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- PURPOSE: To investigate the expression of focal adhesion kinase(FAK) and PTEN in salivary adenoid cystic carcinoma(SACC)and its significance. 摘要目的：探讨黏着斑激酶(FAK)和PTEN基因蛋白在腺样囊性癌组织中的表达及意义。
- FAK (focal adhesion kinase) is a non-receptor tyrosine kinase that is widely expressed in vivo and highly conserved in structure. 粘着斑激酶是一种在体内广泛表达且结构高度稳定的非受体型酪氨酸激酶。
- Focal adhesion kinase (FAK) is the intermediator linking integrins to downstream signal proteins, and plays a key role in multiple signal pathways. 粘着斑激酶（focal adhesion kinase，FAK）则是整合素信号途径中连接整合素与下级信号分子的媒介，是胞内多条信号途径的交汇点。
- To study the effect of antisense focal adhesion kinase (FAK) oligodeoxynucleotide on the biological behaviors of U251 MG cells. 目的探讨反义黏着斑激酶(FAK)对U251人胶质瘤细胞株生物学行为影响。
- The majority of integrin signaling proceeds through focal adhesion kinase (FAK), an essential component of the focal adhesion complex. 大部分整合素的信号传导是通过一种灶性附着复合体的必需物质--灶性粘附激酶实现的。
- Objective The study investigated the effect of gastrin on tyrosine phosphorylation and protein expression of focal adhesion kinase (FAK) in human colon cancer cells. 目的研究胃泌素对人结肠癌细胞信号分子黏着斑激酶(FAK)酪氨酸磷酸化和蛋白质表达的影响。
- The expression and activity of the focal adhesion kinase on cultured Raji cells were regulated by Triptolide,and this regulation may be important in the tumor-pathogesis. 雷公藤内酯醇具有抗淋巴瘤细胞增殖效应,并同时降低FAK含量和活力,提示雷公藤内酯醇抗肿瘤效应可能与抑制黏着斑激酶介导细胞信号转导有关。
- Western blot analysis suggested the decreased cell motility might be attributed to the reduced phosphorylation of focal adhesion kinase (FAK) by PTEN gene delivery. 利用西方墨点法分析可以推测经PTEN基因传送的肝癌细胞移行数目的减少，可能是因降低了FAK磷酸化的缘故所致。
- FAK(focal adhesion kinase) discovered by Schaller is a major substance which can be activated by src-ingeneration protein-tyrosine kinase and it is a non-receptorprotein-tyrosion kinase. 黏着斑激酶(focal adhesion kinase，FAK)是Schaller等发现的能被scr内源性蛋白酪氨酸激酶激活的主要底物，属于非受体蛋白酪氨酸激酶，具有调节细胞发育、生长、存活和凋亡，调节细胞与ECM(细胞外基质)黏附的功能。
- Focal adhesion kinase (FAK) is a critical mediator that connects integrin and the downstream signal molecules in integrin-signal transduction pathway, and is the convergence of many signal pathways. 黏着斑激酶(focal adhesion kinase，FAK)是整合素信号转导通路中连接整合素与下游信号分子的媒介，处于细胞内多条信号转导通路的交汇点，能激活多条信号转导通路。
- focal adhesion kinase gene (FAK) 局部黏着斑激酶基因（FAK）
- Focal adhesion kinase related non -kinase 黏着斑激酶相关非激酶
- Expression of focal adhesion kinase in laryngeal carcinoma 黏着斑激酶在喉癌中的表达及临床意义
- Keywords focal adhesion kinase;tyrosine phosphorylation;cells size; 黏着斑激酶;酪氨酸磷酸化;细胞大小;
- Role of focal adhesion kinase in vascular endothelial cell migration 粘着斑激酶在血管内皮细胞迁移中的作用
- Expression and clinical significance of focal adhesion kinase in colon cancer 黏着斑激酶在结肠癌中的表达与临床意义
- Expression of Focal Adhesion Kinase in Carcinomas and its Clinic Signification 粘着斑激酶在肿瘤中的表达及其临床意义
- Influence of Biomateriai on Focal Adhesion Kinase of Platelet:Ex Vivo Study 生物材料对血小板黏着斑激酶影响的半体内研究
- Keywords focal adhesion kinase;tongue cancer cell;RNA interference;anoikis; 黏着斑激酶;舌癌细胞;RNA干扰;失巢凋亡;
- Effects of X-ray irradiation on focal adhesion kinase in vascular smooth muscle cells X射线对血管平滑肌细胞粘着斑激酶的影响
