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- The data indicate that rhIL 13 enhances the expression of proto oncogene c mpl in Dami Cells. rhIL 13增强了Dami细胞原癌基因c mpl表达 ;
- The product of proto oncogene c Cbl has been proved as a new ubiquitin ligase (E3) of RING finger type for ubiquitin proteasome pathway. c Cbl最近被证明是泛素 蛋白酶体 (ubiquitin proteasome)通路中的一个新的RINGFinger型泛素连接酶 (ubiquitinligase ;E3) .
- Increased expression of proto oncogene c fos plays an important role in the occurence and development of fibrous dysplasia. c?fos 癌基因的过度表达在骨纤维结构不良的发生发展中起重要作用。
- Objective: To investigate the actual role of the proto oncogene product c CBL in the signaling elicited by BCR/ABL oncoprotein. 目的 :探讨原癌基因产物c CBL在P2 10BCR/ABL激发的异常信号转导中的作用。
- Our results suggest that the overexpression of c erbB 1 proto oncogene might be one of the important reasons that can induce keratinocytes of psoriasis to proliferate abnormally. 提示c-erbB-1的过度表达可能是导致银屑病角朊细胞异常增殖的重要原因之一。
- Objective To explore the role of c fos and c jun expression in psoriasis. 目的为了探索c?fos、c?jun与银屑病的关系。
- Objective To explore the characteristics expression c jun and c fos on visual system during monocular deprivation. 目的 了解单眼视觉剥夺 ,c- jun、c- fos基因在视觉发育过程中的表达特性。
- Methods 80 rat tongue specimens were detected for C FOS? C JUN proteins with SABC. 方法 用免疫组化SABC法检测 80例大鼠舌组织标本中C FOS、C JUN蛋白的表达。
- It can be measured the expression of c jun and c fos by using the methods of RT PCR and agarose gel electrophoresis. 应用RT PCR和琼脂糖凝胶电泳方法测定c jun和c fos基因的表达。
- Objective To investigate the effects of tetrandrine (Tet) on the expressions of c fos and c jun mRNA in hepatic fibrotic rats. 目的 探讨粉防己碱 (tetrandrine ,Tet)对肝纤维化大鼠肝组织c fos及c junmRNA表达的影响。
- However,c fos protein level did not change significantly in HG group ( P >0 05). On the other hand,c Jun protein expression increased by 45%. HG组c Fos蛋白水平无明显变化 ,c Jun蛋白则显著升高达 4 5%25。
- Growth hormone could promote growth of intestinal mucosal cell, improve proliferation of epithelial cells and expression of mucosa c jun. 生长激素可减轻TPN大鼠小肠粘膜萎缩改变 ,并促进肠上皮细胞增殖和肠粘膜c jun基因表达。
- There was a higher expression of c jun mRNA and protein in BIU87/A than that in BIU87, but no difference in c fos was found in both cell lines. c jun基因mRNA及其蛋白在BIU87/A的表达均高于BIU87,而c fos基因在BIU87和BIU87/A的表达未见明显差异 (P >0 0 5 ) ;
- Purpose To evaluate the effects of MAPK phosphorylation and the expression of c fos and c jun proteins in hepatocarcinogenesis. 目的 :研究MAPK磷酸化与c fos和c jun蛋白表达在HCC发生中的作用。
- The results showed that intracellular Ca 2+ concentration decreased 69% and 79%,nuclear Ca 2+ /Mg 2+ ATPase activities diminished 21% and 37%,c jun expression decreased obviously. 结果发现,乌贼墨使H22癌细胞内Ca2+浓度分别降低了69%25和79%25,核膜Ca2+/Mg2+-ATP酶活性分别降低了21%25和37%25,c-jun表达明显减少。
- Selenium position might affect the expression of C Fos and C Jun protein of fetal brain and might affect the development of neural system and intelligence. Se的水平可影响胎脑大脑皮层神经元 C- Fos,C- Jun蛋白的表达 ,并进而可能影响胎儿神经系统及智能的发育
- The expression of c fos and c jun protein could be induced by forced swimming and venlafaxine could suppress significantly the accumulated immobility time of forced swimming. 强迫游泳可使大鼠下丘脑和海马内多个核团的c?fos 和c?jun 蛋白表达水平增加,而万拉法新明显缩短了强迫游泳大鼠的不动时间。
- Keywords Proto oncogene protein;\ Gene expression;\ Hypertrophic scar;\ Keloid; 原癌基因蛋白质;基因表达;增生性瘢痕;瘢痕疙瘩;
- The positive correlation was observed between p42/44MAPK and c fos protein expressions, and so did between p Stat3 and c jun, but there was no significant correlation between p42/44MAPK and p Stat3 in HCCs and their surrounding liver tissues. 在HCC和癌旁肝组织中p42/44MAPK和c-fos蛋白表达强度呈正相关; p-Stat3与c-jun蛋白亦呈正相关;
- The c fos, c jun gene expression in cerebral cortex and hippocampus was obviously increased in amygdala kindled rat model, and the positive cell number of fos or jun expression increased significantly ( P < 0.01) . 杏仁核点燃癫?大鼠的皮层与海马c fos、c jun基因表达明显增强 ,阳性细胞数量显著增加。
