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- In treating of leukemia and controlling of minimal-residual disease(MRD),graft versus leukemia effect(GVL) plays a critical role,and complicated mechanisms are involved in this immunology process. 摘要:移植物抗白血病效应(GVL)是异基因造血干细胞移植治疗白血病、控制残留病变的主要机制,蕴涵复杂的免疫学机制。
- Objective To explore the graft versus leukemia effects of donor lymphocyte infusion(DLI) after nonmyeloablative allogeneic bone marrow transplantation while attenuating treatment associated morbidity, mortality and graft versus host disease. 目的 探讨非清除性异基因骨髓移植 (allo BMT)后供者淋巴细胞输注 (DLI)是否能减少移植相关并发症、相关死亡和减轻移植物抗宿主病 (GVHD) ,是否能增强移植物抗白血病 (GVL)效应。
- Preliminary study on graft versus leukemia effect of camouflage of mice bone marrow transplantation with methoxy polyethylene glycol modification 甲氧基聚乙二醇修饰对移植物抗白血病的作用
- haematopoietic stem cell transplantation;acute leukemia;donor lymphocyte infusion;graft versus host disease(GVHD);graft versus leukemia effect;non-myeloablative 造血干细胞移植;非清髓性;供者淋巴细胞输注;急性白血病;移植物抗白血病效应;移植物抗宿主病
- graft versus leukemia effect 移植物抗白血病作用
- Abstract Objective: To explore strategies for preventing graft versus host disease (GVHD) while preserving graft versus leukemia (GVL) effects in allogeneic bone marrow transplantation(BMT). 摘要目的:探讨在异基因骨髓移植治疗白血病中既控制移植物抗宿主病(GVHD)又同时保留移植物抗白血病(GVL)作用的移植方案。
- Objective:To explore strategies for preventing graft versus host disease (GVHD) while preserving graft versus leukemia (GVL) effects in allogeneic bone marrow transplantation(BMT). 目的:探讨在异基因骨髓移植治疗白血病中既控制移植物抗宿主病(GVHD)又同时保留移植物抗白血病(GVL)作用的移植方案。
- To strengthen study on graft versus leukemia 加强对移植物抗白血病作用的研究
- graft versus leukemia 移植物抗白血病
- One known risk is graft versus host disease (GVHD). 一个已知的风险是移植物抗宿主病(GVHD)。
- The result of this attack is called graft versus host disease (GVHD). 输血带来的供者淋巴细胞也可能在受者体内引起类似的反应。
- A pair of contradiction of graft versus host disease (GVHD) and graft versus tumor (GVT) that cannot be attempered. 移植物抗宿主病与移植物抗肿瘤是当前异基因造血干细胞移植中一对不可调和的矛盾。
- The graft versus host disease here is marked by yellow-brown collections of bile in the canaliculi, as well as chronic inflammatory cells within the liver parenchyma. 移植物抗宿主疾病反映的是胆小管内黄棕色的胆汁淤积,同时肝实质慢性炎细胞浸润。
- A severe complication of allogenic haemopoietic stem cell transplantation is graft versus host disease (GVHD) . 异体造血干细胞移植的重要并发症是移植物抗宿主病(GVHD),免疫抑制剂是有效防治GVHD的一类药物。
- A potential risk of donor lymphocyte infusion is severe graft versus host disease (GVHD). 供体淋巴细胞输注的一个潜在风险是严重的移植物抗宿主病(GVHD)。
- Objective To study transfusion associated graft versus host disease(TA-GVHD) in ICU. 目的分析ICU患者中输血相关性移植物抗宿主病(TA_GVHD)的发病情况并对影响因素进行探讨。
- Microscopically, graft versus host disease is one of the best examples of a process called "apoptosis" or single cell necrosis. 镜下,移植物抗宿主反应是说明“程序性细胞死亡”或单个细胞坏死(即调亡)过程的最好例子。
- There are two knotty problems in spleen transplantation, graft versus host reaction (GVHR) and graft hypersplenism, which are ve ry dangerous and uncontrolled. 移植物抗宿主反应(GVHR)和移植脾亢是脾移植的两个棘手问题。
- Graft versus host disease also leads to marked cholestasis in the liver, seen here as large collections of yellow-green bile pigment in the bile canaliculi. 移植物抗宿主病导致明显的肝内胆汁郁积。可见大量的黄色胆汁淤积在胆小管内。
- It was suggested that chimerism and the maintainance of chimerism balance would be of benefit to the prevention and treatment of rejection and graft versus host disease. 认为促进嵌合的出现及保持嵌合的平衡,将有利于防治排斥反应和移植物抗宿主病。