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- Effect of Mechanical Pressure on Cytoskeletal Structure in Rabbit Mandibular Condylar Chondrocytes and the Function of Intracellular Calcium Release Channel Block in it. 机械压力及细胞内钙释放通道阻滞对髁突软骨细胞骨架影响的研究。
- Keywords ultra low molecular weight heparin;glutamate;calcium overload;intracellular calcium release;neuroprotection;neurotoxicity; 超低分子量肝素;谷氨酸;钙超载;神经细胞内钙释放;神经保护作用;神经毒;
- intracellular calcium release 内钙释放
- The inhibitory effect of the extract from SGY on contractility of isolated rat colonic smooth muscle strips may be associated with blocking VDC,ROC and SOC to prevent the calcium influx as well as to prevent the release of intracellular calcium. 疏肝饮具有抑制大鼠结肠平滑肌收缩的作用,机制可能涉及通过阻断电压门控钙通道(VDC)、受体操纵性钙通道(ROC)和钙库调控性钙通道(SOC)抑制胞外Ca2+内流,同时涉及抑制胞内Ca2+的释放。
- At 24h after reperfusion the intracellular calcium level reached the peak, and began to decease at 72h. 钙离子于再灌注后1h开始升高,至24h达到高峰,72h出现下降。
- Conclusion: In normoxia and hypoxia,DHC decreases the increased [Ca 2+ ] i. It can prevent intracellular calcium overload. DHC对低氧后心肌 [Ca2 + ] i 增加明显减缓。
- Oral L arginine could inhibit platelet intracellular calcium oscillations induced by ADP through promoting NO and cGMP synthesis. 口服精氨酸可以通过激活血小板的左旋精氨酸 /一氧化氮通路 ,促进一氧化氮和环磷酸鸟苷的合成使二磷酸腺苷诱导的血小板钙波动峰值降低。
- PDGF could increase osteoblastic surface granules, reticular fibers and intracellular calcium salt crystals, and calcium granule mitochondria. (2)PDGF促使细胞内线粒体更丰富，粗面内质网增多。
- Purpose To observe real-time changes of intracellular calcium arose from glutamate and taurine in cultured rat hippocampal neurons. 目的观察抑制性氨基酸牛磺酸对兴奋性氨基酸谷氨酸所致胞内钙超载的影响。
- INHIBITION OF SNP ON 5-HT INDUCED INTRACELLULARFREE CALCIUM CONCENTRATION RISE AND CALCIUM RELEASE FROM CALCIUM STORE? SNP抑制5-HT诱导的胞内游离钙浓度升高和内钙释放
- Objectives: Endoplasmic reticulum (ER) extensively exists in eukaryocytes, which is a locus where proteins are synthesized, modified, folded and intracellular calcium is saved. 目的:内质网(endoplasmic reticulum, ER)广泛存在于真核细胞中,是蛋白质合成、折叠和运输以及细胞内钙离子储存的主要场所。
- Nishio M,Wasserstrom JA. Ouabain increases sarcoplasmic reticulum calcium release in cardiac myocytes[J]. J Pharmacol Exp Ther，2004, 308(3):1181. 韩玲，陈可冀.;黄芪对心血管系统作用的实验药理学研究进展[J]
- Involvement of P2Y receptor in pain modulation may be related to the capsaicin receptor (VR1) and the enhancement of intracellular calcium concentration. P2Y受体调制伤害性感受的机制可能和增加细胞内钙离子浓度有关;也可能和VR1有关.
- The Calcium pump takes an important part in intracellular calcium homeostasis.It's well know that calcium is concerned with muscle contraction, nerve conduction and emiocytosis. 钙泵对维持细胞内钙离子的平衡起主要作用,而钙离子同时与肌肉收缩、神经传导、细胞分泌有关。
- Free fatty acid stimulating increase of intracellular calcium and activation of PKC inducing apoptosis is one of pathogenetic mechanisms of hyperlipaemic pancreatitis. 游离亚油酸刺激腺泡细胞内钙升高和活化PKC诱导细胞凋亡可能是高脂血症性胰腺炎的发病机制之一。
- Ryanodine receptor (RyR), a calcium release channel within the sarcoplasmic reticulum (SR) membrane, is a key protein in skeletal and cardiac excitation-contraction coupling. Ryanodine受体(ryanodine receptor, RyR)是位于细胞内肌质网(sarcoplasmic reticulum, SR)膜上的钙释放通道，是骨骼肌和心肌细胞兴奋-收缩偶联过程中的关键蛋白。
- AIM To investigate the inhibitory actions of ethyl ferulate on platelet congregate induced by ADP, and the effect of platelet intracellular calcium oscillations. 目的 观察阿魏酸乙酯抗二磷酸腺苷 (ADP)诱导的血小板聚集作用 ;及其对血小板细胞内钙波动的影响 .
- These data are consistent with the hypothesis that calcium release from the granules may increase the cytoplasmic calcium concentration, which again triggers off the granule exocytosis. 该结果支持颗粒内钙释放入胞质,参与胞质内游离钙浓度的升高,进而激发颗粒胞吐的假设,为证实嗜铬颗粒是一种细胞内钙库并参与细胞分泌提供了实验依据。
- Neurochemistry,flow cytometer,fluorescence labeling technique and Western blotting were adopted to detect activities of Na+ K+ ATPase and Ca2+ ATPase, levels of intracellular calcium and free calmodulin (CaM),and the total CaM expression. 采用神经生化、流式细胞仪、荧光标记术及Westernblotting等方法,定量观测了实验大鼠海马Na+-K+-ATP酶与Ca2+-ATP酶活性,细胞内游离钙离子含量与钙调素(CaM)相对活性平均通道荧光,以及海马组织总CaM表达的动态变化规律。
- Vestibular ganglion cells were isolated with pipetting after enzymatic treatment for 30 min and loaded with calcium sensitive dye fura-2. Morphology of the VGC and intracellular calcium changes were monitored with digital imaging microscopy. 经酶消化后用机械法分离成单细胞,用钙离子敏感的荧光染料Fura-2染色,于数字荧光显微镜下观察。
