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- BackgroundRenal interstitial fibrosis (RIF) is the final common pathway of chronic kidney disease (CKD) to the end stage renal failure (ESRF), characterized with the tubular epithelial cell depletion and expanding of extracelluar matrix (ECM). 肾间质纤维化(RIF)以肾小管上皮细胞丢失和肾脏间质中细胞外基质(ECM)过度沉积为特征，是各种慢性肾脏疾病(CKD)进展到终末期肾衰竭(ESRF)的最终共同途径。 RIF病变程度比肾小球病变更能反映肾功能损害情况。
- final common pathway 最后总路
- Signaling through cAMP-dependent protein kinase (PKA) is a common pathway for many cellular processes. cAMP依赖型蛋白激酶(PKA)在许多激素和神经递质的信号传递过程中起着十分重要的作用。
- OBJECTIVE: The renal interstitial fibrosis(RIF) is almost the common pathway by which all the various chronic kidney diseases (CKD) progress to end stage renal disease(ESRD). 目的：肾间质纤维化(RIF)是各种不同病因的慢性肾脏病(CKD)随着病程进展进入终末期肾病(ESRD)的一个进行性、不可逆的共同途径。
- OBJECTIVE : The tubulointerstitial fibrosis(TIF) and progressive deterioration of the renal impairment are almost the common pathway by which all the kidney diseases progress to end stage renal failure. 目的:肾间质纤维化导致肾脏损害进行性发展,几乎是所有肾脏疾病进展至终末期肾功能衰竭的共同途径。
- Knowledge without common sense counts for little. 光有学问而无常识，则这种学问无甚价值。
- These common pathways may underlie shared rewarding and response mechanisms and may be targets for effective treatments for a wide range of addictive disorders. 这些共同的途径可能是共享性奖励及反应机制的基础,并可能成为有效治疗许多种不同的成瘾性疾病的标靶。
- He was consuming his final libation. 他正在喝着他的最后一杯酒。
- A few jokes will add a final fillip to your speech. 几句笑话会给你的演说添些生气。
- The play is notable for the pathos of its final scene. 该剧以最后一场的哀婉动人而著称。
- Salt is a common food preservative. 盐是一种常用的食物防腐剂。
- The script is massaged into final form. 这篇稿子经过修改已定稿。
- Please dim out the stage for the final scene. 请在最后一场即将开演时使舞台灯光转暗。
- There is still no cure for the common cold. 目前仍没有治愈感冒的良药。
- The final decision rests with him. 最后决定取决于他。
- Huxley, I feel, has much in common with Wells. 我觉得赫胥黎和威尔士有很多共同之处。
- Rabbits and foxes are common in Britain. 兔子和狐狸在英国很常见。
- It always pays to give your paper one final check. 写了东西最后检查一遍总是有好处的。
- Arsenal scored in the final minute of the game. 阿森纳队在比赛的最后一分钟进了一球。
- The game is now in its final stages. 这场比赛现在处于最后阶段。
