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- marker gene deletion 标记基因删除
- Objective To detect dystrophin gene deletion of Duchenne muscular dystrophy (DMD) and make DMD gene diagnosis. 目的探讨Duchenne型肌营养不良症（DMD）患者基因缺失的突变特点并进行基因诊断。
- Abstract:Selective marker gene is usually used to select transformed cells or tissue during gene transfer. 在基因转移过程中，人们常常使用标记基因来筛选转化细胞或组织。
- Results: all of 12 CML cases were bcr/abl gene positive by FISH and 2 cases were associated with ASS gene deletion. 结果:12例CML均检出bcr/abl基因的存在,其中2例伴ASS基因缺失。
- MSP2 is suitable to be used as a marker gene for the genotyping of P.falciparum infection. 海南省不同等位基因型虫株混合感染及多重感染现象比云南省严重。
- As compared with the FBA, the performance of EFM analysis was superior to FBA in prediction of gene deletion phenotype. 通过EFM预测了基因突变后的酵母细胞生长现象,模拟预测结果和实验结果很好吻合;
- The biosafety of marker genes has becoming a common concern. 标记基因的生物安全性成为人们普遍关注的问题之一。
- Methods 38 BPH and 18 normal prostatic tissue were detected for MTS1 gene deletion and mutation by means of PCR-SSCP. 方法用PCR-银染SSCP技术检测18例正常前列腺和38例BPH中抑癌基因MTS1各外显子的纯合性缺失和突变。
- He was also informed that, due to thalassemia gene deletion or mutation is caused by, but not its genetic transmission. 同时他还得知，地中海贫血由于是基因缺失或突变引起的，因此它遗传但不传染。
- Hitchhiking effects also play a role in experiments with marker genes. 附加效应在以标记基因作试验中也是起作用的。
- The hematopoiesis reconstitution was observed and the marker gene in spleen and BM cells of recipients after hematopoiesis reconstitution was examined. 观察受体小鼠造血的重建， 并对造血重建后受体鼠的脾及骨髓细胞进行标志基因的检测。
- GSTM1 gene deletion might bea risk fac tor for endometriosis in women of Han nationality who are native residents in Gu angdong Province. GSTM1基因缺失可能是广东汉族妇女内异症发病的危险性因素之一。
- A new strategy that offers a approach for the elimination of those disadvantages caused by the selectable marker gene is developed. 为了消除这些弊端，一种全新的发展策略即获取无选择标记的转基因植物应运而生。
- Consequently the desirable gene may be linked to a marker gene, e.g. a gene conferring resistance to an antibiotic in the growth medium. 如决定一种是否对培养基上抗菌素产生抗性的性状基因，就可作为标记基因用来判断外源基因是否转入。
- Microinjection experimentation proved that both expression rate of marker gene and the survival rate of transgenic embryos are high. 显微注射实验证实：在青鳉受精卵的单细胞期进行显微注射，标记基因的表达率和胚胎的存活率均较高。
- Schmidt EE, Ichimura K, Messerle KR, et al. CDKN2(P16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas [J ]. Cancer Res,1994,54(24): 6321. 徐庆中;卢德宏.;脑肿瘤病理分类和诊断工作中的新问题[J]
- The detection results of stereo-fluorescence microscope show that green-fluorescent protein (GFP) gene is a kind of ideal marker gene. 立体荧光显微镜检测结果表明：绿色荧光蛋白（GFP）基因是一种理想的标记基因。
- Conclusions: PI3K gene deletion or pharmacologic inhibition of PI3K leads to perturbations of critical innate immune responses of the lung to challenge with S. pneumoniae. 结论I3K基因缺失以及药物抑制PI3K干扰了在肺脏抵抗肺炎球菌时具有关键作用的先天免疫反应。
- Each open reading frame (ORF) is knocked out using a PCR-based gene deletion strategy that takes advantage of the high degree of homologous recombination in yeast. 每个开放读码框使用基于PCR基因删除策略,使用在酵母中的高度同源重组优势。
- Here were discussed the safety of marker genes and their elimination from the transgenic plants. 本文主要讨论标记基因的安全性及标记基因消除的方法等问题。
