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- OBJECTIVE To develop HPLC methods for the enantiomers separation of six pharmaceutical racemates including naftopidil,tamsulosin,carvedilol,racecadotril,sibutramine and rosiglitazone. 目的建立奈哌地尔、消旋卡多曲、坦洛新、西布曲明、罗格列酮和卡维地洛6种药物对映体手性分离方法。
- Applications. Some enantiomers separated by CMPs of CLEC are presented as examples. 应用:列举了一些手性流动相法分离对映体的例子。
- Enantiomeric separation by nonaqueous capillary electrophoresis (NACE) is briefly reviewed with 36 references. 对非水溶液毛细管电泳中手性分离的研究现状和发展趋势进行了简要的评述。
- The direct enantiomer separation of phenlpropanol on three Pirlk types of chiral column Whelk- O 1 , DNB-Leu, DNB-Pg had been studied. 对于手性对映体苯丙醇在3种Pirkle型手性固定相(CSP)Whelk-O1、DNB-Leu和DNB-Pg上直接分离进行了研究。
- The enantiomeric separation of four acidic drugs and one neutral drug on human serum albumin(HSA) chiral stationary phase was described. 考察了4种酸性药物和1种中性药物对映体在人血清白蛋白手性固定相上的保留行为。
- The enantiomeric separation of chiral antifungal drugs miconazole and imazalil on chiral column CTMB (cellulose tris (4-methyl benzoate)) in normal phase mode was described. 摘要在正相体系下,在自制的纤维素三(4-甲基苯甲酸酯)(CTMB)手性固定相上进行咪康唑和抑霉唑对映异构体分离。
- In this article, the separation mode and application of this technique in enantiomer separation were reviewed ,and the choices of experimental condition were discussed. 本文综述了毛细管电色谱在手性分离方面的分离方式及其应用,并对影响手性分离的主要因素作了介绍。
- The results suggest that the structure and concentration of alcohol in the mobile phase have a pronounced effect on enantiomeric separation and retention. 结果发现,在相同的色谱条件下,被拆分簇合物在异丙醇作改性剂的流动相中的拆分效果较好。
- Chiral calixarenes are a class of important host compounds and have wide applications in chiral recognition, enantiomer separation and asymmetrical catalysis. 摘要手性杯芳烃是一类重要的主体化合物,在手性识别、对映体分离和不对称催化等方面有着广泛的用途。
- Chiral ligand-exchange chromatography (CLEC) is one of the basic chromatography method for enantiomer separation, in which chiral ligands and metal ions are two essential elements to determine the chiral selectivity. 手性配体交换色谱法是分离手性化合物的基本方法之一,其中手性配体和金属离子是决定手性化合物分离选择性的根本因素。
- Affinity capillary electrophoresis has been used for the enantiomeric separation of racemic trimebutine maleate with bare fused capillary using human serum albumin(HSA) as chiral selector. 以人血清白蛋白(HSA)为手性选择剂,采用亲和毛细管电泳法分离马来酸曲美布汀对映体。
- Keywords DL amino acid;enantiomers separation;chiral stationary phases (CSPs);recognition mechanism; 乙酰化DL-氨基酸酯;手性分离;对映体;手性固定相;
- A capillary electrophoretic method for the enantiomeric separations of doxazosin and its intermediate was developed. 在此条件下多沙唑嗪及其中间体的对映体均达到了基线分离。
- Separation from her children was a terrible wrench. 同她的孩子们分别是一项很大的痛苦。
- Study on Enantiomers Separation of Tamsulosin Hydrochloride Using Proteinate and Derivatized Cellulose Chiral Stationary Phase 蛋白质及纤维素衍生物手性固定相分离盐酸坦洛新对映体
- DISCUSSION OF THE APPLICATION OF THREE-POINT INTERACTION PRINCIPLE TO THE PHENYLGLYCINE RACEMIC COMPOUND IN IR SPECTROMETRY AND ITS ENANTIOMERS SEPARATION IN HPLC 苯甘氨酸外消旋体的红外光谱及其对映异构体色谱拆分三点作用原理关系间的探讨
- Friends managed to reconcile him with his wife after years of separation. 经过多年分居后朋友们设法使他与妻子重修旧好。
- He was unhappy because of his separation from his mother. 他因与母亲分离而感到不快。
- (C) Applications. Some enantiomers separated by CMPs of CLEC are presented as examples. (C)应用:列举了一些手性流动相法分离对映体的例子。
- (C) Applications.Some enantiomers separated by CMPs of CLEC are presented as examples. (C)应用:列举了一些手性流动相法分离对映体的例子。