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- Keywords nuclear magnetic resonance;structure elucidation;lomerizine dihydrochloride;ultraviolet spectrum;infrared spectrum;mass spectrum; 核磁共振谱;结构确证;盐酸洛美利嗪;紫外光谱;红外光谱;质谱;
- lomerizine dihydrochloride 盐酸洛美利嗪
- The resultant hydrolytic reaction product is dihydrochloride. 所形成的水解反应物是二盐酸。
- METHODS: Lomerizine was determined by LC-ESI-MS selection ion measurement. 方法LC-ESI-MS选择性离子监测方法测定人血浆中盐酸洛美利嗪浓度。
- As a negative control, CsA and lomerizine have no effect on accumulation of Rhodamine123 in HUVECs. 人脐静脉内皮细胞内荧光强度则不受环孢素A和洛美利嗪的影响。
- Second grade national new medicine Lomerizine Hydrochloride has acquired national approval in 2006. 国家二类新药盐酸洛美利嗪2006年获国家批准文号。
- RESULT:Cellular fluorescence of Rh123 in RBMECs increased significantly after incubation with CsA and lomerizine. 结果:环孢素A和洛美利嗪与大鼠脑微血管内皮细胞孵育后能明显提高胞内罗丹明123的荧光强度。
- The resultant hydrolytic reaction product is methylenedioxyamine dihydrochloride. 所形成的水解反应物是二盐酸甲撑二氧胺。
- OBJECTIVE To synthesize Lomerizine hydrochloride,a new drug for the treatment of antimigraine. 目的合成抗偏头痛药盐酸洛美利嗪。
- Levocetirizine Dihydrochloride was prepared from benzoyl chloride by acidylation,hydrogenation,cyclization with an overall yield of 8.05%. 以苯甲酰氯为原料;经酰化;还原;环合等反应合成左旋西替利嗪盐酸盐;反应总收率为8.;05%25。
- Objective:To establish the method for the preparation and quality control of Lomerizine hydrochloride capsules. 目的:建立盐酸洛美利嗪胶囊的制备和质量控制方法。
- The results indicate that arte- sunate is significantly superior to quinine dihydrochloride in both aspects. 结果表明,青蒿琥酯的杀虫速度比二盐酸奎宁快,治愈效果优于二盐酸奎宁。
- The interaction of hematoporphyrin dihydrochloride(HD) with DNA was studied by using neutral red(NR) as a probe. 以中性红(NR)作探针研究了血卟啉(HD)与DNA的相互作用。
- Methods The nitrite was detected from samples by N-Naphthylethylenediamine Dihydrochloride. 方法用盐酸萘乙二胺法检测样品中的亚硝酸盐。
- The currently approved drug in the US, melarsomine dihydrochloride, is marketed under the brand name Immiticide. 目前已经获批的药物有砒霜。
- AIM:To study the effect of lomerizine on the activity of P-glycorprotein(P-gp) in primary cultured rat brain microvessel endothelial cells. 目的:研究洛美利嗪对大鼠脑微血管内皮细胞上P糖蛋白功能的影响。
- Study on Interaction between Hematoporphyrin Dihydrochloride and Herring Sperm DNA by Spectroscopy[J]. 引用该论文 Li Hongbo;Ta Honggui;Wang Xingming;Wang Suqin;Ding Lisheng.
- Aim To investigate the reversal of resistance to doxorubicin by CJZ3,a lomerizine derivative,in doxorubicin-resistant human myelogenous leukemia(K562/DOX)cells. 目的研究洛美利嗪衍生物CJZ3对K562/DOX细胞阿霉素耐药的逆转作用。
- The trade group said the case highlighted an ongoing area of uncertainty that contributed to the status of pyridoxamine dihydrochloride being altered. 而对于商业人士而言,这一事件对盐酸吡哆胺的使用范围造成了不确定。
- Methods:Cetirizine dihydrochloride were synthesized from piperazine hexahydrate and4-chlorobenzyl chloride by six steps reactions. 方法 :对关键的缩合反应进行了改进 ,以六水哌嗪和对氯氯苄为原料 ,经六步反应得到产品。