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- With further reseaches and applications of thermosensitive gel,the modes and mechanisms of it were discovered and poited out,drug release models were also established step by step. 随着温敏凝胶研究和应用的不断深入,其释药模式及机制被不断提出和发现,不同释药特征的释药模型也相继建立。
- drug release model 释药模型
- The alidated mathematical model can be used to predict small-molecule drug release from PLG microsphere population. 对于多元分散体(分散参数<3)结合微球大小的数学模型比只用平均粒径更与试验结果相符。
- Optimal estimates of the model parameters were obtained by minimizing the difference between model simulation and experimentally measured drug release kinetics. 对模型参数的最佳评价通过最小化模型模拟和实验测定间的药物释放动力学差别来获得。
- Furthermore, our model incorporates mechanisms by which the processes underlying drug release from a polymer matrix can be quantitatively analyzed. 另外,我们的模型整合机制使药物从聚合物基质中释放的过程可以被定量分析。
- SR on the drug release was great, variations of Kollidon? SR用量对药物释放影响较大;
- The mechanism of drug release from swellable polymer was studied . 对药物从亲水聚合物凝胶系统中释放的机理进行了研究。
- The effects of different drug loadings on the drug release rate were simulated and compared with other data to validate this model. 模拟不同载药量对药物释放速率的影响并与其它数据进行比较,以此来验证此模型。
- Furthermore, our model incorporates mechanisms by which the processes underlying drug release from a polymer matrix can be quantitatiely analyzed. 另外,我们的模型整合机制使药物从聚合物基质中释放的过程可以被定量分析。
- The research results showed that the gray GM(1,1) model draw up for drug release had a high accuracy and results was trustiness. 结果表明,用灰色数学模型对药物释放过程进行拟合,拟合精度高,结果可靠。
- This simplified energy release model cannot exactly duplicate the effect of the real distributed energy release process. 这种简化了的能量释放模型不能精确地反映实际分布的能量释放过程的效应。
- Drug release processes of hydrogels in pH2.0 and pH7.4 buffer solution can be described by Ritger-Peppa model and diffuse-relaxation model respectively. 凝胶在pH7.;4缓冲溶液中的释药率高于pH2
- The paddle method was used to study the drug release properties of RFP-PLA-MS. 考察了微球在不同温度下的稳定性;
- The Stress Release Model (SRM) and the Coupled Stress Release Model (CSRM) have been found wide applications in seismicity study. 摘要应力释放模型在地震活动性研究中多有应用。
- Abstract ABSTRACT:Objective To develop a novel drug dilivery system based on calcium phosphate cement (CPC) with methotrexate (MTX) as a model drug and to study its drug release in vitro. 摘要 摘要:目的 观察含甲氨喋呤(MTX)的磷酸钙骨水泥(CPC)的药物释放体系在体外模拟体液中的药物释放情况。
- Objective To prepare Emedastine Difumarate Sustained-release Tablets(EDST),and develop a method for the determination of drug release rate. 目的制备富马酸依美斯汀缓释片,并建立其释放度测定方法。
- The study examine the drug release mechanism of famotidine chitosan microcapsule. 初步研究了法莫替丁-甲壳胺微囊的释药机理。
- Releasing model of menthol and denaturated starch microencapsulation was studied,and its mechanism was discussed in this paper. 研究了薄荷醇-变性淀粉微胶囊释放模型,并初步探讨了其作用机理。
- Accelerated release testing could be applied to evaluate the drug release profile of huperzineA PLGA microspheres. 加速释放度试验可用于快速评价石杉碱甲微球的释药特性。
- Objective To prepare estradiol sustained-release capsules for vagina and evaluate the drug release property. 摘要目的制备雌二醇阴道用缓释胶囊,并考察其体外释药行为。
