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- liver stellate cell 肝星形细胞
- Keywords Amydae Carapax extract;liver fibrosis;lipid perioxidation;liver stellate cells;cell factor;extracellular matrix; 鳖甲;肝纤维化;脂质过氧化;肝星状细胞;细胞因子;细胞外基质;
- XBR can prevent the occurrence and development of hepatic fibrosis in rats,the effect may be related to its preventing liver cell against injury,inhibiting the synthesis of extracellular matrix(ECM) and the activation of hepatic stellate cell(HSC). 消瘢方能有效预防肝纤维化的发生、发展,其作用可能与保护肝细胞,抑制细胞外基质合成及HSC活化有关。
- International Hepatology: Besides the important role of hepatic stellate cell in liver fibrosis development, are there any other important mechanisms involving liver fibrosis development? 国际肝病:除了肝星状细胞在肝纤维化发生中的重要作用,还有哪些机制参与了肝纤维化的发生?
- Hepatic stellate cells activated and proliferated. 贮脂细胞活化、增殖。
- In mice lacking key senescence regulators, stellate cells continue to proliferate, leading to excessive liver fibrosis. 缺乏关键衰老调节因子的老鼠,星形细胞持续增生将导致肝脏过度纤维化。
- sarcoma of stellate cell of liver' 肝星形细胞肉瘤
- Activation of hepatic stellate cell (HSC) has become the cellular basis for hepaticfibrogenesis. 肝星状细胞(HSC)的活化是肝纤维化发生、发展的细胞学基础。
- Objective:To study the effects of bupleurum on collagen degradation of hepatic stellate cell in vitro. 目的:观察柴胡对肝星形细胞有关胶原降解基因表达的影响。
- AIM: To activate hepatic stellate cells (HSC) in vitro in precision-cut liver slices (PCLS) stimulated by acetaldehyde for studying and screening anti-fibrotic drugs. 目的:在精密肝切片中利用乙醛激活肝星状细胞,建立一种星状细胞激活的体外模型,为研究和筛选阻抑肝纤维化发生的药物奠定基础。
- Aim The effect of compound 861(Cpd 861) on rat hepatic stellate cell(HSC) proliferation and collagen synthesis in vitro was observed. 目的观察中药复方861对体外培养肝星状细胞增殖及胶原合成的影响。
- Conclusion: Inhibition of hepatic stellate cell proliferation and collagen synthesi s may be one important mechanism of hepatoprotective and antifibrotic properties of silibinin. 结论:抑制贮脂细胞增殖和胶原合成可能是水飞蓟宾保护肝脏抗硬化机制之一。
- HC may induce fibrogenesis directly by hepatic stellate cell actiation or indirectly by promoting oxidatie stress and apoptosis of infected cells. 慢性丙型肝炎可能通过肝脏星形胶质细胞的活化、或者间接通过促进氧化应激和受感染细胞的凋亡,直接诱导纤维形成。
- Recently, a lot of data indicate hepatic stellate cells (HSC) is the key cell of formation of ECM and HSC is also the core link of occurrenc of hepatic fibrosis. 现已证实,肝星形细胞(hepatic stellate cell,HSC)是肝脏产生 ECM 的主要细胞,HSC 活化是肝纤维化发生的中心环节。
- Microscopically, it consists of stellate cells in loose myxoid stroma. A few entrapped tubules may be present. 显微镜下可见肿瘤内含有星状细胞,散落在疏松的黏液间质内。可有少量内陷的小管。
- Mesenchyme -- embryonic c.t. with multipotential cells.The stellate cells are beginning to form fibers. 间充质---胚胎时期结缔组织,含有多种分化潜能的细胞这种星形细胞可合成纤维。
- An effective method of isolating and culturing human hepatic stellate cells ZHANG Wen-wei, XU Lie-ming. 分离和提纯;细胞培养,方法;人肝星状细胞
- We know that hepatic stellate cells are still the major source of extracellular matrix during fibrogenesis. 我们知道肝星状细胞还是纤维化过程中细胞外基质的主要来源。
- It is well known that the activation of hepatic stellate cells (HSCs) is the key event in the process of hepatic fibrosis. 肝星状细胞(hepatic stellate cells,HSCs)的活化被认为是这一过程中的关键事件。
- After using drugs,the hepatic mitochondrion and rough EM proliferated;hepatic stellate cells and collagenous fibers reduced obviously. 应用药物防治后,肝细胞线粒体、粗面内质网增生,贮脂细胞和胶原纤维数量明显减少。
