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- The chemokine receptor CXCR6 and its ligand CXCL16 are involved in inflammation. 趋化因子受体CXCR6 及其配体CXCL16的作用是参与炎症。
- The molecular evolutionary rates of chemokine receptor genes are different, with CXCR4 gene scored the lowest. 趋化因子受体的进化速率不同，其中CXCR4的进化速率最低。
- Abstract： Objective To explore the correlation between structure domains and function of chemokine receptor CXCR4. 摘 要： 目的 认识趋化因子受体CXCR4之结构与功能的关系。
- The aim of this article is to review recent devel-opment of CCR7,a newly identified chemokine receptor,and its ligand CCL21and CCL19. 全文就新近发现的趋化因子受体CCR7及其配体CCL21和CCL19的研究进展作一综述。
- Objective To investigate whether homocysteine (HCY) can induce the expression of chemokine receptor CCR1 mRNA in cultured THP-1 monocytes. 目的 探讨同型半胱氨酸对人单核细胞株THP 1表达趋化因子受体CCR1mRNA的影响。
- Objective To investigate the role of CC chemokine receptor 5(CCR5) in the immunological pathogenesis of hepatitis B(HB). 目的研究细胞趋化因子受体5(CCR5)在乙型病毒性肝炎(HB)免疫发病机制中的作用。
- AIM:To investigate the expression of CC chemokine receptor 7 (CCR7) in different types of lung carcinoma and its clinical significance. 目的:探讨趋化因子受体CCR7在不同类型肺癌组织中的表达及其临床意义。
- Chemokine CCL21 is a ligand of chemokine receptor (CCR)7. It is constitutively expressed at high level in secondary lymphoid organs (thymus, lymph node, spleen). 趋化因子CCL21是趋化因子受体(CCR)7的一个配体。 它在次级淋巴器官(胸腺、淋巴结、脾脏)中组成性高表达。
- Objective To explore the relationship between chemokine receptor CCR5, CCR2 gene polymorphism and Chinese type 1 diabetics, as well as their first relatives. 目的 探讨趋化因子受体CCR2、CCR5基因多态性与 1型糖尿病 (T1DM)及其一级亲属之间的关系 ,并与T2DM及非DM对照进行比较。
- Thymus and activation -regulated chemokine (TARC) , a CC chemokine, was identified as a selective chemoattractant for CC chemokine receptor 4 (CCR4) - expressing cells to ti-uss. 胸腺和活化调节趋化因子(thymus and activation-regulated chemokine，TARC)是CC型趋化因子，其受体是CC趋化因子受体4(CC chemokine receptor 4，CCR4)，在活化的Th2细胞上呈优势表达，它们共同作用使Th2细胞由血液迁移到一定的组织中。
- To investigate the expression of chemokine receptor CCR7 in peripheral lymphocytes of gastric carcinoma and its relationship with clinicopathological characteristics. 目的研究趋化因子受体CCR7在胃癌患者外周血淋巴细胞各亚群的表达，并与健康人进行比较，探讨其与临床病理分期之间的相关性。
- This review focuses on recent advances in understanding the CD4+ CD25+ regulatory T cells, chemokine and receptor, chemokine receptor expressing on CD4+ CD25+ Tr cells and the attraction of these cells by antigen presenting cells (APCs). 了解CD4+CD25+Tr细胞、趋化性细胞因子、趋化性细胞因子受体和表达于CD4+CD25+Tr细胞上的趋化性细胞因子受体以及它们与不同的抗原提呈细胞(APCs)之间的作用的最新研究进展十分必要。
- To explore the role of the autoantibodies(GADA,IAA,ICA), the polymorphisms of chemokine receptor CCR5 , CCR2 , and the expression of CD4+CCR5+ and CD4+CCR3+ in the PBMC of the type 1 diabetes mellitus in prediction and diagnosis type 1 diabetes. 检测1型糖尿病患者的血清自身抗体水平、趋化因子受体CCR5、CCR2的基因多态性，以及趋化因子受体CCR5、ECR3在1型糖尿病患者外周血CD4~+T淋巴细胞中的表达水平，研究这些检测指标对1型糖尿病早期预报和早期诊断的意义。
- The chemokine receptor CCR5 is implicated in the pathogenesis of various inflammatory diseases, such as multiple sclerosis (MS), atherosclerosis, transplant rejection, and autoimmunity. CCR5与多种炎症性疾病的发生密切相关，如多发性硬化症，动脉粥样硬化，移植排斥，自身免疫等。
- Objective To investigate different significance and expression of the CC chemokine receptor CCR7 of T cells from the peripheral blood or skin models in patients with psoriasis vulgaris. 目的探讨趋化因子受体家族中CC趋化因子受体7(CCR7)在寻常型银屑病患者皮损及外周血T细胞上的表达情况。
- In this paper, recent advances in the Study on chemokines and chemokine receptor antagonists were reviewed. 本文对趋化因子及其受体拮抗剂的研究进展进行综述。
- Chemokine receptors are the members of the G-protein coupled receptor(GPCR) supergene family which include seven hepatahelical transmembrane peptides. 趋化因子受体属于G蛋白偶联受体超家族，是含7个穿膜区段的单链受体，胞内区与G蛋白偶联，可产生信号转导。
- The divergence of chemokine or chemokine receptors was earlier than the divergence of vertebrates. 可见基因家族成员的分化早于脊椎动物的分化。
- Chemokine receptors such as CCR5 and CXCR4 are found as coreceptor to enter the host cell by HIV. 摘要趋化因子受体是HIV进入宿主细胞的共受体，特别是CCR5和CXCR4在HIV进入免疫细胞过程中起着重要作用。
- Chemokine receptors such as CCR5 and CXCR4 are fou nd as coreceptor to enter the host cell by HIV. 趋化因子受体是HIV进入宿主细胞的共受体,特别是CCR5和CXCR4在HIV进入免疫细胞过程中起着重要作用。
