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- Compared with the known synthetic routes for pyrrolidine derivatives, our method shows impressive efficiency and high stereoselectivity. 该方法可以同时构建三个手性中心，高度立体选择性地合成syn-anti相对构型的3-(1-羟烷基)-吡咯烷酮。
- METHODS A series of pyrrolidine derivatives were synthesized from L-hydroxyproline,and the neuraminidase inhibitory activities of these compounds were tested using high throughput screening. 方法以L-羟脯氨酸为原料,合成一系列神经氨酸酶抑制剂,并用高通量活性筛选方法检测其对神经氨酸酶的抑制活性。
- Keywords pyrrolidine derivatives;synthesis;characterization; 吡咯烷衍生物;合成;表征;
- Comparative molecular field analysis of pyrrolidine derivatives as MMP-2 inhibitors 吡咯烷类基质金属蛋白酶-2抑制剂的比较分子力场分析
- Keywords pyrrolidine derivatives;matrix metallloproteinaes inhibitors;aminopeptidase N inhibitors;antitumor activity; 吡咯烷衍生物;基质金属蛋白酶抑制剂;氨肽酶N抑制剂;抗肿瘤活性;
- Keywords rational drug design;3D-QSAR;ADMET;matrix metallloproteinaes inhibitors;pyrrolidine derivatives;chemical synthesis;anti-tumor activity; 合理药物设计;3D-QSAR;ADMET;基质金属蛋白酶抑制剂;吡咯烷衍生物;化学合成;抗肿瘤活性;
- pyrrolidine derivatives 吡咯烷衍生物
- The chemistry of petroleum and its derivatives. 石油化学石油及其复合物的化学
- Keywords C60: 1;3 -dipolar cycloaddition: LB film;Pyrrolidine derivative; 偶极环加成反应;LB膜;吡咯烷衍生物;
- Resembling opium or its derivatives in activity. 起鸦片或其衍生物作用的
- It mainly deals in amino acid derivatives, indole, pyrrolidine, piperidine and piperazine series. 主营：氨基酸衍生物系列,吲哚系列,吡咯烷系列、哌啶系列,哌嗪系列。
- Higher derivatives and taylor series. 高阶导数和泰勒级数。
- Derivatives come in two forms: options and futures. 衍生工具有两种：期权和期货。
- WHY ARE THE LUPANINE DERIVATIVES BITTER? 为什么白金雀儿碱的派生物是苦的?
- How can a scientific category have its derivatives? 科学范畴何以能衍生?
- Containing opium or any of its derivatives. 含鸦片或其衍生物的
- Any of several derivatives of this compound. 此类化合物的各种衍生物
- Any of various derivatives of this compound. 吲哚类产品任何一种由这种化合物制造出来的产品
- Many English words are derivatives of Latin words. 许多英语词来自拉丁语。
