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- Pathological change is chronic and continual advancement,patients can emerge renal inadequacy,uraemia.excitatory autacoid and cytotoxic drug have bad curative effect and major adverse reaction. 病变呈慢性的进行性发展，可逐渐出现肾功能不全、尿毒症。激素、细胞毒类药物疗效欠佳，且有较大的不良反应。
- Adriamycin is frequently used in combination chemotherapy regiments with other cytotoxic drugs. 阿霉素常与其他细胞毒药物合用于化疗方案。
- The mechanism by which chronic-phase CML cells become resistant to conventional cytotoxic drugs, such as hydroxyurea, is unknown. 慢性期CML细胞对常规细胞毒药物，如羟基脲产生抗药性的机理还不清楚。
- Antibody-drug conjugates enhance the antitumor effects of antibodies and reduce adverse systemic effects of potent cytotoxic drugs. 抗体偶联药物能提高抗体的抗肿瘤能力并减少有效细胞毒性药物的系统性副作用。
- The most effective cytotoxic drugs for treatment of metastatic breast cancer are capecitabine, doxorubicin, gemcitabine, the taxanes paclitaxel and docetaxel, and vinorelbine. 治疗转移性乳腺癌的最有效细胞毒类药有卡培他滨、阿霉素、二氟脱氧胞嘧啶、紫杉烷类（紫杉醇和紫杉萜[泰素帝]）、长春瑞滨等。
- Objective To investigate the impacts of cytotoxic drugs on APE/ref-1 expression in A549 cell, in order to find the potential relationship between APE/ref-1 and chemoresistance of NSCLC. 目的 研究细胞毒性药物对A549细胞APE/ref-1表达的影响,初步探讨APE/ref-1与NSCLC耐药性产生的相关性。
- ATP-TCA was used to detect the sensitivity of 35 specimens of fresh cervical cancer to six cytotoxic drugs as follows: paclitaxel (TAX), cisplatin (DDP), bleomycin (BLM), gemcitabine (GEM), 5-fluoruracil (5-Fu), irinotecan (CPT-11). 采用ATP-TCA法对35例宫颈癌患者的新鲜癌组织进行体外药物敏感性测定，分别检测对泰素(TAX)、顺铂(DDP)、博来霉素(BLM)、健择(GEM)、5-氟尿嘧啶(5-Fu)、依立替康(CPT-11)6种化疗药物的敏感性。
- Methods A549 cells were treated with different cytotoxic drugs for 24hours. The changes of APE/ref-1 expression in A549 after drug-treatment were detected by real time PCR, western blot and streptavidin peroxidase immunohistochemistry staining. 方法 通过免疫组化染色明确APE/ref-1在A549细胞中的表达后,以特定浓度的临床常用细胞毒性药物对A549细胞进行诱导,采用实时荧光定量PCR、Western Blot和免疫组化技术检测药物诱导前后A549细胞内APE/ref-1表达的变化情况。
- The nurse diluted the drug with saline water. 护士用生理盐水把药加以稀释。
- We are testing the efficacy of a new drug. 我们正在测试新药的功效。
- Pharmacy cytotoxic drug reconstitution services and role of oncology pharmacists in Hong Kong 香港医院药剂部化疗药物配置服务以及肿瘤学药剂师的作用
- Predictive Value of In Vitro MTT Assay Chemosensitivity Test of Cytotoxic Drug Activity in Cervical Cancer MTT法体外药敏实验预测宫颈癌细胞药物敏感性的初步探讨
- I am surprised to learn that he is taking drug. 听说他在吸毒，我很吃惊。
- His business was a cover for drug dealing. 他的商行是进行毒品交易的幌子。
- Adopting centralized management in compounding cytotoxic drugs 细胞毒药物的集中配制管理
- Use of this drug is now fairly generalized. 这种药现在用得相当普遍。
- He was convicted of drug offences and deported. 他被判犯有毒品罪而遭驱逐出境。
- She pioneered the use of the drug. 是她最先使用的这种药品。
- The new drug has performed well in tests. 那种新药试验效果不错。
- A drug, especially an illicit or addictive one. 麻醉剂尤指非法使用或使人上瘾的麻醉剂
