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- The glucagon receptor, a seven-transmembrane domain G-protein-coupled receptor, is an obvious target for the development of small-molecule antagonists. 胰高血糖素的受体是一个有着七次跨膜区域的G蛋白耦联受体,是一个小分子拮抗剂发展的明显的靶点。
- Accordingly, this review ends with a discussion of the status and therapeutic potential of glucagon receptor antagonists, -cell selective somatostatin agonists, glucagon-like peptide-1 agonists, and dipeptidyl peptidase-IV inhibitors. 因此,文章结尾讨论了胰高糖素受体拮抗剂、细胞选择性生长抑素激动剂、胰高糖素样肽-1激动剂和二肽酶-IV抑制剂的情况及其治疗潜能。
- Keywords Glucagon receptor gene Type 2 diabetes mellitus Polymorphism; 胰高血糖素受体基因;2型糖尿病;多态性;
- Keywords glucagon receptor;reporter gene;antagonist;high throughput screening; 关键词胰高血糖素受体;报告基因;拮抗剂;高通量药物筛选;
- The receptor blocker of glucagon is conceivab... 该文就高血糖素及其受体的研究进展作一论述。
- glucagon receptor 胰高血糖素受体
- A sensory receptor that detects warmth. 热探测器测量热量的敏感接受器
- Several non-peptide glucagons receptor antagonists have been reported so far; 一些非肽类的胰高血糖素受体拮抗剂现已报道;
- The liver not only is the receptor of dietary fat. 肝脏是日粮脂肪的接受者。
- A sensory receptor detects warmth. 热探测器是测量热量的敏感接受器。
- Glucagon treatment of liver leads to increased autophagy. 用高血糖素处理肝脏,会导制自噬作用增加。
- Hormone receptor favouring to loss of weight. 偏向体重减轻的荷尔蒙受器。
- Like PFK,it is also regulated hormonally by glucagon. 像 PFK 一样,它也受到胰高血糖素的调节。
- Hormone receptor favouring to obesity. 偏向产生肥胖的荷尔蒙受器。
- Placebo effect tied to brain receptor activity. 安慰剂的效果与大脑内受体活动度有关。
- Receptor and ligand are transported elsewhere. 受体和配基在别处被传递。
- They are found in key receptor areas of the brain. 人们发现它们位于大脑关键的接收区域。
- Vitamin D receptor(VDR) is a steroid hormone. 维生素D受体(vitamin Dreceptor,VDR)属于类固醇类激素。
- Estrogens act through estrogen receptor(ER). 雌激素的作用由雌激素受体(Estrogen Receptor,ER)所介导。
- Burned serum may up-regulate ETB receptor. 烧伤血清可上调亚型B内皮素受体。
