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- Glucocorticoid effects on the human trabecular meshwork can be used as a model system in which to study glaucomatous damage to the trabecular meshwork. 糖皮质激素对小梁网的作用可作为一个良好模型用于研究青光眼的发病机制。
- Purpose: To determine the effects of adenovirus -delivered exoenzyme C3 transferase (C3) gene expression in normal or dexamethasone (DEX)-treated human trabecular meshwork (HTM) cell culture. 目的:探讨腺病毒载体介导的外酶C3转移酶(exoenzyme C3transferase,C3)表达对体外培养的正常或地塞米松处理的人类小梁细胞的作用。
- Glucocorticoids cause multiple effects on the human trabecular meshwork including changes in extracellular matrix metabolism, organization of the cytoskeleton, and changes in gene ... 糖皮质激素对小梁网的作用是多方面的,它包括细胞外基质、细胞膜、细胞骨架及细胞核的多重变化。
- Characterization of cytoskeleton and cellular adhesions of cultured human trabecular meshwork cells 人眼小梁细胞的体外培养与细胞骨架和细胞连接的研究
- Expression of Heme Oxygenase-1 in Human Trabecular Meshwork Cells in vitro and the Resistance against Oxidant-induced Injury 体外培养人眼小梁细胞血红素氧合酶-1的表达及其抗氧化损伤作用
- Effects of Pressure on Ultrastructure and Fibronectin Synthesis of Cultured Human Trabecular Meshwork Cells by Open Pressure Controlling Culture System 开放式压力控制培养系统对人眼小梁细胞超微结构及纤维连接蛋白合成的影响
- human trabecular meshwork 人小梁网
- human trabecular meshwork cell 人小梁细胞
- human trabecular meshwork cells 小梁细胞
- Corticosteroids also increase the deposition of ECM in the trabecular meshwork leading to decreased outflow facility. 类固醇也能够通过增加细胞外基质的沉积导致房水流畅系数的下降。
- The effect was thought to be mediated via trabecular meshwork glucocorticoid receptors. 这种效应被认为是通过小梁网的糖皮质激素受体介导的。
- The search led to the identification of mutations in a gene that encodes for a trabecular meshwork protein (TIGR). 这项研究,鉴定出编码小梁网蛋白(TIGR)的突变基因。
- Trabecular meshwork,ciliary body,retina and optic nerve will be the targets for glaucoma gene therapy. 青光眼基因治疗的靶目标包括眼前节的小梁网和睫状体、眼后节的视网膜神经节细胞等。
- The mechanism of elevated intraocular pressure is increased aqueous outflow resistance owing to an accumulation of extracellular matrix material in the trabecular meshwork. 眼压升高的机制被认为是由于小梁网细胞外基质的沉积引起的房水流出阻力增加。
- Changes in the microstructure of the trabecular meshwork may cause a decrease in outflow facility and an increase in IOP. 小梁网显微结构的改变能够引起房水流畅系数的降低而升高眼压。
- The apoptosis of retinal ganglion cells and trabecular meshwork cells plays an important role in the pathogenesis,diagnosis and management of glaucoma. 青光眼视网膜神经节细胞及小梁细胞的凋亡在青光眼的发病机制、诊断治疗中发挥重要作用。
- Trabecular meshwork (TM) transplantation is a replacement of the diseased TM by the functioning TM to lower intraocular pressure. 小梁移植是移植有功能的小梁取代病损小梁,以达到降眼压的目的。
- Purpose: To establish the culture system of human trabecular cells on filter and detect their TEER (trans epithelial electrical resistance ). 目的:建立人眼小梁细胞体外滤膜培养体系及通透阻力测定的模型。
- The role that protein expression regulation of trabecular meshwork cells and the related signal transduction pathways play in the pathogenesis of glaucoma. 小梁细胞蛋白表达调控和相关信号传导通路在青光眼发病过程中的作用。
- Levels of tissue plasminogen activator, stromelysin [34], and metalloproteases [38,39] have been shown to decrease in trabecular meshwork cultures treated with dexamethasone. 在地塞米松处理过的小梁细胞中组织纤维蛋白溶酶原激活剂、基质降解酶[34]和金属蛋白酶[38,39]水平下降。
