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- iodophenol methyltransferase 碘酚甲基转移酶
- Some of this damage can be repaired by the DNA methyltransferase MGMT. 这类损伤中有一部分可被DNA甲基转移酶MGMT所修复。
- In vitro activity assays confirmed that recombinant OsSET3 was a functional H3K9 methyltransferase while OsSET2 and OsSET4 were not. 利用大肠杆菌表达的OsSET2、OsSET3和OsSET4重组蛋白进行的体外活性检测实验证明OsSET3具有组蛋白H3K9的甲基转移酶活性,而OsSET2和OsSET4不具有该活性。
- The massive researches on histone methyltransferase and effector proteins in recent years have increased our understanding of H3K4 methylation. 随着对组蛋白甲基化转移酶及相关作用蛋白研究的深入,人们对组蛋白H3第4赖氨酸的甲基化的功能也有了更深的了解。
- Objective To explore the role of protein expression of DNA methyltransferase 1(DNMT1) in lung adenocarcinoma carcinogenesis and prognosis. 目的检测肺腺癌中DNA甲基转移酶1(DNMT1)蛋白水平的表达,探讨其在肺腺癌发生中的作用及其预后价值。
- They found that HP1 proteins, which bind to methylated histones, also interact with the DNA methyltransferase, DNMT1, to stimulate its DNA methylation actiity. 他们还发现与甲基化组蛋白相结合的Hp1蛋白和DNA甲基转移酶(DNMT)即DNMT1之间也存在相互作用,它可激发DNA甲基化活性。
- Objective:To detect the expression of O6-methylguanine-DNA methyltransferase (MGMT),and it s effect of promoter hypermethylation on tumorigenesis and progression. 目的:检测大肠癌组织中O6-甲基鸟嘌呤-DNA甲基转移酶(MGMT)的表达情况及其在肿瘤发生发展中的作用和临床意义。
- Comparing to Candida albicans and Sacchromyces cerivisiae sterol methyltransferase,A. fumigatus Erg6p had 57% and 50% identity, and had 70% and 63% similarity in amino acid sequences,respectively. 其编码的蛋白与白念珠菌、酿酒酵母固醇甲基转移酶(Ers6p)的氨基酸相同率分别为57%25和50%25,相似率分别为70%25和63%25。
- DNA methyltransferase inhibitor 5-Aza-CdR can induce demethylation in the promoter region of RASSF1A. It can also reverse epigenetic transcriptional silencing caused by methylation and induce the re-expression of RASSF1A in QBC-939. DNA甲基转移酶抑制剂5-Aza-CdR能够诱导RASSF1A基因启动子区域去甲基化,并通过该机制诱导RASSF1A基因在人胆管癌细胞系QBC-939中的表达。
- Thiopurine methyltransferase (TPMT) plays an important role in the metabolism of 6-MP.This article reviews the literature on the role of TPMT measurement prior to treatment of IBD with AZA/6-MP. 硫嘌呤甲基转移酶(TPMT)是6-MP代谢的关键酶,本文综述IBD患者用AZA/6-MP治疗前检测TPMT的临床意义。
- Thiopurine methyltransferase(TPMT) plays an important role in the metabolism of 6-MP.This article reviews the literature on the role of TPMT measurement prior to treatment of IBD with AZA/6-MP. 硫嘌呤甲基转移酶(TPMT)是6-MP代谢的关键酶,本文综述IBD患者用AZA/6-MP治疗前检测TPMT的临床意义。
- To test whether DNA methylation plays a role in somaclonal variation, the calli were treated with 5-azacytidine that reduces cytosine methylation by blocking activity of DNA methyltransferase. 为了检测DNA甲基化在体细胞克隆多样性中的作用,愈伤组织用5-氮胞苷进行处理,5-氮胞苷通过抑制DNA甲基转移酶的活性降低胞嘧啶的甲基化水平。
- O6-Methylguanine-DNA methyltransferase(MGMT)is an important DNA repair gene in human cells.It plays an important role in resisting cellular DNA damage induced by alkylating agents. O6甲基鸟嘌呤DNA甲基转移酶(MGMT)是细胞中一种重要的DNA损伤修复酶,它在抵御烷化剂所致的细胞突变和死亡中起重要作用。
- Modulation of O6-methylguanine-DNA methyltransferase(MGMT) and mismatch repair(MMR) expression in tumors and normal tissue is currently being investigated as a possible strategy ... 靶向DNA修复机制增强抗肿瘤化疗药物的疗效、克服肿瘤耐药正成为肿瘤个体化化疗研究的一个重要领域。
- ribosomal protein L11 methyltransferase 钩端螺旋体甲基化转移酶
- betaine homocysteine methyltransferase 甜菜碱同型半胱氨酸甲基转移酶
- Tetrahydrofolate methyltransferase deficiency 四氢叶酸甲基转移酶缺乏
- tetrahydropteroylglutamate methyltransferase 四氢蝶啶谷氨酸甲基转移酶
- Tetrahydropteroyltriglutamate methyltransferase 四氢碟酰三谷氨酸甲基转移酶
- thetinThetin-homocysteine methyltransferase 噻亭高胱氨酸甲基转移酶