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- deoxytetra cycline 脱氧四环素, 强力霉素
- CDK activation by cyclin binding. 1)CDKs结合cyclin后活化。
- Cyclin prognosis of lung cancer patients. 周期蛋白
- Cyclin-cdk compound is composed of Cyclin and cdk different cell cycle. 多种肿瘤存在着Cyclin的异常表达,cdk的激活及其抑制因子的丢失。
- The expression of cyclin D1 and CDK4 were detected by RT PCR method. RT PCR检测细胞周期素D1(cyclinD1)、细胞周期蛋白依赖激酶 4 (CDK4 )mR NA的表达。
- Patients who expressed cyclin D1 were more likely to achieve a response. 表达细胞周期蛋白D1的患者更有可能对治疗有反应。
- Cyclin D3 antisense oligodeoxynucleotides were used in in vitro culture study. 用反义技术和流式细胞术研究周期蛋白D3在白血病细胞增殖中的作用。
- Study on expressions and clinical significance of P~(21) WAF1/CIP_1,CyclinE and PCNA in epithelial ovarian neoplasms. P~(21)WAF1/CIP_1、CyclinE、PCNA在卵巢上皮性肿瘤中的表达与临床意义
- The effect of CyclinE, Cyclin Dl and P21WAF1/CIP1 in CA and their relations to HPV are not clear at present. Cvciln E、Cyclin D1和p21~(WAF1/CIP1)在尖锐湿疣发生发展中的作用及其与HPV的关系如何,目前尚不清楚。
- The cyclin E/cdk_2 kinase activities in HCMV-infected MRC_(-5) cells were relative to the levels of cyclinE essentially. 感染细胞中CyclinE/cdk_2激酶活性基本上与CyclinE含量相关联。
- The Cyclin D3 protein is a member of the D-type cyclins. Cyclin D3蛋白是D型细胞周期蛋白中的一员。
- These data suggest that PAP1 is a putative cyclin and can form cyclin?CDK complex with PHO85 protein. 这表明PAP1能与PHO85形成细胞周期蛋白-CDK复合物,PAP1可能是一种细胞周期蛋白。
- Effects on the protein expression of cyclin A,B_1 and D_1 were assessed by Western Blot. Western印迹检测细胞周期蛋白D1、A和B1表达的变化。
- Cell cycle is mainly regulated by cyclin, cyclin dependent kinase(CDK) and cyclin dependentkinase inhibitor (CDKI). 细胞周期主要是由细胞周期蛋白(cyclin),细胞周期蛋白依赖性激酶(CDKs)和CDK抑制蛋白(CDKI)来调控的。
- Objective To clarify the role of a cell cycle regulator, cyclin D1 and CDK6 in patients with gastric carcinoma. 目的检测细胞周期蛋白D1(cyclin D1)和细胞周期蛋白质依赖激酶6(CDK6)在胃癌组织中的表达情况,分析其表达与胃癌的临床病理因素和预后之间的关系。
- Objective To study the role of cycline dependent kinase 4(CDK4) in the malignant transformation of human fetal lung diploid fibroblast cell(2BS) induced by silica. 目的 探讨细胞周期蛋白依赖激酶K4(CDK4)在石英致人胚肺成纤维细胞(2BS)恶性转化过程中所起的作用,为石英致癌机制提供理论依据。
- Objective: To investigate the expressions of cyclin E,CDK2, and Ki-67 and their clinical significance in leukemia. 的 :探讨白血病细胞周期素E(cyclinE)、细胞周期蛋白依赖性激酶 2 (CDK2 )、细胞增殖相关抗原(Ki 6 7)在白血病中的表达及其临床意义。
- Ribozyme targeting cyclin Dl may effectively inhibit cyclin D1 expression and activation in the HSC T6 cell line. 载体表达的特异性核酶能有效地抑制HSC的细胞周期蛋白D1的表达和激活。
- Conclusions: Overexpression of cyclin D1 and CDK4 may involve in the onco-pathogenesis of ESC. 我们在相应的癌旁组织中亦发现cyclin D1和 CDK4的过表达。
- Cyclin D1 and CDK4 proteins were expressed correctly in insect cells and had their biological activity. 成功构建了细胞周期蛋白D1及CDK4真核杆状病毒表达载体 ;并且在昆虫细胞中正确表达了具有生物活性的细胞周期蛋白D1及CDK4融合蛋白 .