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- Objective To prepare a harmine hydrochloride liposome formulation with high encapsulation efficiency. 目的制备高包封率的盐酸去氢骆驼蓬碱脂质体。
- OBJECTIVE To establish the protamine aggregation method for the drug encapsulation efficiency determinations of liposomes and nanoliposomes. 目的建立鱼精蛋白凝聚法测定脂质体、纳米脂质体包封率的方法。
- Protein-loaded microspheres showed good sphericity and narrow diameter distribution, the encapsulation efficiency reached 95%. 微球球形度优良，粒径分布窄，蛋白质包封率达到95%25。
- Results Protein-loaded microspheres showed good sphericity and narrow diameter distribution, the encapsulation efficiency reached 95%. 结果微球球形度优良,粒径分布窄,蛋白质包封率达到95%25。
- Conclusion: We have successfully prepared slow-release nanoparticles harboring BDNF,which are stable and have high encapsulation efficiency. 结论：成功制备的BDNF缓释注射纳米粒具有稳定性好、包封率高的特点。
- Conclusion：Ropivacaine hydrochloride multivesicular liposomes showed high encapsulation efficiency and significant sustained-release feature. 结论：盐酸罗哌卡因多囊脂质体具有较好的缓释效果。
- Conclusion The structures of PLLA-PEG-PLLA triblock copolymer and the types of emulsifiers may relate to surface morphology,encapsulation efficiency a... 结论改变材料的嵌段组成、使用不同的乳化剂均会改变微球的形貌、包封率、粒径等重要性质。
- The encapsulation efficiency and drug loading of triptolide-loaded poly (D,L-lactic acid) nanoparticles were analyzed by RP-HPLC and ultracentrifuge method in this study. 本文研究了反相高效液相色谱和超速冷冻离心测定雷公藤甲素聚乳酸纳米粒包封率和载药量的方法。
- The orthogonal test design by adopting the standard of drug encapsulation efficiency and drug loading was applied to obtain the optimal formulation of the microcapsula. 以药物的包封率和载药量作为制备工艺优化指标,通过正交试验得出微囊的最优处方。
- OBJECTIVE To prepare the stable lipiodol double emulsion with uniform size and high encapsulation efficiency as drug carrier by a novel membrane emulsification technique. 目的采用新型微孔膜乳化法制备粒径均匀、包埋率高、包埋稳定的抗癌剂碘油复乳药物载体。
- The model of the packetization is analyzed and an algorithm of adaptive packetization based on both encapsulation efficiency and video quality is proposed. 为了对比特错误进行控制和恢复,国内外在早期对这方面做了大量研究[1]。
- The encapsulation efficiency of the 5-FU nanoparticle was deter-mined with the result of 29.5%within 72 hours up to 79%drug release was observed from hep-arin-albumin nanoparticles. 以5－氟尿嘧啶为模型药物，将5－氟尿嘧啶肝素钠－白蛋白毫微粒在酸性条件下100℃水解20h，测得5－氟尿嘧啶的平均包封率为29.;5%25。 体外试验结果表明，5－氟尿嘧啶毫微粒在37℃的稀盐酸液中72h累计释药达79
- Because of osmotic pressure, CEZ was lost into the outer water phase resulted from influx of water from the outer phas, the microspheres was more pores and encapsulation efficiency was low. 因此制备得到的微球表面多孔，且包封率较低；
- Additives,especially the additives with polyhydroxy structures,enhancd the encapsulation efficiency in the microspheres,improved the release profiles and stabilized the active proteins,respectively. 附加剂增加微球包封率，改善药物释放，稳定蛋白质活性，尤其是具有多羟基结构的附加剂。
- Methods:The effects of different formulation and technics factors on the particle size,drug loading,and drug encapsulation efficiency were evaluated by single factor design and orthogonal design. 方法:采用单因素法和正交设计法考察不同影响因素对乳化溶剂挥发法所制得的纳米粒粒径、包封率和载药量的影响。
- Objective: To study the effect of surfactants on the flexibility, encapsulation efficiencies and physicochemical properties of ultraflexible nano-liposome of salmon calcitonin. 目的:研究表面活性剂对鲑鱼降钙素柔性纳米脂质体的变形性、包封率及理化性质的影响。
- Encapsulation efficiency was used as the main evaluating index, the optimum composition of encapsulated wall for microencapsulation of jade perch (Scortum barcoo) oil was studied. 以宝石鱼油微胶囊制品包埋率作为主要评价指标,筛选出喷雾干燥法制取宝石鱼油微胶囊壁材配方组成;
- Encapsulating efficiency of 5- FU was det ermined by ultraviolet spectrophotometry. 透析法制备5-FU纳米胶束;
- Encapsulation efficiency was used as the main evaluating index for achieving the best encapsulated wall composition of microencapsulation of jade perch(Scortum barcoo) oil. 以宝石鱼油微胶囊制品的包埋率作为主要评价指标,考察了宝石鱼油微胶囊的壁材配方组成。
- Howeer, the use of nanoparticles for small molecular weight, water-soluble drugs has been limited by poor drug encapsulation efficiency and rapid release of the encapsulated drug. 然而，使用纳米粒包裹小分子量的水溶性药物，会受药物包囊效率低及包囊药物快速释放差的限制。
