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- It is, therefore, feasible to exploit IL-8 promoter to control the replication of oncolytic adenovirus aiming to achieve more tumor-targeted oncolysis for treating NSCLC. 因此,在非小细胞肺癌中以介白素八调控子控制溶瘤腺病毒应可具有更佳的肿瘤专一性与溶瘤效果。
- Keywords Cancer;Biotherapy;Oncolytic adenovirus;Heating;Abscopal effect; 肿瘤;生物治疗;溶瘤腺病毒;热疗;远端效应;
- Keywords oncolytic adenovirus;gene therapy;hepatocellular carcinoma; 裂解型腺病毒;基因治疗;肝细胞肝癌;
- Keywords survivin;human telomerase reverse transcriptase promoter;RU486-regulated system;dominant negative mutant;RNA interference;oncolytic adenovirus;non-apoptotic cell death; 人端粒酶逆转录酶启动子;RU486调控系统;显性抑制突变体;RNA干扰;溶瘤腺病毒;非凋亡性细胞死亡;
- oncolytic adenovirus 溶瘤腺病毒
- oncolytic adenovirus vector 溶瘤腺病毒载体
- An Armed Oncolytic Adenovirus System, ZD55-Gene, Demonstrating Potent Antitumoral Efficacy 2.Resveratrol Induces Autophagy in BEL7404 Human Hepatoma Cells by Upregulation of Beclin 1 一.;携带治疗基因的肿瘤特异性增殖腺病毒ZD55-Gene治疗肿瘤 二
- Here we construct a hTERT and Cox-2 promoter regulated oncolytic virus byreplace the endogenous adenovirus El a and Elb promoter respectively. 为下一步进行腺病毒在293细胞的包装、纯化、以及病毒感染各种肿瘤细胞、病毒感染治疗动物实体瘤模型奠定基础。
- Objective: To evaluate the selectively oncolytic effect of conditionally replicating adenovirus CNHK500 in breast cancer. 目的: 观察选择性增殖腺病毒CNHK500对乳腺癌的特异性杀伤作用。
- Adenovirus mediated angiostatin gene therapy for rat glioma. 重组腺病毒载体介导血管抑素基因治疗大鼠脑胶质瘤的实验研究。
- Adenovirus and parainfluenza virus are common viruses in the community. 腺病毒及副流感都常见于社区。
- Keywords adenovirus;transductional control;oncolytic; 腺病毒;转导调节;溶瘤;
- The patterns of DNA of these viruses are similar to that of enteric adenovirus( EAd). 这些腺病毒DNA的电泳图型类似于肠道腺病毒。
- Tremendous advances have been made in developing oncolytic viruses in the last few years. 近几年溶瘤病毒的研究有很大进展。
- In this review,tumor targeting,killing efficiency,safety and the evaluation of oncolytic viruses therapy are discussed. 文章简要综述了溶瘤病毒肿瘤治疗的靶向性、杀伤性、安全性和疗效监测。
- The initial discovery of the virus' oncolytic properties were limited to only a few types of cancer. 有些典当行甚至集典当、担保、评估、拍卖于一体。按陈先生的话来说,同样的'当'字如今早已有了不同的涵义。
- Adenovirus is the main candidate for expressing and delivering therapy genes because of its intensive tissue tropism. 因其具有广泛的组织亲和性,腺病毒成为表达和传递治疗基因的主要候选者。
- Laboratory tests for three of discharged patients showed adenovirus in 2 and parainfluenza type 3 in one. 三名出院病人的化验显示,其中2名为腺病毒,另一名为副流感3型。
- Objective To characterize the intertype epitopes on human adenovirus (HAdV) hexon. 目的 对人类腺病毒 (adenovirus,AdV)六邻体型间抗原位点的特性进行研究。
- Objective To study the therapy for C6 glioma with therecombinant adenovirus containing angiostatin eDNA (AdhCMV-AGS). 目的:构建重组缺陷型腺病毒血管抑素基因(angiostatin)载体,进行血管抑制基因治疗脑胶质瘤的体内及体外的实验研究。