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- quinolone antibiobtics 喹诺酮类抗菌素
- Reason to recommend: the domestic drug industry leading quinolone. 推荐理由：国内喹诺酮类原料药行业龙头。
- AIM To study the thermal stabilities of quinolone drugs and to establish equations for their decomposition kinetics. 目的研究喹诺酮类药物的热稳定性及热降解,建立动力学方程。
- Objective To study whether quinolone agents can penetrate the placenta and what is its level in fetal cartilage. 目的了解孕妇应用喹诺酮类药物是否会影响胎儿的软骨发育。
- Seven determine ways of quinolone kinds of medicament's content was reviewed,Thirty-one references were included. 本文从7个方面对喹诺酮类药物的含量测定方法进行了总结综述.;引用文献31篇
- If there is an allergy to penicillin, physicians should consider azithromycin or a respiratory quinolone. 如果对青霉素过敏，医师们应该考虑阿奇霉素或呼吸喹诺酮。”
- Eleven determination methods of some quinolone drugs are summarized, and the influential factors are discuseed. 对喹诺酮类药物11种含量测定方法进行了综述，并对相关因素作了讨论。
- The combined use of two agents,one quinolone drug plus another antibiotic, was common. 3.;该类药物与其它抗生素的联用仍以二联为主。
- The contents of quinolone medicines such as ofloxacin etc in aqueous solution are analyzed by ion inhibition chromatography. 用离子抑制色谱进行水溶液中氧氟沙星等喹诺酮类药物含量的分析。
- Objective: To know about the matter on the anaphylactic shock caused by quinolone series, so as to provide references for drug application clinically. 目的:了解喹诺酮类药物致过敏性休克的情况,为临床用药的安全性提供参考。
- Objective To improve the synthesis of tetrafluorophthalic acid as an intermediate in preparing quinolone antibacterials. 目的合成喹诺酮类抗菌药中间体四氟邻苯二甲酸,并改进工艺,使之适用于工业化生产。
- Quinolone is known as broad antibacterial spectrum, high potency, no crossing drugresistance with other antibacterial drugs, and easy and low cost to administer. 喹诺酮类药物具有抗菌谱广、菌活性强、药方便,与常用抗菌药物无交叉耐药性、格低等特点。
- The quinolone antibacterial has generated considerable interests in controlling microbe infection since it was firstly applied into clinic practice more than 40 years ago. 摘要喹诺酮类抗生素在临床使用已有40多年，它对人类控制微生物感染产生了巨大的作用。
- Difloxacin is the fluorinated quinolone approved for use in veterinary only. compared to ciprofloxacin,it provided with better pharmacokinetical and pharmacodynamical feature. 二氟沙星属于兽医专用药物，并且有优于环丙沙星的药动学特征，具有良好的应用前景。
- Results The ratio of acinetobacter infection in LRTI was 19.01%,acinetobacters resist in most of the antibiotics except Sulperazon,Imipenem+Cilastatin,quinolone antibiotics. 结果下呼吸道不动杆菌感染率为19.;01%25;除对舒普深、泰能及喹诺酮类抗生素敏感外;此菌广泛耐药。
- Quinolone is known as broad antibacterial spectrum,high potency,no crossing drugresistance with other antibacterial drugs,and easy and low cost to administer. 喹诺酮类药物具有抗菌谱广、抗菌活性强、给药方便,与常用抗菌药物无交叉耐药性、价格低等特点。
- Structural modification is still popular and important in the area of finding novel quinolone antibacterial agents with more potential activity and broad spectrum. 对喹诺酮类化合物进行进一步的结构修饰,以便获得活性更强,活性谱更广的新喹诺酮类抗菌药,仍是抗感染化疗领域近几年的热点领域之一。
- Method: Using the method of agar dilution to measure the MIC of 86 strains clinically isolated Pseudomons aeruginosa with four kinds of quinolone individually and combined with reserpine and verapamil. 方法 :通过琼脂二倍稀释法检测 86株铜绿假单胞菌对四种喹诺酮类药物与利舍平及维拉帕米联用前后的mic值及 86株铜绿假单胞菌对其它常用抗生素的 mic值 ;
- Huang,X., Liu,Z.-X.,"Solid-Phase Synthesis of 4 (1H) ?Quinolone and Pyrimidine Derivatives on a new Scaffold-Polymer-Bound Cyclic Malonic Acid Ester", J. Org. Chem., 2002, 67 (19), 6731-6737. 国家自然科学基金面上重点项目：“丙二酸环酯聚合物试剂参与的杂环化合物固相合成”（2001-2003）。
- The binding characteristics of quinolone antibacterial agent, ofloxacin (OFLX) and ciprofloxacin(CPFX) with catalase(CAT) were studied by fluorescence spectroscopy in aqueous solution. 应用荧光光谱法研究了水溶液中喹诺酮抗菌素氧氟沙星、环丙沙星与过氧化氢酶分子间的结合反应。
