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- Objective To construct the gene vaccine of Coxsackievirus group B type 3(CVB3). 目的探讨构建柯萨奇病毒B组3型（CVB3）基因疫苗的可行性。
- Objective To explore effect of maternal HBV infection on neonatal immunization with hepatitis B gene vaccine. 目的探讨乙型肝炎病毒(BV)染的母亲对新生儿乙型肝炎(称乙肝)因疫苗免疫接种效果的影响。
- Objective To construct a bivalent VP1 gene vaccine against Coxsackie virus B1 and B3 (CVB1 and CVB3) and to test its immunogenicity in mice. 目的 构建柯萨奇病毒 (CV)B1/B3型二价VP1基因免疫质粒 ,并探讨其免疫原性。
- ObjectiveTo study the immunological enhancing effect of human interleukin 15(hIL 15) as gene adjuvant on Coxsackievirus B3(CVB3) VP1 gene vaccine. 目的探讨人白细胞介素 15 (humaninterleukin 15 ,hIL 15 )基因佐剂对柯萨奇B3病毒 (CoxsackievirusB3 ,CVB3 )VP1基因疫苗的免疫增强效果。
- Methods 40 C57BL/6N mice were divided into 5 groups: Mtb8.4/hIL-12 chimeric gene vaccine, Mtb8.4 gene vaccine, BCG, empty vector alone and PBS. 方法将雌性C57BL/6N小鼠40只;随机分为5组;即Mtb8.;4/hIL-12嵌合基因、Mtb8
- The study was aimed at discussing the effect and significance of immunization of NDV F gene vaccine with chicken IL-18 gene. 本研究的目的是探讨NDV F基因DNA疫苗与鸡IL-18基因联合免疫鸡体的效果及意义。
- Co-immunization of Mtb8.4 gene vaccine and plasmid encoding hIL-12 can enhance the specific cellular immune response induced by the Mtb8.4 gene vaccine alone. hIL-12表达质粒能够增强Mtb8.;4基因疫苗所诱导的细胞免疫应答。
- Immuization with Mtb8.4/hIL-12 chimeric gene vaccine could remarkably reduced CFU counts in organs. Conclusion When it was used to construct the chimeric gene vaccine, hIL-12 could improve the immune efficacy of Mtb8.4 gene vaccine. 结论hIL-12与Mtb8.;4构建成嵌合基因疫苗后;使Mtb8
- The two eukaryotic expression vectors containing GAD65 fragment and IL-10 gene can be successfully constructed, which is a foundation for further development of gene vaccine against type 1 diabetes. 成功构建了2种GAD65片段与IL-10双基因真核表达载体,为1型糖尿病的基因疫苗预防研究提供了实验基础。
- In this study, a strain of Recombinant baculovirus can express glycoprotein of RV in mammalian cell was constructed and researched it as antigeng of gene vaccine which can be taken orally. 本实验构建了一株可以在哺乳动物细胞内表达RV糖蛋白的杆状病毒，并对其作为新一代口服基因疫苗的抗原制备进行了探索。
- gosling plague virus VP3 gene vaccine 小鹅瘟病毒vp3基因疫苗
- Objective To investigate the effects of CpG oligodeoxyribonucleotide (ODN) as adjuvants on cellular immune responses in mice immunized with hepatitis B virus (HBV) gene vaccines. 目的 探讨人工合成的含CpG基序的寡核苷酸 (ODN)作为佐剂对乙型肝炎病毒(HBV)基因疫苗诱导小鼠产生细胞免疫应答的影响。
- Screening,cloning,expression,transfer and recombination of immune genes and gene vaccines were expatiated as well. 论述了与免疫功能有关的基因研究,包括免疫基因的筛选、克隆和表达、基因的转移、重组和基因疫苗;
- Basic research and clinical application of gene vaccine 基因疫苗的基础研究及应用现状
- A bivalent VP1 gene vaccine against Coxsackie virus B1/B3 柯萨奇病毒B1/B3型二价VP1基因疫苗的构建及其免疫试验
- Keywords Coxsackievirus;Gene vaccine;Experimental myocarditis; 柯萨奇病毒;基因疫苗;实验性心肌炎;
- The construction of recombinant CEA gene vaccine and its immune effect 癌胚抗原基因重组疫苗的构建及免疫效果观察
- Progress in the Studies of Chickens Infectious Bursal Disease Gene Vaccine 鸡传染性法氏囊病基因疫苗的研制进展
- Development of a Gene Vaccine Containing CpG against Canine Parvovirus Disease 以CpG为佐剂的犬细小病毒基因疫苗的初步研究
- Experimental hepatitis induced by P-glycoprotein gene vaccine in mice P-糖蛋白基因疫苗诱导小鼠实验性肝炎
