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- OBJECTIVE To investigate the effect of Shengmai injection (SMI) on the drug metabolizing enzyme of liver in mice. 目的:观察生脉注射液(SMI)对小鼠肝药酶的影响。
- Genetic polymorphisms of drug metabolizing enzymes. 药物代谢酶类基因多态性研究。
- Some applications of phenotyping &genotyping of drug metabolizing enzymes are also introduced. 最后主要讨论了表型分型和基因分型在药物代谢酶研究中的一些应用。
- Objective: To review the effects of the active components of Chinese herbs on drug metabolizing enzymes. 目的:综述近年来中药有效成分对药物代谢酶的影响的研究进展。
- The team detected the effect by examining the metabolic enzyme aconitase, which is susceptible to damage from ROS. 小组监测代谢酶顺乌头酸酶以检测这种效应，这种酶是可以被活性氧的损伤作用影响的。
- Malate dehydrogenase (MDH) is an essential metabolic enzyme, which has high economic value in protein research. 苹果酸脱氢酶不仅是一种重要的糖代谢酶，而且具有较高的经济价值和理论研究价值。
- With the exception of drug metabolizing enzymes, drug receptors are another important kinds of proteins involved in drug response. 这些差异的产生是遗传因素与环境因素共同作用的结果，其中遗传因素为决定性因素。
- The activities of metabolizing enzymes were measured by spectrophotography, and hepatic function was determined by biochemical analyser. 结果彗星发生率染毒组显著高于对照组,肝细胞和血淋巴细胞彗星发生率显著相关。
- Acting on entero-transport protein and intestinal mucosa metabolic enzyme,grapefruit juice can change the bioavailability of many oral drugs. 葡萄柚汁通过对肠道转运蛋白及肠黏膜上皮细胞上代谢酶的影响从而改变很多口服药物的生物利用度。
- Aim: To detect effect of the different frequency of chronic electrical stimulation(CES) on myofibrillar isoform,myosin heavy chain(MHC) and metabolic enzyme activities. 目的:探讨不同频率慢性电刺激对膈肌肌纤维亚型、肌球蛋白重链(MHC)亚型和代谢酶活性的适应性变化的影响。
- The laying hens were fed with diets containing selenium and iron at high level and the changes of metabolic enzyme activities in plasma and liver homogenate were studied. 用高硒高铁日粮饲喂产蛋母鸡,观察血浆及肝匀浆代谢酶活性的变化。
- To investigate DNA damage of liver cells and lymphocytes of rats exposed to vinyl chloride (VC),to examine the activities of VC metabolizing enzymes including GST,CYP2E1,ADH,and ALDH, and to explore early sensitive indexes to detect damage induced by VC. [目的 ]研究氯乙烯 (VC)对大鼠肝细胞和外周血淋巴细胞DNA的损伤作用 ,及对VC代谢酶 [谷胱甘肽硫转移酶 (GST)、细胞色素P45 0 2E1(CYP2E1)、乙醇脱氢酶 (ADH)和乙醛脱氢酶 (ALDH) ]活性的影响 ; 探索VC所致损伤的早期敏感检测指标。
- This review is focused on two main types of markers of susceptibility to benzene-induced hematotoxicology, metabolizing enzymes, DNA repairing enzymes, their polymorphisms are also addressed. 介绍苯致血液毒性两大类主要的易感性标记物、代谢酶,DNA修复酶及其多态性;
- Methods:By immunohistochemical methods, we examined the expression pattern of major arachidonic acid metabolizing enzymes in 17 samples of Crohn;s disease with associated intestinal fistula. 方法:通过免疫组化考察花生四烯酸代谢的主要酶系在17例克罗恩病并发肠瘘的病变肠组织的表达情况。
- The paper simply reviews data from recent studies in EGCG inducing cell apoptosis,arresting cell cycle,restraining cell proliferation,regulating metabolize enzyme and inducing cell differentiation. 该文就EGCG诱导细胞凋亡、阻滞细胞周期、抑制细胞增殖、调控致癌物代谢酶类、诱导细胞分化、抑制肿瘤细胞的侵袭和转移、增强机体免疫功能方面研究的一些新进展作一综述。
- Ethanol is maily metabolized in liver by ethanol dehydrogenase,cytochrome P450-2E1 and acetaldehyde dehydrogenase.Ethanol metabolic enzyme plays an important role in the metabolism of ethanol. 乙醇在肝内主要由乙醇脱氢酶、细胞色素P450-2E1和乙醛脱氢酶代谢,乙醇代谢酶在乙醇代谢过程中发挥着最重要的作用。
- Emergence of cancer relates not only to activation of oncogene, inactivation of anti-oncogene and metabolic enzyme gene, but also to DNA repair gene which plays an important role in stability of DNA. 摘要癌症的发生不但与癌基因激活、抑癌基因失活、代谢酶基因异常有关，与修复酶基因可能也有关系，因而也日益受到关注。
- Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) methods were used to measure DNA damage repair gene XPC and folate metabolism enzyme gene MTHFR polymorphisms. 对照组选自同期居住在扬中境内的居民，与病例按性别和年龄组进行成组频数匹配，要求身体健康，无恶性肿瘤及胃和十二指肠溃疡病史，征得同意后采集静脉血并进行流行病学问卷调查。
- Effects of Cd on brain AChE and metabolic enzymes in tissues of T. Nilotics. 镉对罗非鱼脑AChE及组织中代谢酶的影响。
- Objective: To promote the study of drug metabolic enzymes in clinical practice. 目的:为了促进药物代谢酶在临床上的深入研究。
