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- myostatin MSTN 肌肉生长抑制素MSTN
- Myostatin(MSTN) gene is expressed specifically in developing and mature skeletal muscle,and the expression products of MSTN gene inhibits muscle growth and differentiation. 摘要 双臀基因(MSTN)在发育和成熟的骨骼肌中特异表达,并对肌肉具有负调控作用。
- Double-muscled phenotype of Belgian Blue and Piedmontese beef cattle was caused by mutation of 11bp deletion and substitution of conserved base in bioactive region of myostatin gene(MSTN). “双肌”肉牛品种比利时蓝(Belgian Blue)和皮德蒙特(Piedmontese)分别是由于MSTN3’保守的生物活性区11bp的缺失和保守碱基的点突变所造成的;
- Keywords pig;microsatellite;myostatin gene(MSTN); 猪;微卫星;肌肉生长抑制素基因;
- PHARMACEUTICAL AND biotechnology companies are working on a variety of myostatin inhibitors. 制药界和生技公司正致力发展各种阻断肌肉生长抑制素作用的药剂。
- The potential medicine is designed to inhibit the protein myostatin, which limits muscle growth. 该蛋白药物设计抑制限制肌肉生长的筒箭毒碱蛋白。
- Phylogenetic analysis showed that the myostatin protein is highly conserved during evolution. 这表明黄颡鱼肌肉生长抑制素在进化上是高度保守的。
- The purification of MSTN protein The expressed product was purificated by TALON Single Step columns and the purificated product was detected by SDS-PAGE. 6.;MSTN蛋白纯化 参照TALON Single Step columns试剂盒操作说明书纯化目的蛋白,纯化产物取样进行SDS-PAGE检测。
- This smaller protein, or peptide, essentially caps those docking locations, preventing myostatin from attaching to them. 将这种胜肽注射到小鼠体内,能让小鼠的骨骼肌增厚。
- We also have identified the upregulation of a protein called myostatin, which inhibits protein synthesis and muscle generation. 另外,我们还发现一种称之为mystatin蛋白的表达上调,可抑制蛋白质合成和肌肉形成。
- The first myostatin-blocking drugs to have been developed are antibodies against myostatin, one of which may soon undergo clinical testing in muscular dystrophy patients. 最先开发成功的肌肉生长抑制素的阻断剂,是肌肉生长抑制素的专一性抗体,其中一种很快将进行临床试验,治疗DMD患者。
- Myostatin gene will be an important therapeutic target for muscle- wasting-related disorders, and continues to shed light on the development of animal muscle for animal breeding. 肌肉生长抑制素的研究将为肌肉萎缩等相关性疾病的治疗及动物育种提供新的途径。
- Therefore, the present study was undertaken to explore the possibility of gene targeting in sheep fibroblasts by using myostatin as targeting gene, mAAT as the integrated gene and Neo as mark gene. 为此,本研究以myostatin基因为靶向基因,mAAT基因为目的基因,Neo基因为标记基因,对绵羊体细胞基因敲除进行了一系列探索性的研究。
- Intramuscular fat content was affected by QTLs on chromosomes 5-8, 15, 17 and 28, respectively, and on GGA7, NAB1 and GDF8 (Myostatin) might be the best candidates for further study. 对鸡7号染色体上影响肌间脂肪含量的QTL座位区域进行候选基因分析发现,NAB1和GDF8(Myostatin)可能是最佳候选,而且座位NAB1对另一个座位GDF8有着调控作用,共同影响着肌间脂肪的表现。
- 3'-UTR analysis of myostatin gene Myostatin3′-UTR分析
- 3'-regulatory region of Myostatin gene Myostatin基因3′-调控区
- myostatin gene (MSTN) MSTN基因
- myostatin(MSTN) 肌肉生长抑制素
- MyoStatin (MSTN) 肌肉生长抑制素(MSTN)
- Myostatin (MSTN) gene 肌生成抑制(MSTN)基因
