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- Investigate the efftects of exogenous quinolinic acid on acute and subacute animal models of inflammation. 研究外源性给予喹啉酸对动物急性和亚急性炎症模型的影响。
- Objective To explore the effect of estrogen on striatal neurons damage in rats induced by quinolinic acid (QA). 摘要目的探讨雌激素对喹啉酸(QA)所致的大鼠纹状体神经元损伤的影响。
- Objective To investigate the effect of tetradrine(Tet) on the contend of MDA,the activity of NOS and Na~+-K~+-ATP,Ca~(2+)-Mg~(2+)-ATP of primary hippocampi neurons cocultured with quinolinic acid(QA). 目的探讨粉防己碱(Tet)对喹啉酸(QA)诱导损伤的原代海马神经元丙二醛(MDA)、一氧化氮合酶(NOS)及Na+-K+-ATP酶和Ca2+-Mg2+-ATP酶的影响。
- Method In vitro: primary hippocampus neurons were cultured using embryo rat brains, the MTT and the activity of LDH were assayed and the pathology was observed, so as to study the protection of Tet from excitotoxicity induced by quinolinic acid(QA). 方法:离体实验:采用海马神经元原代培养,检测培养神经元的MTT、 LDH活性,并观察其病理形态学改变,来研究Tet对QA损伤的海马神经元的保护作用。
- Method:In vitro: primary hippocampus neurons were cultured using embryo rat brains, the MTT and the activity of LDH were assayed and thepathology was observed, so as to study the protection of Cin from excitotoxicity induced by quinolinic acid(QA). 方法:采用海马神经元原代培养,检测培养神经元的MTT、 LDH活性,并观察其病理形态学改变,来研究Cin对QA损伤的海马神经元是否有保护作用,利用海马神经元损伤细胞模型,通过检测各组神经元的MDA含量、NOS活性、细胞内游离Ca2+浓度及细胞外几种兴奋性氨基酸和抑制性氨基酸含量的变化情况来探讨Cin对QA损伤海马神经元保护作用的相关作用因素。
- IDO has been targeted for neurological disorders: it causes decrease of serotonin level in the brain resulting depression, and it causes the accumulation of neurotoxic quinolinic acid. IDO与神经系统疾病也密切相关,它能降低5-羟色胺的水平而导致抑郁, 也可造成脑中喹啉酸等具有神经毒性的代谢产物的累积;
- Significance of Quinolinic Acid in Inflammation 喹啉酸在炎症进程中的意义探讨
- Keywords GC-MS;quinolinic acid;serum; 喹啉酸;血清;气质联用;
- Concentration of quinolinic acid in rat serum by GC-MS 大鼠血清中喹啉酸含量的气质联用测定
- Keywords hippocampus neurons;Lomerizine;quinolinic acid; 海马神经元;洛美利嗪;喹啉酸;
- Keywords Tetradrine;Quinolinic acid;Hippocampi neurons;Apoptosis; 关键词粉防己碱;喹啉酸;海马神经元;凋亡;
- The invention further provides a novel method for synthesizing di-chlorine quinoline acid oxo by utilizing the novel oxidizer. 本发明还提供了一种利用所述的新氧化剂合成二氯喹啉酸氧化合成工艺的新方法。
- Keywords estrogen;quinolinic acid;Huntington s disease; 喹啉酸;雌激素;亨廷顿病;
- Keywords hippocampus neurons;excitotoxicity;cinnarizine;quinolinic acid; 关键词海马神经元;兴奋毒;桂利嗪;喹啉酸;
- He gave me a taste of his acid wit. 他让我尝到了他敏锐尖刻之机智的滋味。
- Acid irritates the stomach lining. 酸能刺激胃黏膜。
- Acid had pitted the surface of the silver. 酸把银器的表面腐蚀了。
- Keywords autophagy;lysosome;quinolinic acid;NMDA receptors;excitotoxicity; 自噬;溶酶体;喹啉酸;NMDA受体;兴奋性毒性;
- I am doing an experiment of neutralizing acid. 我在做一个中和酸的实验。
- Can Jones beat Smith? That's the acid test. 琼斯能击败史密斯吗?那是个严峻的考验。