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- The main obejective is to construct an efficiently expressive prokaryotic clone of the second immunodominant epitopes in HTV-1 gp41, detect its products and evaluate it in testing the anti-HTV-1 antibody. 本课题构建了HIV-1 SF2株跨膜蛋白gp41第二优势表位簇基因的原核高效表达克隆，初步检验该融合蛋白抗原性，探讨将其作为侯选多肽用于制备诊断试剂、检测HIV-1抗体的可能性； 并探讨提高原核表达的途径。
- Keywords Plasmodium falciparum;Malaria vaccine;Monoclonal antibody;Immunodominant epitopes; 恶性疟原虫;疟疾疫苗;单克隆抗体;免疫显性表位;
- Expression of chimeric antigen of HCV with multiple immunodominant epitopes in E. Coli and its application for serological tests 丙型肝炎病毒优势表位嵌合抗原在大肠杆菌中的表达及其在血清学检测中的应用
- immunodominant epitopes 免疫显性表位
- Identification of a Common Immunodominant Epitope of Coxsackie B Virus Coat Protein VP1 With Synthetic Peptides 应用合成肽研究柯萨奇B病毒衣壳蛋白VP1的共同抗原表位
- Keywords HIV envelope protein GP41;gene expression;immunodominant epitope;viral envelope proteins; HIV包膜蛋白质GP41;基因表达;免疫优势表位;病毒融合蛋白质类;
- Background: Epitopes are the sites to which antibodies bind. 背景： 表位是绑定抗体的位点。
- immunodominant epitope 优势免疫表位
- In conclusion, B-cell epitopes of SARS corresponded to novel coronavirus. 总而言之，严重急性呼吸道症候群的B细胞抗原决定位序列符合此新的冠状病毒。
- Partial Protection Induced by Phage Library-selected Peptides Mimicking Epitopes of Schistosomiasis Japonicum. 从随机多肽库中筛选日本血吸虫抗原模拟表位诱导保护性免疫的研究。
- E2 protein, including hypervariable region 1 (HVR1) in the N-terminal region, contains some epitopes that can induce neutralizing antibodies. 包括高变区的E2蛋白含有中和性抗原表位，能诱导机体产生中和性抗体。
- Conclusion: The DQA1 and DQB1 epitopes identified here seem to be immunogenic and to elicit DQ antibodies. 结论：此处的DQA1和DQB1表位似乎能够产生免疫性，且能够诱导产生抗体。
- Objective To characterize the intertype epitopes on human adenovirus (HAdV) hexon. 目的 对人类腺病毒 (adenovirus,AdV)六邻体型间抗原位点的特性进行研究。
- Objective To identify HLA-A0201 restricted CD8~+ CTL epitopes in mycobacterium tuberculosis (Mtb) antigen Ag85A. 目的预测及鉴定新的HLA-A*0201结核分枝杆菌(Mycobacterium tuberculosis,Mtb)抗原Ag85A中的CD8+CTL优势表位。
- The epitopes recognized by aPTs have not yet fully defined,which are commonly detected by ELISA methods. 检测方法一般为酶联免疫吸附测定(ELISA)。
- The feature of epitopes is diversity, which has the relation with the clinical symptom, race and local environment. ScL 70的抗原决定簇具有多样性 ,不同抗原决定簇的活性与患者的临床症状以及人种、地域环境有关。 本文就该领域近年的研究进展做一综述。
- The C terminus of NP contains the type-specific B cell epitopes, which occupies C terminus, about half of NP. 上述研究结果提示，体外表达NP蛋白的高变区，有可能用于汉坦病毒的分型检测研究。
- Cultured tet+ B cells produced antibodies specific for epitopes of the tetramer antigen. 培养的四聚物阳性B细胞产生大量针对四聚物抗原的表位抗体。
- Objective To establish an effective method for loc ating T cell epitopes on superantigens. 目的建立一种有效的探找超抗原T细胞识别表位的新方法。
- In addition, interference of antibody and growth factor binding with heparan sulphate epitopes was tested. 另外，检测抗体和绑定硫酸乙酰肝素表位的生长因子的干扰作用。
