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- Bre can alleviate myocardial hypertrophy and fibrosis induced by Iso in rats. Bre对Iso引起大鼠心肌肥厚和纤维化具有一定的改善作用。
- Recently people find that cyclosporin A has extremely good effects on the treatment of many diseases such as myocardium hypertrophy, myocardial ischemical reperfusion injury, brain injury and so on. 此外,环孢酶素A在防治心肌肥大、心肌缺血再灌注损伤、脑损伤等疾病都显示了极好的疗效。
- Conclusion Total timosaponins has the restrain effect on myocardial hypertrophy induced by isoprenaline in mouse. 结论 黄芪总皂苷对盐酸异丙肾上腺素所致小鼠心肌肥厚具有显著的抑制作用;
- Methods The myocardial hypertrophy model was established by administrating the isoprenaline subcutaneously in mouse. 进行初步药效学试验。
- AIM: To investigate the role of neuropeptide Y (NPY) i n hypertensive myocardial hypertrophy in rats. 目的:研究神经肽Y(NPY)在高血压心肌细胞肥大中的作用。
- Keywords Nicorandil;L-thyroxine;Myocardium hypertrophy;Rats; 尼可地尔;甲状腺素;心肌肥厚;大鼠;
- It is emerging that NHE 1 also contributes to myocardial hypertrophy and heart failure due to chronic maladaptive stimulation. 近期的研究提示钠氢交换泵1也介导长期不良刺激引起的心肌肥大和心衰。
- Conclusion Deficience of OPG induces up-regulation of serum RANKL level and myocardial hypertrophy, but has no effect on serum estrogen level. 结论OPG缺乏导致血清RANKL水平升高,左心室心肌细胞肥大,但不影响血清雌激素水平。
- CONCLUSION:MAPK system may be i nvol ved in the pathophysiology of hypertensive myocardial hypertrophy induced by NPY . 结论:MAPK系统可能在NPY致心肌细胞肥大的信息传导途径中发挥重要的作用。
- It also revealed the antagonistic effect on myocardial hypertrophy pronouncedly in total timosaponins and total astragalus saponins treated group. 知母总皂苷与黄芪总皂苷组成的复方均可延长小鼠的跑步时间、游泳时间和缺氧存活时间,可显著降低模型小鼠心指数。
- Objective To study the effects of Shengmai injection solution on myocardial hypertrophy and calcium overload induced by hypertension in rats. 摘要目的研究生脉注射液对慢性压力过负荷引起肌浆网钙泵功能紊乱的防治作用。
- CONCLUSIONS:Benazepril inhibited ERK activation,resulting in regression of myocardial hypertrophy and accompanied by the reduction of BNP level. 结论:苯那普利能通过抑制ERK活性逆转心肌肥厚,伴随BNP水平下降;
- Objective:To investigate the differences in developing mechanism between hypertensive myocardial hypertrophy and exercised myocardial hypertrophy. 目的:探讨高血压性与运动性心肌肥厚的产生机制的差异。
- The relationship between the mRNA expression of LPA receptor subtypes and the myocardial hypertrophy and apoptosis in AMI rat and in AMI rat treated with carvedilol were studied. 提示LPA三种受体亚型在心肌重塑过程中有重要作用,卡维地洛的治疗机制可能与LPA受体信号通路相关。
- We can use DTI to distinguish hypertension with left ventricular hypertrophy in patients and physiologic myocardial hypertrophy in athletes and to assess the function of left ventricle. DTI技术可实时、准确地反映心肌舒缩功能状况,并可依此对生理性肥厚心肌和高血压左心室肥厚进行鉴别。
- Some inflammatory cytokines may contribute to the development and progression of heart failure by promoting myocardial hypertrophy,provoking contractile dysfunction,and inducing apoptosis. 一些炎症因子能通过促进心肌细胞肥厚、恶化心肌收缩功能以及诱导凋亡,在心衰的发展过程中具有重要作用。
- Conclusion Shengmai injection solution could not only prevent and treat myocardial hypertrophy, but also could maintain the functions of SERCA and prevent myocardial calcium overload. 结论生脉注射液不仅能防治心肌肥厚,而且能保护肌浆网钙泵功能,防止心肌钙超载损伤。
- At present,much attention has been paid to various primary and secondary coronary artery diseases in pediatrics as well as coronary artery dysfunction due to myocardial hypertrophy. 目前儿童各类原发或继发性冠状动脉病变、心肌肥厚所导致的冠状动脉功能的改变已逐步引起广泛的关注。
- Effect of calcium activators on signaling transduction of myocardium hypertrophy in cardiac myocytes in vitro 钙激动剂对心肌肥大有关信号转导的作用
- Calcium activator induced the expression of myocardium hypertrophy transcription factor 钙激动剂诱导心肌肥大转录因子的表达