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- OBJECTIVE To study the absorption of Metformin hydrochloride. 摘要目的比较两种盐酸二甲双胍制剂在人体内的吸收。
- Metformin hydrochloride is a type of antidiabetic medicine known as abiguanide. 盐酸二甲双胍是一种降血糖类药物。
- Metformin hydrochloride is an orally administered biguanide widely used in clinical medicine. 盐酸二甲双胍是目前广泛用于临床医学的双胍类降糖药。
- OBJECTIVE:To investigate the dissolubility of commercial metformin hydrochloride tablets from different manufactories. 目的:考察市售不同厂家盐酸二甲双胍片的溶出度。
- HPLC was used in the determination of Dicyandia mide in Metformin hydrochloride. 采用高效液相色谱法控制二甲双胍中双氰胺杂质的限量。
- Objective To study the preparation and stability of metformin hydrochloride oral solution. 目的研究盐酸二甲双胍口服溶液剂的制备工艺及稳定性。
- Sustained-release Tablets is prepared using metformin hydrochloride as model drug,soluble HPMC and insoluble ethylcellulose as sustained material. 以盐酸二甲双胍为模型药物,以羟丙甲基纤维素及乙基纤维素为缓释骨架材料,制备相对刚性骨架缓释片。
- RESULTS The concentrations were incomplete for enteric-coated Metformin Hydrochloride tablets after the same doses were administrated. 结果在测定方法与给药量相同的情况下,肠溶片的血药浓度数据不完整。
- OBJECTIVE To compare the dissolubility and the other parameters between imported and domestic metformin hydrochloride tablets. 目的考察市售进口和国产两种盐酸二甲双胍的溶出度及其他体外指标。
- Compared with metformin hydrochloride, an already widely used chemical medicine, fibroin revealed obvious effect on lowering blood-glucose. 与已经开发利用的化学降血糖药剂盐酸二甲双胍片相比，丝素降血糖的效果也比较明显。
- Objective:To study the effects of different coating technique in the preparation of metformin hydrochloride(MH) sustained-release tablets. 目的:研究3种不同包衣技术对盐酸二甲双胍缓释片体外释药的影响。
- Objective Survey the curative effect of Desogestrel and Ethinylestradio Tablets combined with Metformin Hydrochloride Tables for PCOS. 目的观察妈富隆联合二甲双胍治疗多囊卵巢综合征(PCOS)的疗效。
- HPLC method for the determination of glibenclamide and its content uniformity in compound metformin hydrochloride tablets was presented. 建立了测定复方盐酸二甲双胍片中格列本脲含量及其均匀度的HPLC法。
- The differences show that Yitemin may contain Glibenclamide, and has little possibility of containing Gliclazide Tablets and Metformin Hydrochloride Capsules. 综合分析研究后知在胰特敏中可能含有格列本脲。
- The methods used to detect metformin hydrochloride both in drug and human plasma were summarized in this review.The promising development was also outlined. 本文综述了目前分析测定药剂中和血液中盐酸二甲双胍的各种方法,并对今后的发展提出了展望。
- Using the JR Spectrum method analyzes the spectrum of Yitemin, by using the same way studies the blood sugar medicine: Glibenclamide, Gliclazide Tablets and Metformin Hydrochloride Capsules. 摘要运用傅立叶红外光谱对（胰特敏）和其它几种西药降糖药物进行了指纹图谱分析研究。
- The results showed that phamarcokinetic characteristics was very similar between Metformin Hydrochloride Sustained-release Tablets and GLUCOPHAGE XR.Two formulations were bioequivalent. 羟丙甲基纤维素、乙基纤维素、乳糖用量是影响缓释效果的主要因素。
- Methods Ion-exchange resin-drug metformin hydrochloride complexes were prepared as core materials, and followed by coating using ethylcellulose (EC) by the emulsion solvent diffusion technique. 方法以自制的离子交换树脂-药物复合物作为核心材料,乙基纤维素(EC)做为包衣材料,用乳化溶剂扩散法制备了盐酸二甲双胍的缓释微囊。
- METHODS:The in vitro dissolubility of 14 kinds of commercial metformin hydrochloride tablets was determined by basket method and the dissolution parameters were analyzed with variance analysis method. 方法:采用转篮法对14个厂家的盐酸二甲双胍片进行体外溶出度测定,并进行溶出参数方差分析。
- The results show that there are some similarities between Yitemin and Glibenclamide, and that there are also great differences between Gliclazide Tablets and Metformin Hydrochloride Capsules. 发现胰特敏和格列本脲红外光谱图有较大的相似性，但是胰特敏和格列齐特、盐酸二甲双胍的指纹图谱有很大的差异存在。
