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- Here we use renal capsule transplantation in immunodeficient NOD/SCID mice to identify a human colon cancer-initiating cell (CC-IC). 本实验在免疫缺陷的NOD/SCID小鼠身上采用了肾小囊移植的方法,鉴定出一株人类结肠癌起始细胞(CC-IC)。
- Aim:To observe the apoptosis induced by Calamistrin J on human colon carcinoma Lovo cells,and to explore its mechanism. 目的:观察刺果紫玉盘素J(Calamistrin J,Cal-J)诱导人结肠癌Lovo细胞凋亡的作用,并探讨其诱导细胞凋亡的可能机制。
- CLT can induce apoptosis in vitro in human colon cancer cell line CCL 229.The apoptosis inducing effect may be G1 phase specific. 克霉唑对人结肠癌细胞系CCL229有明显的凋亡诱导作用,并且能特异地诱导G1期细胞凋亡。
- ETB-2 could significantly restrain the growth of experimental human colon cancer in BALB/C nude mice and its action was of dose-dependent. ETB-2可显著抑制裸鼠人结肠癌的生长,并有一定的量-效关系;
- Objective: To study the effect of the angiogenesis inhibitor SU6668 combined with 5-Fu on liver metastasis in human colon cancer. 目的:探讨血管生成抑制剂SU6668联合5-Fu对人结肠癌肝转移的抑制作用。
- AIM: To construct a yeast two-hybrid cDNA library of hydroxycamptothecin-resistant human colon cancer cell line SW1116/HCPT in yeast cells. 目的:构建羟基喜树碱耐药结肠癌细胞株SW1116/HCPT细胞的酵母双杂交cDNA文库.
- These trisomic mice where crossed with mice that carry a mutation that causes intestinal tumors, like those seen in human colon cancers. 然后将这些三体小鼠与携带能引起肠道肿瘤的变异基因(与人类结肠癌基因类似)的小鼠进行杂交。
- The study included 18 rats that were gien a compound (azoxymethane) to induce colon cancer in a manner similar to human colon cancer deelopment. 该研究纳入18只大鼠为研究对象,研究人员给这些大鼠注射氧化偶氮甲烷,诱导大鼠产生与人类类似的结肠癌。
- AIM To observe the combination effects of 5-fluorouracil (5-FU) and curcumin in human colon carcinoma cell line HT-29 in vitro. 摘要 目的 体外观察5-氟尿嘧啶与姜黄素联用对人结肠癌HT-29细胞增殖的相互作用。
- The study included 18 rats that were given a compound (azoxymethane) to induce colon cancer in a manner similar to human colon cancer development. 该研究纳入18只大鼠为研究对象,研究人员给这些大鼠注射氧化偶氮甲烷,诱导大鼠产生与人类类似的结肠癌。
- Objective The study investigated the effect of gastrin on tyrosine phosphorylation and protein expression of focal adhesion kinase (FAK) in human colon cancer cells. 目的研究胃泌素对人结肠癌细胞信号分子黏着斑激酶(FAK)酪氨酸磷酸化和蛋白质表达的影响。
- Thi s study was designed to investigate t he relationship between multidrug r esistance in human colon carcinoma LoVo /Adr cell s and the level of cytoplasmic Ca 2+ . 本文的目的是探讨人结肠癌LoVo/Adr细胞耐药性与细胞内Ca2+浓度之间的关系。
- Objective To study the expressions and clinical significance of COX-2 and nm23-h1 in human colon cancer, adenomatous polyps and normal para -cancer colon mucosa. 目的研究结肠癌、结肠腺瘤和癌旁正常结肠黏膜组织中环氧化酶2(COX-2)及nm23-h1的表达及其临床意义。
- MPA has significant inhibitory effect on the growth of human colon cancer cells,which may be related to Fas expression upregulation on cancer cell surface and G_(1) phase arrest. MPA对结肠癌细胞具有显著的抑制作用和诱导凋亡的作用,其机制可能与MPA使结肠癌细胞停滞于G1期及细胞表面Fas表达上调有关。
- Gastrin-gastrin receptor signal transduction pathway can obviously induce u-PA expression in human colon cancer cells via activating the phosphorylation of p38 kinase. 胃泌素与其受体结合后,可通过p38 MAPK信号转导通路诱导结肠癌细胞表达u-PA。
- Results Liver metastasis models of human colon carcinoma (HCA-HMN-1) and human rectal carcinoma (HRA-HMN-2) were established after screening from 34 colorectal carcinomas. 结果从34例人结直肠癌标本中筛选出一株人结肠癌裸鼠肝转移模型HCA-HMN-1,已传至18代;
- In nude mice - animals with an inhibited immune system - engrafted with human colon cancer, the researchers first injected the engineered mesenchymal stem cells, then 5-FC. 在移植有人类结肠癌的裸鼠(没有免疫功能)中,研究人员首先注射遗传工程得到的间充质干细胞,然后注射5-FC。
- The combination of 5-fluorouracil(5FU) with p14ARF gene could increase the inhibitory function of 5FU and sensitize human colon cancer LOVO cell line to 5FU. pl4ARF基因和化疗药物5FU联合用于结肠癌LOVO细胞能够加强5FU的生长抑制作用,明显提高LOVO细胞对5FU的敏感性。
- It's only human nature to want a comfortable life. 想过舒适的生活不过是普通人的本性。
- The apoptotic rate in ETB-2A, ETB-2B and ETB-2C was significantly higher than that in control(P< 0.01). Conclusions ETB-2 could significantly inhibit the growth of experimental human colon cancer in BALB/C nude mice and its action may be dose-dependent. ETB 2A、ETB 2B、ETB 2C组凋亡率分别与对照组相比 ;差异有显著性 (P <0 .;0 1)。
