法;大鼠肝微粒体;测定;酶促反应动力学;
- rat liver microsome 大鼠肝微粒体
- Enzyme kinetics of genistein metabolism in rat liver microsomes 染料木黄酮在大鼠肝微粒体代谢的酶动力学
- Keywords TM208;Rat liver microsomes;Metabolism;Cytochrome P450 isoform; 大鼠肝微粒体;代谢;细胞色素P450亚型代谢酶;
- Activation of rat liver microsomal glutathione S-transferase by chlorambucil and cyclophosphamide in vitro 苯丁酸氮芥及环磷酰胺对大鼠肝微粒体谷胱甘肽S-转移酶的激活
- Competitive Inhibition from CYP 1A2 in Rat Liver Microsomes by Polychlorinated Biphenyls 多种多氯联苯对大鼠肝细胞微粒体CYP1A2的竞争性抑制作用(英文)
- CHIRAL RP-HPLC ASSAY FOR PROPAFENONE ENANTIOMERS IN RAT LIVER MICROSOMAL INCUBATES AND ITS APPLICATION IN VITRO METABOLISM 手性衍生化-反相高效液相色谱法测定大鼠肝微粒体中盐酸普罗帕酮对映体及其在代谢研究中的应用
- The Bradford method was used to measure the concentration of protein in liver microsome, and activities of cytochrome P450 enzymes were determined by the spectrophotometer method. 测定一月龄至八月龄不同性别的猪,肝微粒体蛋白含量、CYP450含量、CYPb5含量、NADPH-细胞色素C还原酶活性、氨基比林-N-脱甲基酶活性、红霉素-N-脱甲基酶活性和苯胺-4-羟化酶活性。
- Damaging effect on rat liver endothelial cells of tripterine in vitro. 红素对大鼠肝脏内皮细胞的体外杀伤作用。
- The proper conditions for testotesrone metabolism in liver microsome system included substrate concentration, incubation time, pH and incubation temperature. 方法:采用超高速离心法制备大鼠肝脏微粒体,建立体外肝脏微粒体混合酶代谢体系。
- According to recent materials,Introduce liver microsome incubations in vitro,liver cell incubations in vitro,isolated perfused liver and liver slices,respectively. 对近几年的文献资料进行分析、综合、归纳。
- Those workers discuss the evidence for and against several models for microbody biogenesis in rat liver. 这些研究者讨论赞成和反对鼠肝微体生物发生的几种模式的证据。
- The enzymes prepared from pea, rat liver and bovine brain were composed of fewer subunits than the microbial enzymes. 从豌豆、鼠肝和牛脑制备的酶比微生物中的酶包含的亚基少。
