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- A brief discussion is also given about the pr ospects of nicotinic receptor agonist used as non-opiate analgesics. 从地棘蛙素全合成研究、类似物制备、药理学行为和构效关系等几方面介绍了国际上研究的热点,并对今后的研究动向进行了讨论。
- The researchers identified an area of DNA ariation that seems to alter the function of a nicotinic receptor protein. 研究者发现了改变尼古丁受体蛋白质功能的一DNA变异区域。
- Conclusion : The result s indicated that d-tubocurarine is able to inhibit mammal mitosis by blocking the function of nicotinic receptor. 同时,该化合物还具有影响染色体正常分离的潜在能力。
- AIM: To investigate the mechanism of tricyclopinate, an antagonist of nicotinic receptor, on neuronal nicotinic acetylcholine receptors (nAChR). 目的:观察烟碱受体拮抗剂三环哌酯对烟碱诱发电流的作用。
- central neuronal nicotinic receptor 中枢神经元烟碱受体
- The malfunction of cholinergic and nicotinic receptors may be a mechanism of aneuploid induction. 对胆碱受体功能的研究将有助于探索非整倍体产生的各种机制。
- Local alpha-bungarotoxin-sensitive nicotinic receptors in the nucleus accumbens modulate nicotine-stimulated dopamine secretion in vivo. 伏隔核中的局部阿尔法-金环蛇毒素敏感烟碱感受器在体调制烟碱诱发多巴胺分泌。
- Objective:It is to study the effect of saponins from Anemarrhena asphodeloides Bge(SAaB) on cerebral nicotinic receptors. 目的 :研究知母皂甙 (SAa B)对衰老大鼠脑乙酰胆碱受体的影响。
- Spinosad depolarizes insect neurons by activating nicotinic receptors, causing widespread hyperactivity in the nervous system. 其作用机制是通过激活烟碱型受体使昆虫神经细胞去极化,引起中央神经系统广泛的超活化。
- The effects of nicotinic receptors are so pervasive, in fact, that some of the mechanisms involved are not completely understood. 尼古丁受体作用广泛,因此有些相关机制尚未完全解开。
- "I took two cell lines and checked to see if the cells expressed the nicotine receptor, and I found they did," Chen said. “我提取了两个细胞系来观察检查,看看细胞是否表达尼古丁受体,结果我发现了这一现象,”他说。
- Given the complexity of the neuropsychological systems affected by nicotinic receptors, most of the episodes involving varenicline may never be explained. 由于尼古丁受体所影响的神经心理系统十分复杂,大部份涉及戒必适的状况可能永远都无法解释。
- Keywords desensitization;nicotinic receptor;acetylcholine;choline; 失敏;烟碱样受体;乙酰胆碱;胆碱;
- In a series of lab experiments, Chen and colleagues discovered that certain breast epithelial-like cells produce different subtypes of the nicotine receptor nAChR, as do certain breast tumor cells. 在一系列实验室实验中,陈博士和他的同事发现:某些乳腺上皮样细胞产生不同的尼古丁受体nAChR亚型,同乳腺癌肿瘤细胞有关。
- Keywords Cannabinoid Neuronal nicotinic receptor Whole-cell patch clamp; 关键词大麻素;神经元烟碱受体;全细胞膜片钳;
- Both GABA and nicotinic receptors had been suspected of inolement in nicotine addiction, but these findings strengthen those suspicions. GABA和尼古丁受体也被怀疑与尼古丁成瘾相关,然而以上的发现加强了这一怀疑。
- A sensory receptor that detects warmth. 热探测器测量热量的敏感接受器
- The effects of muscarinic and nicotinic receptor antagonists on compound action potentials in the cochleae of gerbils 毒蕈碱和烟碱受体阻断剂对沙鼠耳蜗复合动作电位的影响
- Keywords Whole cell recording;Nicotinic receptor;Allosteric modulation;Antagonist;Dimethyl tetrandrine iodide; 全细胞记录;烟碱受体;变构调节;拮抗剂;碘化二甲基粉防已碱;
- Nicotinic acetylcholine receptors, a ligand-gated ion c hannels,mediates many important physiological processes.Chronic nicotine admini stration could desensitize nicotinic receptors. 烟碱样受体属于配体门控性离子通道受体,参与调节体内许多生理过程。